Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM in a reporter assay).1It inhibits RORγt-induced transcription in HEK293T cells expressing the human receptor (IC50= 300 nM). ML-209 inhibits RORγt-dependent differentiation of isolated na?ve cord blood human CD4+T cells into Th17 T helper cells.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 26,000 | |||
5 mg | 在庫あり | ¥ 60,500 | |||
10 mg | 在庫あり | ¥ 79,000 | |||
25 mg | 在庫あり | ¥ 133,000 | |||
50 mg | 在庫あり | ¥ 190,500 | |||
100 mg | 在庫あり | ¥ 264,000 | |||
500 mg | 在庫あり | ¥ 523,500 |
説明 | ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM in a reporter assay).1It inhibits RORγt-induced transcription in HEK293T cells expressing the human receptor (IC50= 300 nM). ML-209 inhibits RORγt-dependent differentiation of isolated na?ve cord blood human CD4+T cells into Th17 T helper cells. |
ターゲット&IC50 | RORγ:1.1 μM |
分子量 | 441.52 |
分子式 | C25H31NO6 |
CAS No. | 1334526-14-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 18.33 mg/mL (41.52 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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ML 209 1334526-14-5 Metabolism ROR ML209 ML-209 Inhibitor inhibitor inhibit