Powder: -20°C for 3 years | In solvent: -80°C for 1 year
T-00127_HEV1 is an inhibitor of phosphatidylinositol 4-kinase III beta(PI4KIIIβ, IC50 = 60 nM).
説明 | T-00127_HEV1 is an inhibitor of phosphatidylinositol 4-kinase III beta(PI4KIIIβ, IC50 = 60 nM). |
ターゲット&IC50 | Anti-poliovirus (PV):0.77 μM(EC50), PI4KIIIβ:60 nM |
In vitro | T-00127_HEV1 displays a more potent anti-poliovirus activity (EC50: 0.77 μM) than other candidate compounds (EC50: 1.7 to 4.7 μM). GW5074 and T-00127_HEV1 almost fully inhibit PI4KB kinase activity at 10 μM (3% and 5% of residual activity, respectively), in contrast to AN-12-H5 (108% of activity [no inhibition]) [1]. |
分子量 | 411.5 |
分子式 | C22H29N5O3 |
CAS No. | 900874-91-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 6 mg/ml (14.58 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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T-00127_HEV1 900874-91-1 PI3K/Akt/mTOR signaling PI4K PI4 kinases Inhibitor Phosphatidylinositol 4 kinases T00127_HEV1 inhibit T-00127_HEV-1 T 00127_HEV1 inhibitor