Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM, respectively)
説明 | Sparsentan (DARA-a) is a first-in-class orally active and highly potent dual endothelin A and angiotensin II receptor antagonist(Ki of 9.3 and 0.8 nM, respectively) |
ターゲット&IC50 | Ang II (human):0.8 nM(ki) , Ang II (rat):0.4 nM(ki), ETA (human):9.3 nM(ki) |
別名 | RE-021, DARA-a |
分子量 | 592.75 |
分子式 | C32H40N4O5S |
CAS No. | 254740-64-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (84.35 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Sparsentan 254740-64-2 Endocrinology/Hormones GPCR/G Protein RAAS Endothelin Receptor RE021 Inhibitor inhibit Angiotensin Receptor RE-021 DARA-a RE 021 inhibitor