store at low temperature
store at -80°C
Lexatumumab (GHS-ETR 2) is a human excitatory monoclonal antibody targeting TRAIL receptor 2 that has anticancer activity and induces apoptosis in malignant mesothelioma. Lexatumumab can be used to study malignant pleural mesothelioma (MPM).
説明 | Lexatumumab (GHS-ETR 2) is a human excitatory monoclonal antibody targeting TRAIL receptor 2 that has anticancer activity and induces apoptosis in malignant mesothelioma. Lexatumumab can be used to study malignant pleural mesothelioma (MPM). |
In vitro |
Combining lexatumumab with cisplatin can synergistically inhibit cell growth and enhance apoptosis and death[1]. In different melanoma cell lines, lexatumumab (0-10 μg/ml, 72 h) induced varying degrees of cell death[2]. |
In vivo | Lexatumumab ( 10mg / kg, intravenous injection, twice a week ) combined with Dacarbazine can increase the anti-tumor effect in mice [ 2 ]. |
別名 | ETR2-ST01, DR5 mAB, HGS-ETR 2 |
分子量 | 143.6 (kDa) |
CAS No. | 845816-02-6 |
store at low temperature
store at -80°C
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Lexatumumab 845816-02-6 Apoptosis ETR2-ST01 DR5 mAB HGS-ETR 2 Inhibitor inhibitor inhibit