Powder: -20°C for 3 years | In solvent: -80°C for 1 year
C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
2 mg | 在庫あり | ¥ 8,000 | |||
5 mg | 在庫あり | ¥ 13,000 | |||
10 mg | 在庫あり | ¥ 21,500 | |||
25 mg | 在庫あり | ¥ 43,500 | |||
50 mg | 在庫あり | ¥ 68,500 | |||
100 mg | 在庫あり | ¥ 113,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 14,000 |
説明 | C-4 is a potential ATP-competitive inhibitor of mTOR. C-4 could inhibit cell growth and proliferation. |
In vitro | The addition of C-4 (mTOR inhibitor-1, 0~12.8 μg/ml) directly decreases the level of activated mTOR (p-mTORser2448) which is phosphorylated at Ser2448. The proliferation of A549 cells is strongly inhibited by C-4, and the inhibitory effect is time- and dose314 dependent. The IC50 of C-4 at 24 h is calculated as 3.176 μM. |
分子量 | 363.21 |
分子式 | C16H15BrN2O3 |
CAS No. | 468747-17-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 70 mg/mL (192.72 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
mTOR inhibitor-1 468747-17-3 Autophagy PI3K/Akt/mTOR signaling mTOR mTOR inhibitor1 Mammalian target of Rapamycin inhibit mTOR inhibitor 1 Inhibitor inhibitor