Butin | TargetMol

カタログ番号	製品名	別名	ターゲット
T1197	Trimebutine maleate	Debridat,Polibutin	Calcium Channel , Opioid Receptor
	Trimebutine maleate (Polibutin) is a weak mu-opioid agonist and has antimuscarinic effects. Trimebutine is an agonist of peripheral mu, delta, and kappa opiate receptors served as a spasmolytic drug for therapy of both c...		Calcium Channel , Opioid Receptor
T1501	Rifabutin	LM-427,Ansamycin	HSP , DNA/RNA Synthesis , Antibacterial , Antibiotic
	Rifabutin (LM-427) inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription. Rifabutin is a semisynthetic ansamycin...		HSP , DNA/RNA Synthesis , Antibacterial , Antibiotic
T27413	Trimebutine CTB salt	GIC1001	Opioid Receptor
	Trimebutine CTB salt (GIC-1001) is an opioid receptor agonist used in the study of pain.		Opioid Receptor
T0918	Trimebutine	Mebutin	Opioid Receptor
	Trimebutine (Mebutin) is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu-opioid agonist effects. It is marketed for the treatment of irritabl...		Opioid Receptor
T78523	Clobutinol hydrochloride		Potassium Channel
	Clobutinol hydrochloride, an antitussive agent, influences heart rate and blood pressure, and is utilized in cough-related research [1] [2] [3].		Potassium Channel
T60393	Clobutinol
	Clobutinol has anti-tussive effects. Clobutinol affects heart rate and blood pressure, it can be used for cough related research [1] [2] [3].
T18328	MC-Val-Cit-PAB-rifabutin		Others
	MC-Val-Cit-PAB-rifabutin is a drug-linker conjugate designed for antibody-drug conjugates (ADC), featuring the potent antitumor agent rifabutin (a DNA-dependent RNA polymerase inhibitor) connected through the MC-Val-Cit-...		Others
T83924	(R)-(+)-Deoxyarbutin
	(R)-(+)-Deoxyarbutin, an isomer of deoxyarbutin, acts as a tyrosinase inhibitor. Effective at a concentration of 21 µM, it diminishes tyrosinase activity and has been demonstrated to lighten the skin in hairless guinea p...
T83925	(S)-(–)-Deoxyarbutin
	(S)-(–)-Deoxyarbutin, an isomer of deoxyarbutin, functions as a tyrosinase inhibitor, effectively inhibiting tyrosinase activity at a concentration of 74 µM.
T71072	Hexbutinol methiodide
	Hexbutinol methiodide is an inhibitor of muscarinic receptors.
T71315	Hexbutinol
	Hexbutinol is an inhibitor of muscarinic receptors.
T69481	Clanobutin
	Clanobutin inhibits gluconeogenesis and acts as a choleretic and digestion-stimulating agent.

Compounds

Trimebutine maleate

T1197

Synonym: Debridat,Polibutin

Target: Calcium Channel, Opioid Receptor

Rifabutin

T1501

Synonym: LM-427,Ansamycin

Target: HSP, DNA/RNA Synthesis, Antibacterial, Antibiotic

Trimebutine CTB salt

T27413

Synonym: GIC1001

Target: Opioid Receptor

Trimebutine

T0918

Synonym: Mebutin

Target: Opioid Receptor

Clobutinol hydrochloride

T78523

Synonym:

Target: Potassium Channel

MC-Val-Cit-PAB-rifabutin

Hexbutinol methiodide

カタログ番号	製品名	別名	ターゲット
T10637	Butin		Others
	Butin, a major biologically active flavonoid isolated from the Dalbergia odorifera, has strong antioxidant, anti-inflammatory and antiplatelet activities.		Others
TN1461	(-)-Butin	Butin	Akt , PI3K , Nrf2
	(-)-Butin (Butin) has antioxidant activity, can protect cells against H2O2-induced apoptosis, oxidative DNA damage and oxidative mitochondrial dysfunction; it attenuates oxidative stress by activating Nrf2-mediated Mn SO...		Akt , PI3K , Nrf2
T4911	α-Arbutin	4-hydroxyphenyl-D-lucopyranoside,alpha-Arbutoside,alpha-Arbutin	Tyrosinase
	α-Arbutin (4-hydroxyphenyl-D-lucopyranoside) is a synthetic and functional active ingredient for skin lightening.		Tyrosinase
T19898	Methylarbutin	ß-PMP-Glc;4-Methoxyphenyl β-D-Glucopyranoside,ß-PMP-Glc,4-Methoxyphenyl β-D-Glucopyranoside	Others
	Methylarbutin (ß-PMP-Glc;4-Methoxyphenyl β-D-Glucopyranoside) is an ice recrystallization inhibitor (IRI)		Others
T0473	Arbutin	Uva,p-Arbutin,p-Arbutin,β-Arbutin	Tyrosinase
	Arbutin (p-Arbutin)(β-Arbutin) is a glycosylated hydroquinone extracted from the bearberry plant in the genus Arctostaphylos and can inhibit tyrosinase and thus prevent the formation of melanin.		Tyrosinase
T6463	Deoxyarbutin		Tyrosinase
	DeoxyArbutin(IC50=50 nM) inhibits tyrosinase activity reversibly.		Tyrosinase
TN1738	Homoarbutin		Others
	Homoarbutin is a natural product		Others
TN4297	Isohomoarbutin		Others
	Isohomoarbutin is a natural product from the whole herb of Pyrola rotundifolia (Pyrolaceae).		Others
TN1320	6-O-Caffeoylarbutin		Others
	6'-O-caffeoylarbutin may serve as a skin-whitening ingredient with the merits of potent melanin inhibition,less toxicity and reversible melanin synthesis after stopping use.		Others