Powder: -20°C for 3 years | In solvent: -80°C for 1 year
T-1101 tosylate (TAI-95 tosylate) is an inhibitor of Hec1/Nek2, with antitumor activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 17,000 | |||
5 mg | 在庫あり | ¥ 41,000 | |||
10 mg | 在庫あり | ¥ 66,500 | |||
25 mg | 在庫あり | ¥ 123,500 | |||
50 mg | 在庫あり | ¥ 178,500 | |||
100 mg | 在庫あり | ¥ 250,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 61,000 |
説明 | T-1101 tosylate (TAI-95 tosylate) is an inhibitor of Hec1/Nek2, with antitumor activity. |
In vitro | T-1101 has good oral absorption, along with potent in?vitro antiproliferative activity (IC50: 14.8-21.5?nM). |
In vivo | T-1101 tosylate can achieve high concentrations in Huh-7 and MDA-MB-231 tumor tissues, and showed promise in antitumor activity in mice bearing human tumor xenografts of liver cancer (Huh-7). |
動物実験 | SCID mice bearing human Huh-7, BT-474, MCF-7, and MDA-MB-231 xenografts. Dosage:25 mg/kg, 50 mg/kg. Oral administration; twice per day; 28 days |
別名 | TAI-95 tosylate |
分子量 | 665.8 |
分子式 | C31H31N5O6S3 |
CAS No. | 2250404-95-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 11 mg/mL (16.52 mM)
You can also refer to dose conversion for different animals. 詳細
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T-1101 tosylate 2250404-95-4 Apoptosis Cytoskeletal Signaling Microtubule Associated TAI95 T1101 Tosylate T1101 tosylate T-1101 Tosylate TAI95 Tosylate TAI-95 T 1101 Tosylate T1101 Inhibitor inhibit T 1101 T-1101 TAI-95 tosylate TAI-95 Tosylate PPI TAI 95 Hec1/Nek2 TAI 95 Tosylate T 1101 tosylate inhibitor