ペプチド
抗体
色素試薬
PROTAC
バーチャルスクリーニング
TargetMolキット
Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
天然化合物
フェノール類
アルカロイド類
フラボノイド類
阻害剤
血管新生
アポトーシス
オートファジー
細胞周期・チェックポイント
クロマチン・エピジェネティック
細胞骨格シグナル
DNA損傷・DNA修復
内分泌・ホルモン
GPCR/Gタンパク質
免疫・炎症
JAK・STATシグナル
| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T9320 | YK-3-237 | 1215281-19-8 | 98% |
|
| YK-3-237 reduces acetylation of mtp53 and exhibits anti-proliferative effects toward triple-negative breast cancer (TNBC) cells carrying mtp53. | ||||
| T64529 | MDL-800 | 2275619-53-7 | 98% |
|
| MDL-800 is a SIRT6 modulator with antitumor activity for the study of hepatocellular carcinoma and non-small cell lung cancer. | ||||
| T7058 | Selisistat S-enantiomer | 848193-68-0 | 98% |
|
| EX-527 S-enantiomer is the S-enantiomer of EX-527, with an IC50 of 123 nM for SIRT1. EX-527 S-enantiomer is much more potent than EX-527 R-enantiomer. | ||||
| T60064 | WAY-270360 | 476633-98-4 | 98% |
|
| WAY-270360 is a sirtuin modulator and an epidermal growth factor receptor (EGFR) inhibitor. | ||||
| TN1296 | 5-Feruloylquinic acid | 40242-06-6 | 98% |
|
| 5-O-Feruloylquinic acid is a potent Sirt1 agonist, it is a potential lead compound that can be further tested in drug development process for diseases associated... | ||||
| T9998 | 4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]- | 129544-85-0 | 98% |
|
| 4H-1,2,4-Triazole, 3-(phenoxymethyl)-4-phenyl-5-[(phenylmethyl)thio]- is an inhibitor of SIRT2 with antitumor activity. | ||||
| TN7093 | N-Caffeoyltryptophan | 109163-69-1 | 98% |
|
| N-Caffeoyltryptophan, a potential Sirt inhibitor, is screened using coffee extract. N-Caffeoyltryptophan inhibited Sirt2 (IC50; 8.7 μM) better than Sirt1(IC50; 3... | ||||
| T77653 | Z26395438 | 2803-63-6 | 98% |
|
| Z26395438 is an inhibitor of Sirtuin-1 with IC50 of 1.6 μM. | ||||
| T77605 | WAY-323061 | 550301-63-8 | 98% |
|
| WAY-323061 is a SIRT2 inhibitor. | ||||
| T60001 | Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl) | 863589-52-0 | 98% |
|
| Benzamide, 3-methoxy-N-(3-thiazolo[5,4-b]pyridin-2-ylphenyl) is a sirtuin modulator and useful for increasing the lifespan of a cell, and treating and/or preven... | ||||
| T50080 | MC2184 | 74901-20-5 | 98% |
|
| MC2184 is the inhibitor of human recombinant SIRT1. | ||||
| T12918 | SIRT-IN-1 | 1431411-60-7 | 98% |
|
| SIRT-IN-1 is a potent SIRT1/2/3 inhibitor(IC50s of 15, 10, 33 μM, respectively). | ||||
| T22595 | B2 | 115687-05-3 | 98% |
|
| Promotes inclusion formation in cellular models of Huntington's disease and Parkinson's disease | ||||
| T12922 | Sirtuin modulator 1 | 2070015-26-6 | 98% |
|
| Sirtuin modulator 1 is a modulator of SIRT1 with EC1.5 of < 1 μM. | ||||
| T77697 | BML-278 | 120533-76-8 | 98% |
|
| BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, and can... | ||||
| T62515 | SIRT2-IN-9 | 522650-91-5 | 98% |
|
| SIRT2-IN-9 is a selective SRIT2 inhibitor with an IC50 value of 1.3 μM.SIRT2-IN-9 inhibits the proliferation of MCF-7 breast cancer cells.SIRT2-IN-9 can be used ... | ||||
| T2750 | Ginkgolide C | 15291-76-6 | 98% |
|
| Ginkgolide C, a natural product, can enhance the cardiac function of rats in the body. | ||||
| T4108 | 3-TYP | 120241-79-4 | 98% |
|
| 3-TYP is a selective SIRT3 inhibitor. | ||||
| T16932 | SRT 2183 | 1001908-89-9 | 98% |
|
| SRT 2183 is a selective activator of Sirtuin-1 (SIRT1, EC1.5 : 0.36 μM). | ||||
| T1818 | Tenovin-6 | 1011557-82-6 | 98% |
|
| Tenovin-6 is a p53 transcriptional activity agonist. | ||||
