Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SSD114 is a novel GABAB receptor positive allosteric modulator.
説明 | SSD114 is a novel GABAB receptor positive allosteric modulator. |
In vivo | Pretreatment with SSD114 hydrochloride significantly influences the onset and duration of loss of righting reflex (LORR) in mice. Statistical analysis reveals that SSD114 hydrochloride effectively reduces the onset of LORR [F(5,30)=4.55, P<0.005], with post hoc analysis demonstrating a notably quicker onset in mice pretreated with doses of 10 mg/kg or higher, compared to those treated with a vehicle. Furthermore, the duration of LORR is extended following pretreatment with SSD114 hydrochloride [F(5,30)=4.81, P<0.005], with post hoc analysis showing a significant increase in LORR duration in mice pretreated with 10 and 100 mg/kg doses when compared to vehicle-treated mice [1]. |
分子量 | 387.83 |
分子式 | C18H21ClF3N3O |
CAS No. | 2319790-02-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (116.03 mM)
You can also refer to dose conversion for different animals. 詳細
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SSD114 HCl 2319790-02-6 Membrane transporter/Ion channel Neuroscience GABA Receptor SSD-114 hydrochloride SSD114 Hydrochloride SSD-114 Hydrochloride SSD 114 Hydrochloride Inhibitor inhibitor inhibit