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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TQ0142 | 10-Oxo Docetaxel | Docetaxel Impurity 1 | Others |
10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties. | |||
T19163 | 7-Epi-10-oxo-docetaxel | Docetaxel Impurity 2 | Others |
7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC. | |||
TQ0247 | 7-Epi-docetaxel | 7-Epidocetaxel,4-epi-Docetaxel,7-Epitaxotere | Others |
7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel. | |||
T38644 | Docetaxal | PNU-101383,10-Acetyl docetaxel | |
Docetaxal, also known as 10-Acetyl docetaxel, is an analog of Docetaxel exhibiting potent anticancer properties. It acts as a microtubule disassembly inhibitor, effectively inhibiting mitosis. | |||
T74418 | Sudocetaxel | ||
Sudocetaxel is a compound that serves as a microtubule depolymerization inhibitor, specifically designed for the pH-sensitive delivery of docetaxel. | |||
T11122 | DUPA(OtBu)-OH | Others | |
DUPA(OtBu)-OH is a DUPA precursor. DUPA is used as the targeting moiety to actively deliver Docetaxel (DTX) for treatment of Prostate-Specific Membrane Antigen (PSMA) expressing prostate cancer. PSMA has a high affinity ... | |||
T15713 | Larotaxel | XRP9881 | P-gp |
Larotaxel (XRP9881) is a taxane analogue that has anticancer activity, exerts its cytotoxic effects by promoting tubulin assembly and stabilizing microtubules, and ultimately induces cell death through apoptosis. Larotax... | |||
T60372 | ALDH3A1-IN-1 | ||
ALDH3A1-IN-1 (Compound 18) is a potent ALDH3A1 inhibitor with an IC 50 of 1.61 μM. ALDH3A1-IN-1 is more potent than DEAB against patient-derived primary prostate tumor epithelial cells, as single agents or in combination... | |||
T6695 | Tasquinimod | ABR-215050 | HDAC |
Tasquinimod (ABR-215050) is a quinoline-3-carboxamide linomide analog with antiangiogenic and potential antineoplastic activities. Tasquinimod has been shown to decrease blood vessel density but the exact mechanism of ac... | |||
TP2051 | CTCE-9908 | CTCE 9908 | |
CXCR4 antagonist; induces mitotic catastrophe in ovarian cancer cells. Displays additive cytotoxic effects when given with taxol. Enhances the efficacy of docetaxel in a mouse model. | |||
T15514 | Hydroxy-PEG10-Boc | Others | |
Hydroxy-PEG10-Boc is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Hydroxy-PEG10-Boc can be conjugated to Paclitaxel or docetaxel [2]. | |||
T28216 | NTRC 0066-0 | NTRC-0066-0,NTRC-00660,NTRC00660,NTRC0066-0 | |
NTRC-0066-0 is a a highly potent and selective inhibitor of TTK. NTRC 0066-0 inhibits the phosphorylation of a TTK substrate and induces chromosome missegregation. NTRC 0066-0 inhibits tumor growth in MDA-MB-231 xenograf... | |||
T82327 | GEM–IB | ||
Gemcitabine-ibandronate (GEM–IB), a conjugate of gemcitabine (GEM)-5'-phosphate with ibandronate (IB), exhibits efficacy both as a monotherapy and synergistically with Docetaxel (DTX), resulting in diminished tumor burde... |
カタログ番号 | 製品名 | 別名 | ターゲット |
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T1034 | Docetaxel | NSC 628503,RP-56976 | Apoptosis , Microtubule Associated , Endogenous Metabolite |
Docetaxel (RP-56976) is a semi-synthetic analog of paclitaxel, a microtubule depolymerization inhibitor (IC50=0.2 μM). Docetaxel attenuates the effects of bcl-2 and bcl-xL gene expression and exhibits apoptosis-inducing,... | |||
T0186 | Docetaxel trihydrate | RP-56976 (Trihydrate),RP56976 (NSC 628503) Trihydrate | Apoptosis , BCL , Microtubule Associated |
T2543 | Cabazitaxel | XRP6258,RPR-116258A,TXD 258,taxoid XRP6258 | Microtubule Associated , Autophagy |
Cabazitaxel (taxoid XRP6258) is a taxane and antineoplastic agent which is currently used in the therapy of castration-resistant metastatic prostate cancer after failure of docetaxel. |