ホーム 計算ツール
代理店ログイン

検索結果

Search Results for " 26S "

ターゲット

14

阻害剤

19

リコンビナントタンパク質

1

ライブラリー

カタログ番号 製品名 別名 ターゲット
T7814 Alloxan monohydrate Proteasome
Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.
T2154 MG-132 Z-LLL-al,Z-Leu-Leu-Leu-CHO Apoptosis , Proteasome , Autophagy
MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor (IC50=100 nM) that is cell-permeable and reversible. MG-132 acts as an autophagy activator and also induces apoptosis.
T78353 Alpha-2,6-Sialyltransferase (Pd26ST)
Alpha-2,6-Sialyltransferase (Pd26ST) efficiently catalyzes the sialylation of both terminal and internal galactose and N-acetylgalactosamine residues, resulting in the production of terminal α2,6-sialosides [1].
T9090 MUN57694 Proteasome
MUN57694 is an inhibitor of 26S proteasome.
T1932 B-AP15 NSC 687852 Apoptosis , DUB
B-AP15 (NSC-687852)(NSC-687852) is a selective inhibitor of the deubiquitinating enzymes Usp14 and UCHL5 of the 26S proteasome. It blocks the deubiquitinating activity of the 26S proteasome.
T36902 RA375 RA375 Proteasome
RA375, an inhibitor of RPN13 (26S proteasome regulatory subunit), enhances UPR signaling, ROS production, and apoptosis. Demonstrating ten times the efficacy against cancer lines compared to RA190, RA375 owes its increas...
T60487 DDO-7263 Nrf2
DDO-7263 is a 1,2,4-Oxadiazole derivative that upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 is a potent Nrf2 activator th...
T21617 MG-115 Z-LL-Nva-CHO Proteasome
MG-115 (Z-LL-Nva-CHO) is a potent and reversible inhibitor of proteasome , with K i s of 21 nM and 35 nM for 20S and 26S proteasome, respectively. MG-115 specifically inhibit the chymotrypsin-like activity of the proteas...
T37011 Boc-LRR-AMC
Boc-LRR-AMC is a fluorogenic substrate for the trypsin-like activity of the 26S proteasome or 20S proteolytic core. Upon enzymatic cleavage by the 26S proteasome or 20S proteolytic core, amino-4-methylcoumarin (AMC) is r...
T76038 Ac-Nle-Pro-Nle-Asp-AMC
Ac-Nle-Pro-Nle-Asp-AMC is a specific substrate for the 26S proteasome and is utilized in analyzing the proteasome's caspase-like activity [1] [2] [3].
T77939 WBC100 14-D-Valine-TPL c-Myc
WBC100 (14-D-Valine-TPL) is a potent, selective, and orally active c-Myc glue degrader that targets the ubiquitin E3 ligase CHIP-mediated 26S proteasome pathway, primarily utilized in research for c-Myc overexpressing tu...
T37417 Z-LLE-AMC
Z-LLE-AMC is a fluorogenic substrate for the caspase-like post-glutamate peptide hydrolase of the 26S proteasome or 20S proteolytic core. Caspase-like activity can be quantified by fluorescent detection of free AMC (also...
T37418 Z-LLL-AMC
Z-LLL-AMC is a fluorogenic substrate for the chymotrypsin-like activity of the 26S proteasome or 20S proteolytic core. Chymotrypsin-like activity can be quantified by fluorescent detection of free AMC (also known as 7-am...
T62080 GSK3494245
GSK3494245 (DDD01305143) is a potent, selective, orally active inhibitor of chymotrypsin-like activity that binds to the proteasome of WTL.donovani at an IC50 of 0.16 μM, sandwiched between the β4 and β5 subunits. GSK349...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPJ-00703 Gankyrin Protein, Human, Recombinant Human E. coli
Gankyrin is a multicatalytic proteinase oncoprotein consists of 7 ankyrin repeats. Gankyrin overexpressed in most hepatocellular carcinomas. Gankyrin is involved in theregulation of the phosphorylation of the retinoblast...
TMPY-06429 SARS-CoV-2 Spike S1+S2 Protein (P26S, 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H & T1027I & D1118H, His) SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (P26S, 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H & T1027I & D1118H, His) is expressed in Baculovirus insect cells with His tag. The p...
TMPY-06420 SARS-CoV-2 Spike S1 Protein (P26S & 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H, His) SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (P26S & 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular wei...
TMPY-06159 SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I & V1176F, His) SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I & V1176F, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is ...
TMPY-06268 SARS-CoV-2 Spike S1 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y, His & Avi), Biotinylated SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weigh...
TMPY-06131 SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I, His) SARS-CoV-2 Baculovirus Insect Cells
SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 134.4 kDa...
TMPY-06136 SARS-CoV-2 Spike S1 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y, His) SARS-CoV-2 HEK293 Cells
SARS-CoV-2 Spike S1 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.5 kDa and the access...
TMPH-02250 TPP2 Protein, Human, Recombinant (His & Myc) Human Baculovirus Insect Cells
Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter ...
TMPH-02953 TPP2 Protein, Mouse, Recombinant (His & Myc) Mouse Baculovirus Insect Cells
Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter ...
TMPH-03762 TPP2 Protein, Mouse, Recombinant (E. coli, His & Myc) Mouse E. coli
Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter ...
TMPH-03757 TPP2 Protein, Human, Recombinant (E. coli, His & Myc) Human E. coli
Component of the proteolytic cascade acting downstream of the 26S proteasome in the ubiquitin-proteasome pathway. May be able to complement the 26S proteasome function to some extent under conditions in which the latter ...
TMPH-02284 USP26 Protein, Human, Recombinant (His) Human E. coli
Involved in the ubiquitin-dependent proteolytic pathway in conjunction with the 26S proteasome. Deubiquitinates the androgen receptor and regulates the androgen receptor signaling pathway.
TMPY-00607 PSMB6 Protein, Mouse, Recombinant (His) Mouse E. coli
PSMB6 subunit belongs to the 20S proteasomal subunit family, which plays an importance role in the antigen presentation by MHC class I molecular. Proteasome subunit beta type 6 (PSMB6) is a member of 20S proteasomal subu...
TMPH-01522 HIV-2 (subtype A, isolate ROD) Protein Vpx (His) HIV-2 P. pastoris (Yeast)
Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by...
TMPJ-01013 VCP Protein, Human, Recombinant (His) Human E. coli
Valosin-Containing Protein (VCP) is a nuclear protein that belongs to the AAA ATPase family. VCP is a putative ATP-binding protein involved in vesicle transport and fusion, 26S proteasome function, and assembly of peroxi...
TMPH-02300 RAD23A Protein, Human, Recombinant (His) Human E. coli
Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chain...
TMPY-03614 PSME3 Protein, Human, Recombinant (His) Human E. coli
PSME3, also known as PA28-gamma, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is comp...
TMPY-03612 PSME1 Protein, Human, Recombinant (His) Human E. coli
PA28A, also known as PSME1, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed ...
TMPY-03610 PSME2 Protein, Human, Recombinant (His) Human E. coli
PSME2, also known as PA28b, is a subunit of proteasome. The 26S proteasome multicatalytic proteinase complex has a highly ordered structure composed of 2 complexes, a 2S core and a 19S regulator. The 2S core is composed ...
Gankyrin Protein, Human, Recombinant
TMPJ-00703
Species: Human
Expression System: E. coli
SARS-CoV-2 Spike S1+S2 Protein (P26S, 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H & T1027I & D1118H, His)
TMPY-06429
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1 Protein (P26S & 69-70 deletion & V126A & Y144 deletion & 241-243 deletion & H245Y & S477N & E484K & D614G & P681H, His)
TMPY-06420
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I & V1176F, His)
TMPY-06159
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y, His & Avi), Biotinylated
TMPY-06268
Species: SARS-CoV-2
Expression System: HEK293 Cells
SARS-CoV-2 Spike S1+S2 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y & T1027I, His)
TMPY-06131
Species: SARS-CoV-2
Expression System: Baculovirus Insect Cells
SARS-CoV-2 Spike S1 Protein (L18F & T20N & P26S & D138Y & R190S & K417T & E484K & N501Y & D614G & H655Y, His)
TMPY-06136
Species: SARS-CoV-2
Expression System: HEK293 Cells
TPP2 Protein, Human, Recombinant (His & Myc)
TMPH-02250
Species: Human
Expression System: Baculovirus Insect Cells
TPP2 Protein, Mouse, Recombinant (His & Myc)
TMPH-02953
Species: Mouse
Expression System: Baculovirus Insect Cells
TPP2 Protein, Mouse, Recombinant (E. coli, His & Myc)
TMPH-03762
Species: Mouse
Expression System: E. coli
TPP2 Protein, Human, Recombinant (E. coli, His & Myc)
TMPH-03757
Species: Human
Expression System: E. coli
USP26 Protein, Human, Recombinant (His)
TMPH-02284
Species: Human
Expression System: E. coli
PSMB6 Protein, Mouse, Recombinant (His)
TMPY-00607
Species: Mouse
Expression System: E. coli
HIV-2 (subtype A, isolate ROD) Protein Vpx (His)
TMPH-01522
Species: HIV-2
Expression System: P. pastoris (Yeast)
VCP Protein, Human, Recombinant (His)
TMPJ-01013
Species: Human
Expression System: E. coli
RAD23A Protein, Human, Recombinant (His)
TMPH-02300
Species: Human
Expression System: E. coli
PSME3 Protein, Human, Recombinant (His)
TMPY-03614
Species: Human
Expression System: E. coli
PSME1 Protein, Human, Recombinant (His)
TMPY-03612
Species: Human
Expression System: E. coli
PSME2 Protein, Human, Recombinant (His)
TMPY-03610
Species: Human
Expression System: E. coli
カタログ番号 製品名
L8600 Ubiquitination Compound Library

210 compounds
A unique collection of 210 ubiquitination related small chemicals can be used for high throughput and high content screening;