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ターゲット

阻害剤

天然化合物

カタログ番号	製品名	別名	ターゲット
T30686	Cafedrine	l-Cafedrine,Cafedrin	Others
	Cafedrine (Cafedrin) is found in tea and coffee and has a central nervous system stimulant effect.Cafedrine is often used in fixed 20:1 combination with cortisone in the study of acute hypotension.Cefetamet sodium (Cefet...		Others
TN7093	N-Caffeoyltryptophan	trans-Caffeoyl-L-tryptophan	Sirtuin
	N-Caffeoyltryptophan (trans-Caffeoyl-L-tryptophan), a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 34μM).		Sirtuin
T68641	Kahweol Acetate
	Kahweol Acetate is a semi-synthetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing ...
T71480	Kahweol linoleate
	Kahweol linoleate is a semi-syntetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing...
T71479	Kahweol oleate
	Kahweol oleate is emi-syntetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing cell ...
T83929	(+)-JQ1 maleimide
	(+)-JQ1 maleimide, featuring a cysteine-reactive maleimide linked to the BRD4 ligand, JQ1, via a PEG2 linker, serves as a probe suitable for the COFFEE method (COvalent Functionalization Followed by E3 Electroporation). ...
T68642	Kahweol palmitate
	Kahweol palmitate is a semi-synthetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducin...
T71478	Kahweol stearate
	Kahweol stearate is a semi-synthetic derivative of kahweol, a natural product found in coffee beans. It exhibits a wide variety of biological activities, including inhibiting RANKL-induced osteoclast generation, inducing...
T37476	Cyclo(L-Phe-L-Val)
	Cyclo(L-Phe-L-Val) is a metabolite of the sponge bacterium Pseudoalteromonas sp. NJ6-3-1 that can autoinduce production of antibacterial substances active against S. aureus when co-cultured at a low cell density. It indu...

Compounds

Cafedrine

T30686

Synonym: l-Cafedrine,Cafedrin

Target: Others

N-Caffeoyltryptophan

TN7093

Synonym: trans-Caffeoyl-L-tryptophan

カタログ番号	製品名	別名	ターゲット
T4024	Norharmane	2-Azacarbazole,2,9-Diazafluorene,β-Carboline	DNA , Endogenous Metabolite , Monoamine Oxidase
	Norharmane (β-Carboline) is a natural β-carboline first isolated from plants of the Zygophyllaceae family.		DNA , Endogenous Metabolite , Monoamine Oxidase
T37705	1,2,4-Trihydroxybenzene	Benzene-1,2,4-triol	Calcium Channel
	1,2,4-Trihydroxybenzene (Benzene-1,2,4-triol) is a by-product of coffee bean roasting and is found in mouse, arabica coffee.1,2,4-Trihydroxybenzene is a benzotriol that increases Ca2+ concentration in rat thymic lymphocy...		Calcium Channel
TN7073	3-Feruloyl-4-caffeoylquinic acid		Others
	3-Feruloyl-4-caffeoylquinic acid is a chlorogenic acid isomer. Chlorogenic acids are relevant coffee quality markers, taste, and aroma precursors as well as important bioactive compounds.		Others
T2927	Trigonelline chloride	Gynesine Hydrochloride,Coffearine Hydrochloride,Nicotinic acid N-methylbetaine Hydrochloride,Trigonelline hydrochloride	Others , Antibacterial , Antifungal , HSV
	Trigonelline chloride (Coffearine Hydrochloride), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.		Others , Antibacterial , Antifungal , HSV
TCP2934	5-Methylfurfural	5-Methyl furfural,5-Methyl-2-furaldehyde	Others
	5-Methylfurfural (5-Methyl-2-furaldehyde) has been identified as one of the volatile flavor compounds in tamarind, Dutch Coffee, barrel-aged wines and deep fat-fried soybeans.		Others
T2887	Trigonelline	Trigenolline	Apoptosis , Others , Ferroptosis , Endogenous Metabolite
	Trigonelline (Trigenolline), an alkaloid with potential antidiabetic activity, is present in considerable amounts in coffee.		Apoptosis , Others , Ferroptosis , Endogenous Metabolite
T3158	Harmane	Loturine,Harman,Aribine	Adrenergic Receptor , Monoamine Oxidase , Imidazoline Receptor
	Harmane (Loturine) is a bio-active β-Carboline and monoamine oxidase inhibitor found in coffee and tobacco smoke.
T3791	Atractyloside A		AChR
	Atractyloside is a glycoside of a kaurene type diterpene that is found in some plants including Atractylis gummifera (ATRACTYLIS); COFFEE; XANTHIUM, and CALLILEPIS. Toxicity is due to inhibition of adenine nucleotide tra...		AChR
T67302	2,3-Pentanedione	Acetylpropionyl	Others
	2,3-Pentanedione is a food additive that also occurs naturally as a fermentation product in beer, wine and yogurt and is released during the roasting of coffee beans. Inhalation of 2,3-Pentanedione is thought to be the c...		Others
T38248	2-Ethylpyrazine		Endogenous Metabolite , NO Synthase
	2-Ethylpyrazine is present in roasted coffee beans and is a volatile compound .2-Ethylpyrazine induces vasodilation through the activity of endothelium-derived relaxing factors.2-Ethylpyrazine activates NO synthesis thro...		Endogenous Metabolite , NO Synthase
T20602	2-Acetyl-5-methylthiophene	Methylthienylcetone
	2-Acetyl-5-methylthiophene is a component of coffee aroma.
T83444	16-O-Methylcafestol
	16-O-Methylcafestol, a cafestol derivative, is isolatable from green coffee beans [1].
TN7031	4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one	Caramel Furanone,Fenugreck Lactone,Sotolone	Others
	4,5-Dimethyl-3-hydroxy-2,5-dihydrofuran-2-one (Fenugreck Lactone) is a kind of food spice mainly used in caramel, brown sugar, whisky, marshmallow, coffee, toffee and other flavors.		Others