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Search Results for " eNOS "

ターゲット

Methionine Adenosyltransferase (MAT) Adenosine Receptor Adenosine deaminase

448

阻害剤

154

天然化合物

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T82464	eNOS pT495 decoy peptide
	eNOS pT495 decoy peptide specifically inhibits T495 phosphorylation, thereby reducing eNOS uncoupling and mitochondrial redistribution. It is utilized in research on ventilator-induced lung injury [1].
T27624	Iptakalim Hydrochloride		Potassium Channel , AChR
	Iptakalim, a lipophilic para-amino compound, is a novel ATP-sensitive potassium channel (KATP) opener, as well as an α4β2-containing nicotinic acetylcholine receptor (nAChR) antagonist. Iptakalim is also a K(ir) 6.1/SUR2...		Potassium Channel , AChR
T8657	KYP-2047		Others
	KYP-2047 is a very potent, selective Prolyl oligopeptidase (POP) inhibitor.		Others
T21700	NOS-IN-1	2-Imino-4-methylpiperidine (acetate)	NOS
	NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 μM, 0.2 μM, and 1.1μM for human iNOS (hiNOS), hnNOS and heNOS, respectiv...		NOS
T19916	TRIM	1-(2-Trifluoromethylphenyl)imidazole	NOS
	TRIM (1-(2-Trifluoromethylphenyl)imidazole) is an inhibitor of nNOS.		NOS
T9917	Denosumab		RANKL/RANK
	Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand		RANKL/RANK
T65979	Adenosine 5'-monophosphate disodium salt	Adenosine Phosphate Disodium,5‘-AMP-NA2	Nucleoside Antimetabolite/Analog
	Adenosine 5'-monophosphate disodium salt (Adenosine Phosphate Disodium) is a purine nucleotide involved in ATP metabolism and is used to study the effects of ATP on cells and organisms. Adenosine 5'-monophosphate disodiu...		Nucleoside Antimetabolite/Analog
T19464	N6,N6-Dimethyladenosine		Nucleoside Antimetabolite/Analog
	N6,N6-Dimethyladenosine is find in mycobacterium bovis Bacille Calmette-Guérin tRNA.		Nucleoside Antimetabolite/Analog
T9111	8-Azaadenosine		Adenosine deaminase
	8-Azaadenosine, a powerful ADAR1 (ADAR1) and A-to-I editing inhibitor, effectively blocks RNA editing and suppresses proliferation, 3D growth, invasion, and migration in thyroid cancer cells.		Adenosine deaminase
T9727	2'-Fluoro-2'-Deoxyadenosine		Nucleoside Antimetabolite/Analog
	2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors ex...		Nucleoside Antimetabolite/Analog
TNU0429	N6-(2-Hydroxyethyl)adenosine		Calcium Channel
	N6-(2-Hydroxyethyl)adenosine is a Ca2+ antagonist and anti-inflammatory agent that is associated with the control of cerebral and coronary circulation and is thought to possess sedative activity.		Calcium Channel
T41286	N6-Isopentenyladenosine		Endogenous Metabolite , Autophagy
	N6-Isopentenyladenosine, an end product of the mevalonate pathway, is an autophagy inhibitor with anti-melanoma activity. N6-Isopentenyladenosine, an RNA modification found in cytokinins, regulates plant growth/different...		Endogenous Metabolite , Autophagy
T26641L	Apadenoson TFA	BAY 68-4986 TFA,Apadenoson TFA(250386-15-3 Free base),Discontinued TFA	Adenosine Receptor
	Apadenoson TFA is a potent adenosine A2A receptor (A2AR) agonist that can be used to improve survival in patients infected with SARS.		Adenosine Receptor
TNU0178	2'-O-(2-Azidoethyl)adenosine		Nucleoside Antimetabolite/Analog
	2'-O-(2-azidoethyl)adenosine is a purine nucleoside analog with potential antitumor activity. The activity of 2'-O-(2-azidoethyl)adenosine was associated with inhibition of DNA synthesis and apoptosis.		Nucleoside Antimetabolite/Analog
T22466	Adenosine receptor A1 antagonist 5		cAMP
	Adenosine receptor A1 antagonist 5 acts as an adenosine antagonist, is an oxypurine, acts as an insecticide and pest control agent, and has an inhibitory effect on elevated blood pressure.		cAMP
T60103	N6-(p-Hydroxyphenethyl)-Adenosine)		Others
	N6-(p-Hydroxyphenethyl)-Adenosine) is an adenosine analogue.		Others
T34685	Sonedenoson	MRE-0094,MRE0094,MRE 0094
	Sonedenoson( MRE0094) is an adenosine A2A receptor agonist that promotes rapid wound healing.
T6884	Namodenoson	2-Cl-IB-MECA,CF-102	Adenosine Receptor
	Namodenoson (2-Cl-IB-MECA) is an adenosine A3 receptor agonist.		Adenosine Receptor
T17023	Tecadenoson	CVT-510	Adenosine Receptor
	Tecadenoson (CVT-510) is a selective agonist of A1 adenosine receptor.		Adenosine Receptor
T9516	Binodenoson	WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos	Adenosine Receptor
	Binodenoson (WRC 0470) is a potent and selective A2A adenosine receptor agonist (KD=270 nM). Binodenoson is being developed as a short-acting coronary vasodilator as an adjunct to radiotracers for use in myocardial stres...		Adenosine Receptor
T7188	Piclidenoson	CF-101,IB-MECA	Apoptosis , Adenosine Receptor
	Piclidenoson (CF-101), a selective agonist of adenosine A3 receptor(EC50 values of 0.11 μM), induces robust anti-inflammatory effect in psoriasis patients.		Apoptosis , Adenosine Receptor
T14127	Adenosine A1 receptor activator T62		Adenosine Receptor
	Adenosine A1 receptor activator T62 is an allosteric enhancer of adenosine A1 receptor, and it produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of inflammatory and nerve...		Adenosine Receptor
T12160	N6-Cyclohexyladenosine	CHA	Adenosine Receptor
	N6-Cyclohexyladenosine (CHA) is a selective agonist of A1 receptor with EC50 of 8.2 Nm. N6-Cyclohexyladenosine exerts anticonvulsant effects and protects against neuronal death. CHA was also found to inhibit the pressor ...		Adenosine Receptor
T60531	2'-C-Methyladenosine		HCV Protease
	2'-C-Methyladenosine is an inhibitor of hepatitis C virus (HCV) replication and a ribonucleoside diphosphate reductase inhibitor from Corynebacterium renalis.2'-C-Methyladenosine inhibits HCV replicon and NS5B-catalyzed ...		HCV Protease
T21017	5'-Amino-5'-deoxyadenosine	5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo	Apoptosis , Adenosine Receptor
	5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor targeting malignant tumors of the inert lymphatic system with antitumor and anticancer effects.The anticancer mechanism of 5'-Amino-5'-deoxyadenosine ...		Apoptosis , Adenosine Receptor
T22231	Adenosine Dialdehyde (ADOX)	Periodate-oxidized adenosine,Adenosine, periodate oxidized,Adenox,Adenosinedialdehyde	Others
	Adenosine Dialdehyde (Periodate-oxidized adenosine) is a purine nucleoside analogue. Adenosine Dialdehyde is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent...		Others
T19661	8-Chloroadenosine	NSC 354258,8-Cl-Ado,NSC354258,NSC-354258	AMPK
	8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia. 8-chloroadenosine activity is associated with inhibition of the mTOR pathway.8-Ch...		AMPK
T31731	Evodenoson	DE 112,DE-112,ATL 313,DE112,ATL313,ATL-313	Adenosine Receptor
	Evodenoson (ATL313) is a potent and selective adenosine A2a receptor (A2aR) agonist for the treatment of eye diseases, tumors, and immune system disorders, and may be used in studies of open-angle glaucoma and blood tumo...		Adenosine Receptor
TNU0060	3’-O-Methyladenosine		Antiviral , Adenosine deaminase
	3’-O-Methyladenosine is an antiviral compound with inhibitory activity against West Nile Virus and can be used for the treatment of viral infections.3’-O-Methyladenosine inhibits adenosine deaminase type VII with a Ki va...		Antiviral , Adenosine deaminase
T60020	5'-Fluoro-5'-deoxyadenosine	5'-Fluoro-5'-deoxy-adenosine	Others
	5'-Fluoro-5'-deoxyadenosine (5'-Fluoro-5'-deoxy-adenosine) is utilized commonly as a tool for studying the Actinomycete bacterium Streptomyces cattleya.		Others
TNU1119	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite		Nucleoside Antimetabolite/Analog
	N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite is an adenine nucleoside analog with potential vasodilator activity and anticancer activity for cancer research.		Nucleoside Antimetabolite/Analog
T23636	Adenosine N1-oxide	ANO,1-Oxoadenosine,Adenosine N1 oxide,Adenosine, 1-oxide	Immunology/Inflammation related
	Adenosine N1-oxide (1-Oxoadenosine), which is found in royal jelly, inhibited the secretion of inflammatory mediators by activated macrophages and reduced lethality in lipopolysaccharide (LPS)-induced endotoxin shock.		Immunology/Inflammation related
T7683	Adenosine amine congener	ADAC	Adenosine Receptor
	Adenosine amine congener (ADAC) (ADAC) is an agonist of selective A1 adenosine receptor,.		Adenosine Receptor
T7736	2-Chloroadenosine		Adenosine Receptor
	2-Chloroadenosine (CADO) is a metabolically stable analog of adenosine that binds to adenosine A1, A2A, and A3 receptors( Ki:300, 80, and 1,900 nM, respectively)		Adenosine Receptor
T12163	N6-(2-Phenylethyl)adenosine	N6-Phenethyladenosine,N6-Phenylethyladenosine	Adenosine Receptor
			Adenosine Receptor
TNU0007	3'-Deoxy-3'-fluoroadenosine		Nucleoside Antimetabolite/Analog
	3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borne encephalitis virus (TBEV), Zika virus and West Nile virus (WNV...		Nucleoside Antimetabolite/Analog
T10247	Adenosine 5'-diphosphoribose sodium	Adenosine 5'-diphosphoribose sodium,ADP ribose sodium	Endogenous Metabolite , TRP/TRPV Channel , Autophagy
			Endogenous Metabolite , TRP/TRPV Channel , Autophagy
T34914	Trabodenoson	INNO-8875,INO-8875,PJ875,PJ-875,INNO 8875,INNO8875,PJ 875	Adenosine Receptor
	Trabodenoson (INO-8875) is a selective and potent adenosine A1 receptor agonist, an adenosine analog, for the study of primary open-angle glaucoma.		Adenosine Receptor
T5949	Dideoxyadenosine
	2',3'-Dideoxyadenosine is an inhibitor of HIV replication with antiretroviral activity and antiviral efficacy [1].
T32826	LNA-Adenosine	LNA-A,LNA Adenosine,2'-O,4'-C-Methyleneadenosine	Nucleoside Antimetabolite/Analog
	LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.		Nucleoside Antimetabolite/Analog
T10111	3-Deazaadenosine hydrochloride		Others , HIV Protease
	3-Deazaadenosine hydrochloride is an inhibitor of S-adenosylhomocysteine hydrolase (Ki: 3.9 µM). It has anti-inflammatory, anti-proliferative, and anti-HIV activity.		Others , HIV Protease
T9745	Elevenostat		HDAC
	Elevenostat is an HDAC11-selective inhibitor with an IC50 value of 0.235 µM.		HDAC
T28748	Selodenoson	RG14202,DTI0009,DTI-0009,RG-14202,DT-009,DT009	Adenosine Receptor
	Selodenoson (RG-14202) is a selective adenosine A1 receptor agonist used to slow the heart rate in patients with atrial fibrillation and to treat arrhythmias.		Adenosine Receptor
TNU0085	2'-Deoxy-2'-fluoroarabinoadenosine		Nucleoside Antimetabolite/Analog
	2'-Deoxy-2'-fluoroarabinoadenosine is a nucleoside analogue with extensive anti-tumor activity and can be used for the study of tumor diseases.		Nucleoside Antimetabolite/Analog
T19841	Tribenoside	Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,TBGF	Others
	Tribenoside (BG-356) is a vasoprotectant with mild anti-inflammatory, analgesic, and wound healing properties.		Others
TNU0355	N6-Methyl-2'-O-methyladenosine	N6,2′-O-Dimethyladenosine	Nucleoside Antimetabolite/Analog
	N6-Methyl-2'-O-methyladenosine (N6,2′-O-Dimethyladenosine), a substrate for adiposity and obesity-related genes (FTO), is a reversible modifier compound found on a wide variety of RNA molecules.N6,2′-O-Dimethyladenosine ...		Nucleoside Antimetabolite/Analog
T16263	N6-Cyclopentyladenosine	UK-80882,CPA	Adenosine Receptor
	N6-Cyclopentyladenosine (CPA) is a selective agonist of the adenosine A1 receptor and can be used to mimic the action of the adenosine A1 receptor, with Ki's of 2.3 nM, 790 nM, and 43 nM for human A1, A2A, and A3 recepto...		Adenosine Receptor
T10066	2',5'-Dideoxyadenosine		Adenylyl cyclase , Adrenergic Receptor , AChR
	2',5'-Dideoxyadenosine is a potent and non-competitive adenylyl cyclase inhibitor via binding the P-site (IC50: 3 μM).		Adenylyl cyclase , Adrenergic Receptor , AChR
TQ0125	Capadenoson	BAY 68-4986	Adenosine Receptor
	Capadenoson (BAY 68-4986) is a selective adenosine-A1 receptor agonist.		Adenosine Receptor
T7340	5'-N-Ethylcarboxamidoadenosine	NECA	Adenosine Receptor
	5'-N-Ethylcarboxamidoadenosine (NECA) is an agonist of Adenosine receptor, increases cerebral extravasation of fluorescein and low molecular weight dextran independent of blood-brain barrier modulation.		Adenosine Receptor

Compounds

eNOS pT495 decoy peptide

T82464

Synonym:

Target:

Iptakalim Hydrochloride

T27624

Synonym:

Target: Potassium Channel, AChR

Synonym: 2-Imino-4-methylpiperidine (acetate)

Target: NOS

TRIM

T19916

Synonym: 1-(2-Trifluoromethylphenyl)imidazole

Adenosine 5'-monophosphate disodium salt

T65979

Synonym: Adenosine Phosphate Disodium,5‘-AMP-NA2

Target: Nucleoside Antimetabolite/Analog

N6,N6-Dimethyladenosine

T19464

Synonym:

Target: Nucleoside Antimetabolite/Analog

8-Azaadenosine

T9111

Synonym:

Target: Adenosine deaminase

2'-Fluoro-2'-Deoxyadenosine

T9727

Synonym:

Target: Nucleoside Antimetabolite/Analog

N6-(2-Hydroxyethyl)adenosine

TNU0429

Synonym:

Target: Calcium Channel

N6-Isopentenyladenosine

T41286

Synonym:

Target: Endogenous Metabolite, Autophagy

Apadenoson TFA

T26641L

Synonym: BAY 68-4986 TFA,Apadenoson TFA(250386-15-3 Free base),Discontinued TFA

Target: Adenosine Receptor

2'-O-(2-Azidoethyl)adenosine

TNU0178

Synonym:

Target: Nucleoside Antimetabolite/Analog

Adenosine receptor A1 antagonist 5

T22466

Synonym:

Target: cAMP

N6-(p-Hydroxyphenethyl)-Adenosine)

Synonym: MRE-0094,MRE0094,MRE 0094

Target:

Namodenoson

T6884

Synonym: 2-Cl-IB-MECA,CF-102

Target: Adenosine Receptor

Tecadenoson

T17023

Synonym: CVT-510

Target: Adenosine Receptor

Binodenoson

T9516

Synonym: WRC 0470,MRE-0470,2-(cyclohexylmethylidenehydrazino)adenos

Target: Adenosine Receptor

Piclidenoson

T7188

Synonym: CF-101,IB-MECA

Target: Apoptosis, Adenosine Receptor

Adenosine A1 receptor activator T62

T14127

Synonym:

Target: Adenosine Receptor

N6-Cyclohexyladenosine

T12160

Synonym: CHA

Target: Adenosine Receptor

5'-Amino-5'-deoxyadenosine

T21017

Synonym: 5' Amino 5' deoxyadenosine,5'Amino5'deoxyadenosine,Nsc 238990,NH2dAdo

Target: Apoptosis, Adenosine Receptor

Adenosine Dialdehyde (ADOX)

T22231

Synonym: Periodate-oxidized adenosine,Adenosine, periodate oxidized,Adenox,Adenosinedialdehyde

Target: Others

8-Chloroadenosine

T19661

Synonym: NSC 354258,8-Cl-Ado,NSC354258,NSC-354258

Target: AMPK

Evodenoson

T31731

Synonym: DE 112,DE-112,ATL 313,DE112,ATL313,ATL-313

Target: Adenosine Receptor

3’-O-Methyladenosine

TNU0060

Synonym:

Target: Antiviral, Adenosine deaminase

5'-Fluoro-5'-deoxyadenosine

T60020

Synonym: 5'-Fluoro-5'-deoxy-adenosine

Target: Others

N6-Bz-5'-O-DMTr-3'-deoxyadenosine-2'-O-CED-phosphoramidite

TNU1119

Synonym:

Target: Nucleoside Antimetabolite/Analog

Adenosine N1-oxide

T23636

Synonym: ANO,1-Oxoadenosine,Adenosine N1 oxide,Adenosine, 1-oxide

Target: Immunology/Inflammation related

Adenosine amine congener

T7683

Synonym: ADAC

Target: Adenosine Receptor

2-Chloroadenosine

T7736

Synonym:

Target: Adenosine Receptor

N6-(2-Phenylethyl)adenosine

T12163

Synonym: N6-Phenethyladenosine,N6-Phenylethyladenosine

Target: Adenosine Receptor

3'-Deoxy-3'-fluoroadenosine

TNU0007

Synonym:

Target: Nucleoside Antimetabolite/Analog

Adenosine 5'-diphosphoribose sodium

T10247

Synonym: Adenosine 5'-diphosphoribose sodium,ADP ribose sodium

Target: Endogenous Metabolite, TRP/TRPV Channel, Autophagy

Trabodenoson

T34914

Synonym: INNO-8875,INO-8875,PJ875,PJ-875,INNO 8875,INNO8875,PJ 875

Target: Adenosine Receptor

Synonym: LNA-A,LNA Adenosine,2'-O,4'-C-Methyleneadenosine

Target: Nucleoside Antimetabolite/Analog

3-Deazaadenosine hydrochloride

T10111

Synonym:

Target: Others, HIV Protease

Synonym: RG14202,DTI0009,DTI-0009,RG-14202,DT-009,DT009

Target: Adenosine Receptor

2'-Deoxy-2'-fluoroarabinoadenosine

TNU0085

Synonym:

Target: Nucleoside Antimetabolite/Analog

Tribenoside

T19841

Synonym: Glyvenol,Glyvenal,Ba 2140,BG-356,Glivenol,TBGF

Target: Others

N6-Methyl-2'-O-methyladenosine

TNU0355

Synonym: N6,2′-O-Dimethyladenosine

Target: Nucleoside Antimetabolite/Analog

N6-Cyclopentyladenosine

T16263

Synonym: UK-80882,CPA

Target: Adenosine Receptor

2',5'-Dideoxyadenosine

T10066

Synonym:

Target: Adenylyl cyclase, Adrenergic Receptor, AChR

Capadenoson

TQ0125

Synonym: BAY 68-4986

Target: Adenosine Receptor

5'-N-Ethylcarboxamidoadenosine

T7340

Synonym: NECA

Target: Adenosine Receptor

カタログ番号	製品名	別名	ターゲット
T0683	Mevastatin	Compactin,ML236B	Apoptosis , Antibacterial , Antibiotic , HMG-CoA Reductase , Autophagy , Lipid
	Mevastatin (ML236B) is an HMG-CoA reductase inhibitor that was initially isolated from the mold Pythium ultimum. Mevastatin was the first statin to enter clinical trials.
T1079	Metronidazole	Flagyl,Metronidazol,Anagiardil	Apoptosis , NADPH , Hydrogenase , Antibacterial , Antibiotic , Parasite , Antifection
	Metronidazole (Metronidazol) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
T37635	2'-Deoxyadenosine-5'-triphosphate trisodium	dATP trisodium	DNA/RNA Synthesis , Endogenous Metabolite
	2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide that serves as a substrate for DNA polymerase, which is used in cells for DNA synthesis or replication.		DNA/RNA Synthesis , Endogenous Metabolite
TN1721	Gypenoside L		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
	Gypenoside L inhibits autophagic flux and induces cell death in human esophageal cancer cells through endoplasm reticulum stress-mediated Ca2+ release. It also inhibit non-small cell lung carcinoma A549 cell inhibitory a...		ERK , p38 MAPK , Calcium Channel , NF-κB , ROS
TN1686	Ginsenoside Rg4		Antibacterial
	Ginsenoside Rg4 is a natural product		Antibacterial
TN2296	Vinaginsenoside R4		Others
	Vinaginsenoside R4 was isolated from the leaves of hydroponically grown ginseng. It inhibits melanin biosynthesis and enhances pigmentation in zebrafish without any cytotoxic effects on melan-a cells. It may have potenti...		Others
T4S1518	Pseudoginsenoside RT1		Others
	Pseudoginsenoside RT1, isolated from the fruit of Randia siamensis, exhibits acute ichthyotoxic activity. Pseudoginsenoside RT1 can cause a decrease in blood pressure, an increase in heart rate and an increase in spontan...		Others
TN1096	Ginsenoside Ra1		Others , Tyrosine Kinases
	Ginsenoside Ra1 is a component from ginseng. Ginsenoside Ra1 shows significant inhibitory effects on protein tyrosine kinase (PTK) activation induced by hypoxia/reoxygenation (H/R).		Others , Tyrosine Kinases
T2822	Ginsenoside Rb1	Gypenoside Ⅲ,Gypenoside III	ATPase , Mitophagy , IRAK , NF-κB , Autophagy , HSV
	Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.		ATPase , Mitophagy , IRAK , NF-κB , Autophagy , HSV
T2777	Ginsenoside Rg1	Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,Panaxoside A,Ginsenoside A2	Apoptosis , Beta Amyloid , NF-κB
	Ginsenoside Rg1 (Panaxoside Rg1) is a class of steroid glycosides, and triterpene saponins found exclusively in the plant genus Panax (ginseng). It improves spatial learning and increase hippocampal synaptophysin level i...		Apoptosis , Beta Amyloid , NF-κB
T3385	Gypenoside XVII	GP-17,Gynosaponin S	Estrogen Receptor/ERR , GSK-3 , Endogenous Metabolite
	Gypenoside XVII (Gynosaponin S) confers protection against Aβ25-35-induced neurotoxicity through estrogen receptor-dependent activation of PI3K/Akt pathways, activation of Nrf2/ARE/HO-1 and inactivation of GSK-3β pathway...		Estrogen Receptor/ERR , GSK-3 , Endogenous Metabolite
T3S2296	Gardenoside		Others
	Gardenoside has hepatoprotective, pain‑relieving, and anti-mastitis effects. it may be a potential therapeutic herb against NASH by suppressed supernatant inflammatory cytokine production and intracellular NFkB act...		Others
T2959	Ginsenoside Rh2	20(S)-Rh2,20S-Ginsenoside Rh2,20(S)-Ginsenoside Rh2	Apoptosis , EGFR , Caspase , Endogenous Metabolite
	Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.		Apoptosis , EGFR , Caspase , Endogenous Metabolite
T2752	2'-Deoxyadenosine monohydrate		Others , Endogenous Metabolite
	Deoxyadenosine, a deoxyribonucleoside, is a derivative of the nucleoside adenosine, differing from the latter by the replacement of a hydroxyl group (-OH) by hydrogen (-H) at the 2' position of its ribose sugar moiety.		Others , Endogenous Metabolite
T7571	1-Methyladenosine		Endogenous Metabolite
	1-Methyladenosine (M1A) belongs to the class of organic compounds known as purine nucleosides.		Endogenous Metabolite
T3920	Pseudoginsenoside F11	Ginsenoside A1	Others , Endogenous Metabolite
	Pseudoginsenoside F11 (Ginsenoside A1) is a component of Panax quinquefolium (American ginseng) which main pharmacological activities are positive inotropic effect on isolated heart function, good therapeutic effect on m...		Others , Endogenous Metabolite
T3918	Ginsenoside Rb3	Gypenoside IV	NF-κB , COX , NO Synthase
	Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity. It also inhibits the induction of COX-2 and iNOS mRNA.		NF-κB , COX , NO Synthase
T2878	Ginsenoside Rd	Panaxoside Rd,Sanchinoside Rd,Gypenoside VIII	P450 , Calcium Channel , NF-κB , COX , Endogenous Metabolite
	Ginsenoside Rd (Gypenoside VIII) may have properties that inhibit or prevent the growth of tumors.
T3402	20(S)-Ginsenoside Rg3	20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3	EGFR , Beta Amyloid , Potassium Channel , NF-κB , COX , Sodium Channel , Endogenous Metabolite
	20(S)-Ginsenoside Rg3 (Rg3) possess an ability to inhibit the lung metastasis of tumor cells via inhibition of the adhesion and invasion of tumor cells. It inhibits the proliferation of human umbilical vein endothelial c...
T2985	Gypenoside XLIX		PPAR
	Extracted from whole herb of Gynostemsma pentaphyllum(Thunb.)Mak.;Store the product in sealed, cool and dry condition		PPAR
T3830	20(R)-Ginsenoside Rg2	20R-Ginsenoside Rg2	IL Receptor
	20(R)-Ginsenoside Rg2 (20R-Ginsenoside Rg2) is a compound with anti-oxidant and anti-apoptosis.		IL Receptor
T6S1495	Ginsenoside Rk3		Others , NF-κB
	1. Ginsenoside Rk3 and Rh4 could have a role in treating inflammatory diseases. 2. Ginsenoside Rk3 is often used as a major ingredient of the compound preparation for ischemic heart diseases.		Others , NF-κB
TWS0902	Gypenoside A		Others
	anticancer		Others
T20041	2'-Deoxyadenosine	NSC-141848,NSC141848,NSC 141848	Endogenous Metabolite
	2'-Deoxyadenosine (NSC-141848) is the DNA nucleoside A. It pairs with deoxythymidine (T) in double-stranded DNA.		Endogenous Metabolite
T3915	Ginsenoside Ro	Chikusetsusaponin 5,Polysciasaponin P3,Chikusetsusaponin V	Calcium Channel , Reductase , Prostaglandin Receptor
	Ginsenoside Ro (Chikusetsusaponin V) can reduce TXA2 production, weakly reduce COX-1 and TXAS activities, and has antiplatelet effects as a Ca2+ antagonist with an IC50 of 155 μM.		Calcium Channel , Reductase , Prostaglandin Receptor
T12164	N6-(4-Hydroxybenzyl)adenosine	Para-topolin riboside	P2Y Receptor
	N6-(4-Hydroxybenzyl)adenosine (Para-topolin riboside) is a platelet aggregation inhibitor.		P2Y Receptor
TN2802	20-O-Glucoginsenoside Rf		Others
	20-O-Glucoginsenoside Rf is a natural product extracted from Panax ginseng C. A. Mey.		Others
TN1997	Notoginsenoside FP2		Others
	Notoginsenoside FP2 is a natural product isolated from the fruit pedicels of Panax notoginseng and can be used in studies about the treatment of cardiovascular diseases.		Others
T1723	Adenosine 5'-diphosphate	Adenosine diphosphate,adenosine pyrophosphate,ADP	Endogenous Metabolite
	Adenosine 5'-diphosphate (ADP) induces human platelet aggregation and non-competitively blocks the stimulated human platelet adenylate cyclase.		Endogenous Metabolite
TN1507	Clematichinenoside AR		TNF , Autophagy
	Clematichinenoside AR exerts anti-inflammatory and immunosuppressive properties, it has anti-arthritic effects on PI3K/Akt signaling pathway and TNF-α± associated with collagen-induced arthritis.		TNF , Autophagy
T4447	S-(5'-Adenosyl)-L-methionine tosylate	SAMe,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt	Others
	S-(5'-Adenosyl)-L-methionine tosylate (SAMe) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases [1]. S-(5'-Adenosyl)-L-methioni...		Others
T40370	2′-Deoxyadenosine 5′-monophosphate disodium		Endogenous Metabolite
	2′-Deoxyadenosine 5′-monophosphate disodium, a nucleic acid AMP derivative, is a deoxyribonucleotide present in DNA. It is employed for researching adenosine-based interactions within DNA synthesis and damage analysis.		Endogenous Metabolite
TN7208	2-Methyladenosine	2-methyl adenosine	Others
	2-Methyladenosine (2-methyl adenosine) is a marine derived natural products found in Family Tethyidae.		Others
T6S1500	Ginsenoside Rf	Ginsenoside-Rf,Panaxoside Rf	Calcium Channel , Endogenous Metabolite
	Ginsenoside Rf (Panaxoside Rf) is a trace component of ginseng root. Ginsenoside Rf inhibits N-type Ca2+ channel.		Calcium Channel , Endogenous Metabolite
T2207	Adrenosterone	11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G	Androgen Receptor , Endogenous Metabolite
	Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex.		Androgen Receptor , Endogenous Metabolite
T5S1590	Notoginsenoside Fe	Notoginseng triterpenes,Ginsenoside Mb	Others
	Notoginsenoside Fe (Ginsenoside Mb) is a natural compound found in Panax japlcus var.		Others
T2961	Notoginsenoside R1	Sanqi glucoside R1,Sanchinoside R1	Apoptosis , ERK , Beta Amyloid
	Notoginsenoside R1 (Sanchinoside R1) has been shown to exhibit antioxidant, antiapoptotic, anti-inflammatory, and immune-stimulatory properties.		Apoptosis , ERK , Beta Amyloid
TN1008	Psoralenoside		CaMK , Calcium Channel , Histamine Receptor
	Psoralenoside is a natural product isolated from the fruits of Psoralea corylifolia, shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity.		CaMK , Calcium Channel , Histamine Receptor
T5079	Adenosine 5'-diphosphate sodium salt	Adenosine-5'-diphosphate trisodium salt,ADP sodium salt	Others , Endogenous Metabolite
	Adenosine 5'-diphosphate sodium salt (ADP sodium salt) is an adenine nucleotide that is phosphorylated into ATP by ATPase. This phosphorylation is a key part of cellular homeostatis as it allows for energy storage and is...		Others , Endogenous Metabolite
T13482	2'-O-Methyladenosine		Endogenous Metabolite
	2'-O-Methyladenosine, a methylated adenine residue is found in the urine of normals and adenosine deaminase deficient patients. It shows unique hypotensive activities.		Endogenous Metabolite
T3812	(20R)-Ginsenoside Rg3	20(R)-Ginsenoside Rg3,(20R)Ginsenoside Rg3,20(R)-Propanaxadiol	Others
	(20R)-Ginsenoside Rg3 (20(R)-Propanaxadiol) is a compound with anti-aging and antifatigue activities.		Others
T4S1519	Pseudoginsenoside RT5		Others
	1. Pseudoginsenoside RT5 has anti-epilepsy, anti-depressant activity by promoting nerve growth and improve cognitive ability. 2. Pseudoginsenoside RT5 has anti-bacterial, anti-tumor and anti-malaria activities.		Others
TN2208	Siamenoside I		Others , LDL
	Siamenoside I is a natural product,and is one of the mogrosides that has several kinds of bioactivities, it exhibits maltase inhibitory effect with the IC50 value of 12 mM.		Others , LDL
T3829	Ginsenoside F3		Others , IFNAR , Interleukin
	Ginsenoside-F3 has immunoenhancing activity by regulating production and gene expression of type 1, type 2 cytokines in murine spleen cells. Ginsenoside-F3 enhances the NF-kappaB DNA binding activity induced by ConA in m...		Others , IFNAR , Interleukin
T2873	Ginsenoside Rg2	Chikusetsusaponin I,Panaxoside Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2	Beta Amyloid , GSK-3 , NF-κB
	Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor.		Beta Amyloid , GSK-3 , NF-κB
T2872	Ginsenoside Re	Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re	Beta Amyloid , NF-κB , Endogenous Metabolite , JNK
	Ginsenoside Re (Ginsenoside B2) may have properties that inhibit or prevent the growth of tumors.		Beta Amyloid , NF-κB , Endogenous Metabolite , JNK
T2932	Ginsenoside Rh1	Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1	IL Receptor , TNF , Endogenous Metabolite , PPAR , Interleukin
	Ginsenoside Rh1 (Sanchinoside B2) , one of the main constituents of Panax ginseng, exhibits anti-inflammatory effect.
T3811	Ginsenoside C-K	Ginsenoside compound K,Ginsenoside K	P450 , cell cycle arrest , COX , NO Synthase
	Ginsenoside C-K (Ginsenoside K) is a bacterial metabolite of G-Rb1 exhibiting anti-inflammatory effects by reducing iNOS and COX-2.		P450 , cell cycle arrest , COX , NO Synthase
T3813	20(R)-Ginsenoside Rh2	(20R)Ginsenoside Rh2,Ginsenoside Rh2	Apoptosis , MMP , HSV
	20(R)-Ginsenoside Rh2 (Ginsenoside Rh2) is a minor stereoisomer of ginsenoside Rh2, possesses matrix metalloproteinase inhibitory.		Apoptosis , MMP , HSV
T3919	Ginsenoside Rb2	Ginsenoside C	GPR , Others , Influenza Virus , Endogenous Metabolite
	Ginsenoside Rb2 (Ginsenoside C) found in species of Panax, upregulating GPR120 gene expression.		GPR , Others , Influenza Virus , Endogenous Metabolite
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天然物製品

Mevastatin

T0683

Synonym: Compactin,ML236B

Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid

Metronidazole

T1079

Synonym: Flagyl,Metronidazol,Anagiardil

Target: Apoptosis, NADPH, Hydrogenase, Antibacterial, Antibiotic, Parasite, Antifection

2'-Deoxyadenosine-5'-triphosphate trisodium

T37635

Synonym: dATP trisodium

Target: DNA/RNA Synthesis, Endogenous Metabolite

Gypenoside L

TN1721

Synonym:

Target: ERK, p38 MAPK, Calcium Channel, NF-κB, ROS

Ginsenoside Rg4

TN1686

Synonym:

Target: Antibacterial

Pseudoginsenoside RT1

Target: Others, Tyrosine Kinases

Ginsenoside Rb1

T2822

Synonym: Gypenoside Ⅲ,Gypenoside III

Target: ATPase, Mitophagy, IRAK, NF-κB, Autophagy, HSV

Ginsenoside Rg1

T2777

Synonym: Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,Panaxoside A,Ginsenoside A2

Target: Apoptosis, Beta Amyloid, NF-κB

Gypenoside XVII

T3385

Synonym: GP-17,Gynosaponin S

Target: Estrogen Receptor/ERR, GSK-3, Endogenous Metabolite

Synonym: 20(S)-Rh2,20S-Ginsenoside Rh2,20(S)-Ginsenoside Rh2

Target: Apoptosis, EGFR, Caspase, Endogenous Metabolite

2'-Deoxyadenosine monohydrate

T2752

Synonym:

Target: Others, Endogenous Metabolite

1-Methyladenosine

T7571

Synonym:

Target: Endogenous Metabolite

Pseudoginsenoside F11

T3920

Synonym: Ginsenoside A1

Target: Others, Endogenous Metabolite

Ginsenoside Rb3

T3918

Synonym: Gypenoside IV

Target: NF-κB, COX, NO Synthase

Ginsenoside Rd

T2878

Synonym: Panaxoside Rd,Sanchinoside Rd,Gypenoside VIII

Target: P450, Calcium Channel, NF-κB, COX, Endogenous Metabolite

20(S)-Ginsenoside Rg3

T3402

Synonym: 20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3

Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite

20(R)-Ginsenoside Rg2

T3830

Synonym: 20R-Ginsenoside Rg2

Target: Others, NF-κB

Synonym: NSC-141848,NSC141848,NSC 141848

Target: Endogenous Metabolite

Ginsenoside Ro

T3915

Synonym: Chikusetsusaponin 5,Polysciasaponin P3,Chikusetsusaponin V

Target: Calcium Channel, Reductase, Prostaglandin Receptor

N6-(4-Hydroxybenzyl)adenosine

T12164

Synonym: Para-topolin riboside

Target: P2Y Receptor

20-O-Glucoginsenoside Rf

Adenosine 5'-diphosphate

T1723

Synonym: Adenosine diphosphate,adenosine pyrophosphate,ADP

Target: Endogenous Metabolite

Clematichinenoside AR

TN1507

Synonym:

Target: TNF, Autophagy

S-(5'-Adenosyl)-L-methionine tosylate

T4447

Synonym: SAMe,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt

Target: Others

2′-Deoxyadenosine 5′-monophosphate disodium

T40370

Synonym:

Target: Endogenous Metabolite

2-Methyladenosine

TN7208

Synonym: 2-methyl adenosine

Target: Others

Ginsenoside Rf

T6S1500

Synonym: Ginsenoside-Rf,Panaxoside Rf

Target: Calcium Channel, Endogenous Metabolite

Adrenosterone

T2207

Synonym: 11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G

Target: Androgen Receptor, Endogenous Metabolite

Notoginsenoside Fe

T5S1590

Synonym: Notoginseng triterpenes,Ginsenoside Mb

Target: Others

Notoginsenoside R1

T2961

Synonym: Sanqi glucoside R1,Sanchinoside R1

Target: Apoptosis, ERK, Beta Amyloid

Psoralenoside

TN1008

Synonym:

Target: CaMK, Calcium Channel, Histamine Receptor

Adenosine 5'-diphosphate sodium salt

T5079

Synonym: Adenosine-5'-diphosphate trisodium salt,ADP sodium salt

Target: Others, Endogenous Metabolite

2'-O-Methyladenosine

T13482

Synonym:

Target: Endogenous Metabolite

(20R)-Ginsenoside Rg3

T3812

Synonym: 20(R)-Ginsenoside Rg3,(20R)Ginsenoside Rg3,20(R)-Propanaxadiol

Target: Others

Pseudoginsenoside RT5

Target: Others, IFNAR, Interleukin

Ginsenoside Rg2

T2873

Synonym: Chikusetsusaponin I,Panaxoside Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2

Target: Beta Amyloid, GSK-3, NF-κB

Ginsenoside Re

T2872

Synonym: Ginsenoside B2,Panaxoside Re,Chikusetsusaponin Ivc,Sanchinoside Re

Target: Beta Amyloid, NF-κB, Endogenous Metabolite, JNK

Ginsenoside Rh1

T2932

Synonym: Sanchinoside B2,Prosapogenin A2,20(S)-Ginsenoside Rh1,Sanchinoside Rh1

Target: IL Receptor, TNF, Endogenous Metabolite, PPAR, Interleukin

Ginsenoside C-K

T3811

Synonym: Ginsenoside compound K,Ginsenoside K

Target: P450, cell cycle arrest, COX, NO Synthase

20(R)-Ginsenoside Rh2

T3813

Synonym: (20R)Ginsenoside Rh2,Ginsenoside Rh2

Target: Apoptosis, MMP, HSV

Ginsenoside Rb2

T3919

Synonym: Ginsenoside C

Target: GPR, Others, Influenza Virus, Endogenous Metabolite

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-03985	Adenosine Deaminase Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	Adenosine Desaminase (ADA) deficiency, is a purine metabolic disorder that cause severe combined immunodeficiency (SCID) due to the accumulation of toxic metabolites that primarily affects development, differentiation a...
TMPH-02526	Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synth...

Adenosine Deaminase Protein, Human, Recombinant (His)

TMPY-03985

Species: Human

Expression System: Baculovirus Insect Cells

Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02526

Species: Mouse

Expression System: E. coli

カタログ番号	製品名
L2900	Oxidation-Reduction Compound Library		1264 compounds
	1264 small molecule compounds with pro-oxidant or anti-oxidant activity for high-throughput and high-content screening.

ライブラリー

Oxidation-Reduction Compound Library

L2900

Compounds: 1264