Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Procainamide (Novocainamide) is a specific and potent DNA methyltransferase 1 ( DNMT1 ) inhibitor. Procainamide is a Class 1A antiarrhythmic agent. Procainamide has the potential for the research of cancer and arrhythmias [1] [2].
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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50 mg | 在庫あり | ¥ 7,000 | |||
100 mg | 在庫あり | ¥ 9,000 | |||
200 mg | 在庫あり | ¥ 13,000 | |||
500 mg | 約6-8 週間 | ¥ 21,000 |
説明 | Procainamide (Novocainamide) is a specific and potent DNA methyltransferase 1 ( DNMT1 ) inhibitor. Procainamide is a Class 1A antiarrhythmic agent. Procainamide has the potential for the research of cancer and arrhythmias [1] [2]. |
In vitro | HCT116, HCT116 DNMT1−/−, and HCT116 DNMT3b−/− cells were treated with PBS, pH 7.4 or 0.5 mM procainamide for 96 h. Procainamide treatment of HCT116 DNMT3b−/− cells decreased m5dC content by 11.5%, but treatment of HCT116 DNMT1−/− cells did not decrease m5dC content. These results suggested that DNMT1 was the intracellular target of procainamide[1]. |
別名 | Biocoryl, Novocainamide |
分子量 | 235.33 |
分子式 | C13H21N3O |
CAS No. | 51-06-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (191.2 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Procainamide 51-06-9 Chromatin/Epigenetic DNA Methyltransferase Biocoryl Novocainamide Inhibitor inhibitor inhibit