Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Gimatecan HCl (ST1481 HCL) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 9,000 |
2 mg | 在庫あり | ¥ 12,500 |
5 mg | 在庫あり | ¥ 17,000 |
10 mg | 在庫あり | ¥ 28,000 |
25 mg | お問い合わせ | ¥ 45,500 |
50 mg | お問い合わせ | ¥ 68,500 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 22,500 |
説明 | Gimatecan HCl (ST1481 HCL) is a potent topoisomerase I inhibitor. Gimatecan is an orally bioavailable camptothecin analogue with antitumor activity. |
In vitro | Gimatecan HCl (3 to 300 ng/mL) significantly inhibits the growth of human bladder cancer models (HT1376 and MCR), thus reflecting antiproliferative potency. Gimatecan HCl causes a persistent S-phase arrest At 0.003 µg/mL and the number of S-phase cells increased after treatment with a higher concentration (0.03 µg/mL)[1]. |
In vivo | Gimatecan HCl (2 mg/kg; treatment per os, every fourth day for four times) is effective for inhibiting tumor growth [1]. |
別名 | ST1481 HCL, Gimatecan HCl(292618-32-7 Free base) |
分子量 | 483.94 |
分子式 | C25H26ClN3O5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.84 mg/mL (10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Gimatecan HCl DNA Damage/DNA Repair Topoisomerase ST1481 HCL Gimatecan HCl(292618-32-7 Free base) Inhibitor inhibitor inhibit