Powder: -20°C for 3 years | In solvent: -80°C for 1 year
VUF10460 is a non-imidazole histamine H4 receptor agonist.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
2 mg | 在庫あり | ¥ 7,500 | |||
5 mg | 在庫あり | ¥ 12,000 | |||
10 mg | 在庫あり | ¥ 19,500 | |||
25 mg | 在庫あり | ¥ 38,000 | |||
50 mg | 在庫あり | ¥ 66,000 | |||
100 mg | 在庫あり | ¥ 103,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 13,000 |
説明 | VUF10460 is a non-imidazole histamine H4 receptor agonist. |
ターゲット&IC50 | H4 receptor:7.46(pKi) |
In vitro | UF10460 binds to rat H3 and H4 receptor with pKi values of 5.75, and 7.46, respectively, whereas VUF10460 displays approximately a 50-fold selectivity for the rat H4 receptor over the H3 receptor[1]. |
In vivo | HCl-induced rat gastric lesions is significantly enhanced by the H4 receptor agonists VUF10460. This effect is not modified by H4 receptor antagonist JNJ7777120[1]. VUF10460 displayed approximately a 50-fold selectivity for the rat H(4) receptor over the H(3) receptor. |
分子量 | 269.34 |
分子式 | C15H19N5 |
CAS No. | 1028327-66-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 36 mg/mL
You can also refer to dose conversion for different animals. 詳細
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VUF10460 1028327-66-3 GPCR/G Protein Immunology/Inflammation Neuroscience Histamine Receptor Inhibitor VUF 10460 inhibit VUF-10460 inhibitor