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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T12352 | Oxidopamine hydrochloride | 6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride | Mitophagy , Dopamine Receptor , Autophagy |
Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist. | |||
T12352L | Oxidopamine hydrobromide | 6-Hydroxydopamine hydrobromide,6-OHDA hydrobromide | Mitophagy , Dopamine Receptor , Autophagy |
Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist. | |||
T40951 | ABT-107 | ||
ABT-107, a selective α7 neuronal nicotinic receptor agonist, demonstrates neuroprotective effects against nigrostriatal damage in rats with unilateral 6-hydroxydopamine lesions. | |||
T28793 | SKF-80723 HBr | SKF80723 Hydrobromide,SKF 80723 HBr,SKF-80723 Hydrobromide,SKF 80723 Hydrobromide | |
SKF-80723 HBr is a D1 receptor agonist. SKF-80723 HBr strongly potentiated the contralateral circling induced by quinpirole in rats with a unilateral 6-hydroxydopamine (6-OHDA) lesion of the medial forebrain bundle. | |||
T27959 | LY503430 | LY-503430,LY 503430 | |
LY503430 is a AMPA receptor potentiator with oral activity. LY503430 has both nootropic and neuroprotective effects, reducing brain damage caused by 6-hydroxydopamine or MPTP. | |||
T33858 | PACA | N-Propargyl Caffeamide | |
PACA, (N-propargyl Caffeamide)enhances NGF-induced neurite growth and reduces 6-hydroxydopamine neurotoxicity in neuron cultures. Parkinson's disease (PD) is associated with insufficient production of nerve growth factor... | |||
T20396 | Levadopa Related Compound A | 6-Hydroxydopa, L-,L-Hydroxydopa | |
Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent... |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN1644 | Flavanomarein | Others | |
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea... | |||
T27012 | Chrysotoxine | Phenol, 4-[2-(3,4-dimethoxyphenyl)ethyl]-2,6-dimethoxy-,4-[2-(3,4-Dimethoxyphenyl)ethyl]-2,6-dimethoxyphenol | NF-κB |
Chrysotoxine (Phenol, 4-[2-(3,4-dimethoxyphenyl)ethyl]-2,6-dimethoxy-) inhibits 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via NF-κB modulation and mitochondria protection. | |||
T5S2357 | Acetylcorynoline | (+)-Corynoline Acetate,O-Acetylcorynoline | Antifungal |
1. Acetylcorynoline (O-Acetylcorynoline) has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of dendritic cells maturation and function. 3... | |||
T3803 | Specnuezhenide | Nuzhenide,Nuezhenide | Others , NF-κB , Wnt/beta-catenin |
Specnuezhenide (Nuezhenide) significantly protects human neuroblastoma SH-SY5Y cells from 6-hydroxydopamine-induced neurotoxicity.Nuezhenide is the main inhibitory compound of fruits, it shows a clear inhibitory effect t... | |||
T82058 | Inubritannolide A | ||
Inubritannolide A exhibits moderate to robust neuroprotective effects across various neuronal cell types against inducers such as H2O2, 6-hydroxydopamine (6-OHDA), and lipopolysaccharide (LPS). | |||
TN1653 | Fustin | ERK , Beta Amyloid , AChR | |
Fustin is the phytogenic flavanol component of the plant Rhus verniciflua Stokes. Fustin shows protective effects on 6-hydroxydopamine-induced neuronal cell death. |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPJ-00827 | Tau-D Protein, Human, Recombinant (His) | Human | E. coli |
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. ... | |||
TMPK-00614 | NKp46/NCR1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse... | |||
TMPY-02705 | NRG1 beta 1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
NRG1 beta 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 55.2 kDa and the accession number is Q02297-6. | |||
TMPY-04277 | CD45 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6. | |||
TMPY-03010 | NRG1 beta 1 Protein, Human, Recombinant | Human | HEK293 Cells |
NRG1 beta 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297-6. | |||
TMPJ-00567 | NCR1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is... | |||
TMPY-02600 | NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) | Human | HEK293 Cells |
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 36.7 kDa and the accession number is Q02297-6. | |||
TMPY-05798 | VEGF145 Protein, Human, Recombinant | Human | HEK293 Cells |
VEGF145 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16.92 kDa and the accession number is P15692-6. | |||
TMPY-03128 | LAIR1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
LAIR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is Q8BG84-6. | |||
TMPK-00615 | NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse... | |||
TMPK-01364 | SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01358 | SIRP alpha V6 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... |