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T1272L |
Cytarabine hydrochloride
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Ara-C hydrochloride,Cytosine Arabinoside hydrochloride |
DNA/RNA Synthesis
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Cytarabine hydrochloride (Ara-C hydrochloride) is a nucleoside analog that causes S phase cell cycle arrest and inhibits DNA polymerase. Cytarabine inhibits DNA synthesis with an IC 50 of 16 nM. Cytarabine hydrochloride ... |
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TNU1176 |
2’-Fluoro-2’-deoxy-ara-C(Bz)-3’-phosphoramidite
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2'-Fluoro-2'-deoxy-ara-C(Bz)-3'-phosphoramidite is a Nucleoside Phosphoramidite; Nucleoside Derivative - Fluoro-modified nucleoside. |
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TP1828 |
N-Acetyl-Ser-Asp-Lys-Pro
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RAAS
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Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethalit... |
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T8308 |
NL-1
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Mitochondrial Metabolism
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Autophagy
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NL-1 is a mitoNEET inhibitor with antileukemic effect. |
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T36944 |
Ara-G
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Nucleoside Antimetabolite/Analog
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Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporate... |
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T11957 |
MBC-11 trisodium
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Others
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MBC-11 trisodium has potential to treat tumor-induced bone disease (TIBD).It is a first-in-class conjugate of the bone-targeting bisphosphonate HEDP covalently linked to the antimetabolite Ara-C. |
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T17059 |
Tetrahydrouridine
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NSC 112907,NSC112907,NSC-112907 |
DNA Methyltransferase
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Tetrahydrouridine (NSC-112907; THU) is a multidrug resistance modulator. It can be used in cancer treatment to make tumor cells more sensitive to radiation therapy. THU is a competitive cytidine deaminase(CDA) inhibitor ... |
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T71361 |
CHS-828 nicotinate
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CHS-828 nicotinate is a CHS-828 salt with Nicotinic acid.. CHS-828 also known as GMX-1778, is a potent and selective NAMPT inhibitor. CHS-828 inhibits cellular synthesis of NAD. CHS 828 kill tumour cells by inhibiting ... |
