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Co-inhibitory Immune Checkpoint Proteins

Inhibitory checkpoint molecules play an important role in the maintenance of immune homeostasis: their expression on effector T cells ensures the proper contraction of effector T cell responses; their expression on regulatory T (Treg) cells promotes the suppressive function of Tregs. Blockade of inhibitory immune checkpoint molecules has proven to enhance immune responses to various cancers and exhibit remarkable clinical efficacy in cancer treatment.

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Species
Canine (8)
Cavia porcellus (1)
Cynomolgus (60)
Human (196)
Marmoset (1)
Mouse (80)
Rabbit (2)
Rat (25)
Rhesus (33)
Expression System
Baculovirus Insect Cells (5)
CHO Cells (1)
E. coli (5)
HEK293 Cells (380)
P. pastoris (Yeast) (1)
Tag
Avi (34)
C-6xHis (25)
C-6xHis-Avi (3)
C-Avi (4)
C-Avi-6xHis (5)
C-Fc (1)
C-Flag (3)
C-GST (1)
C-His (95)
C-His-Avi (27)
C-hFc (87)
C-hFc-6xHis (2)
C-hFc-Avi (8)
C-mFc (16)
C-rFc (2)
His (60)
N-6xHis-Flag (1)
N-8xHis (1)
N-Flag (7)
N-GST (2)
N-His-Avi (7)
N-hFc (2)
N-hFc-Flag (1)
Tag Free (12)
hFc (31)
カタログ番号 製品名 / Synonyms Species Expression System
TMPY-06074 B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)
Cynomolgus,Rhesus HEK293 Cells
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the acce...
TMPY-04348 CTLA-4 Protein, Human, Recombinant (His)
CTLA-4 Protein, Human, Recombinant (His)
Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number i...
TMPY-06978 TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated
TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated
Mouse HEK293 Cells
TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 16.01 ...
TMPY-06977 PD-L1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
PD-L1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Mouse HEK293 Cells
PD-L1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.02 ...
TMPY-06966 Siglec-9 Protein, Human, Recombinant (His & hFc)
Siglec-9 Protein, Human, Recombinant (His & hFc)
Human HEK293 Cells
Siglec-9 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 64.13 kDa and the...
TMPY-06931 LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Human HEK293 Cells
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 74.73 ...
TMPY-06930 BTLA Protein, Human, Recombinant (isoform1,hFc)
BTLA Protein, Human, Recombinant (isoform1,hFc)
Human HEK293 Cells
BTLA Protein, Human, Recombinant (isoform1,hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.47 kDa and the accessio...
TMPY-06923 BTLA Protein, Mouse, Recombinant (His)
BTLA Protein, Mouse, Recombinant (His)
Mouse HEK293 Cells
BTLA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.54 kDa and the accession number ...
TMPY-06922 BTLA Protein, Human, Recombinant (isoform1, His)
BTLA Protein, Human, Recombinant (isoform1, His)
Human HEK293 Cells
BTLA Protein, Human, Recombinant (isoform1, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.19 kDa and the accessi...
TMPY-06913 BTLA Protein, Human, Recombinant (His & Avi), Biotinylated
BTLA Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
BTLA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17 kDa....
TMPY-06909 B7-1 Protein, Rat, Recombinant (His)
B7-1 Protein, Rat, Recombinant (His)
Rat HEK293 Cells
B7-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.38 kDa and the accession number is...
TMPY-06907 CD73 Protein, Human, Recombinant (His & Avi), Biotinylated
CD73 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
CD73 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 61.04 k...
TMPY-06894 VISTA Protein, Human, Recombinant (His & Avi), Biotinylated
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 21.41 ...
TMPY-06880 CD86 Protein, Human, Recombinant (His & Avi), Biotinylated
CD86 Protein, Human, Recombinant (His & Avi), Biotinylated
Human HEK293 Cells
CD86 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.42 k...
TMPY-06847 Siglec-9 Protein, Human, Recombinant (His)
Siglec-9 Protein, Human, Recombinant (His)
Human HEK293 Cells
Siglec-9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.48 kDa and the accession num...
TMPY-06838 PD-L2 Protein, Rhesus, Recombinant (His)
PD-L2 Protein, Rhesus, Recombinant (His)
Rhesus HEK293 Cells
PD-L2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number i...
TMPY-06829 BTLA Protein, Human, Recombinant (isoform 1,mFc)
BTLA Protein, Human, Recombinant (isoform 1,mFc)
Human HEK293 Cells
BTLA Protein, Human, Recombinant (isoform 1,mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.56 kDa and the accessi...
TMPY-06824 CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 42.89...
TMPY-06819 PD-L2 Protein, Rhesus, Recombinant (hFc)
PD-L2 Protein, Rhesus, Recombinant (hFc)
Rhesus HEK293 Cells
PD-L2 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.6 kDa and the accession number...
TMPY-06772 IDO Protein, Mouse, Recombinant (His)
IDO Protein, Mouse, Recombinant (His)
Mouse E. coli
IDO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.47 kDa and the accession numbe...
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-06074
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the acce...
CTLA-4 Protein, Human, Recombinant (His)
TMPY-04348
CTLA-4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15 kDa and the accession number i...
TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06978
TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 16.01 ...
PD-L1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPY-06977
PD-L1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.02 ...
Siglec-9 Protein, Human, Recombinant (His & hFc)
TMPY-06966
Siglec-9 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 64.13 kDa and the...
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06931
LAG-3 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 74.73 ...
BTLA Protein, Human, Recombinant (isoform1,hFc)
TMPY-06930
BTLA Protein, Human, Recombinant (isoform1,hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.47 kDa and the accessio...
BTLA Protein, Mouse, Recombinant (His)
TMPY-06923
BTLA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.54 kDa and the accession number ...
BTLA Protein, Human, Recombinant (isoform1, His)
TMPY-06922
BTLA Protein, Human, Recombinant (isoform1, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.19 kDa and the accessi...
BTLA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06913
BTLA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17 kDa....
B7-1 Protein, Rat, Recombinant (His)
TMPY-06909
B7-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.38 kDa and the accession number is...
CD73 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06907
CD73 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 61.04 k...
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06894
VISTA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 21.41 ...
CD86 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06880
CD86 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 28.42 k...
Siglec-9 Protein, Human, Recombinant (His)
TMPY-06847
Siglec-9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.48 kDa and the accession num...
PD-L2 Protein, Rhesus, Recombinant (His)
TMPY-06838
PD-L2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number i...
BTLA Protein, Human, Recombinant (isoform 1,mFc)
TMPY-06829
BTLA Protein, Human, Recombinant (isoform 1,mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 40.56 kDa and the accessi...
CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TMPY-06824
CTLA-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 42.89...
PD-L2 Protein, Rhesus, Recombinant (hFc)
TMPY-06819
PD-L2 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.6 kDa and the accession number...
IDO Protein, Mouse, Recombinant (His)
TMPY-06772
IDO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 46.47 kDa and the accession numbe...
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