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T22767 |
ER 50891
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Retinoid Receptor
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ER-50891 is a potent retinoic acid receptor alpha (RARα) antagonist. er-50891 reduces the inhibitory effect of allosteric retinoic acid and restores osteoblast differentiation induced by bone morphogenetic protein 2. |
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T38894 |
IHVR-17028
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Influenza Virus
,
Glucosidase
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IHVR-17028 is a potent broad-spectrum ERα-glucosidase I (α-glucosidase? I) inhibitor with IC50 of 0.24 μM and antiviral activity. IHVR-17028 inhibited BVDV, TCRV and DENV, and EC50 values were 0.4 μM, 0.26 μM and 0.3 μM,... |
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T70031 |
ER-38925
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Others
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ER-38925 is a retinoic acid receptor (rar) subtype α-selective agonist |
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T13700 |
GDC-0927 Racemate
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SRN-927 Racemate |
Others
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GDC-0927 Racemate is a degrader of estrogen receptor, is used in the research of ER-related diseases, potently inhibits ER-α activity, with an IC50 of 0.2 nM. |
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T40166 |
Bexirestrant
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Others
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Bexirestrant is an orally active ER-α degrader commonly employed in the research of antiestrogen and antineoplastic therapies. |
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T15554 |
IHVR-19029
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Others
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IHVR-19029 is an effective endoplasmic reticulum (ER) α-glucosidases I and II inhibitor (IC50: 0.48 μM for ER a-glucosidase I). IHVR-19029 efficiently blocks the replication of several hemorrhagic fever viruses, such as ... |
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T27590 |
IHVR-11029
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IHVR 11029 |
Others
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IHVR-11029 is a potent inhibitor of ER α-glucosidase. IHVR-11029 is active against multiple hemorrhagic fever viruses and efficiently disrupts the morphogenesis of a broad spectrum of enveloped viruses. |
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T79382 |
ER degrader 6
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Estrogen Receptor/ERR
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ER degrader 6 (compound 35s) is a potent selective estrogen receptor modulator (SERM) with the capacity to degrade Estrogen Receptor (ER)α. It disrupts the microtubule network, inhibiting tubulin polymerization, and effe... |
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T78102 |
ER 50891 quarterhydrate
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Others
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ER 50891 quarterhydrate is a potent RARα (retinoic acid receptor α) antagonist that markedly diminishes the inhibitory effects of ATRA (all-trans retinoic acid) on osteoblastogenesis induced by BMP 2 (bone morphogenetic ... |
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T62793 |
EB-0150
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Others
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EB-0150 is a potent inhibitor of ER α-glucosidase (α-Glu) I (IC50s: 0.73 μM) and (α-Glu) II (IC50s: 0.0337 μM). EB-0150 is an N-substituted valerian derivative with broad-spectrum antiviral effects. EB-0150 has potential... |
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T63303 |
EB-0176
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Others
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EB-0176 is an N-substituted valerian derivative that exhibits broad-spectrum antiviral activity and is a potent ER α-glucosidase (α-Glu) I and II inhibitor with IC50s of 0.6439 and 0.0011 μM, respectively.EB-0176 exhibit... |
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T27050 |
CM-10-18
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CM-1018 |
Others
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CM-10-18 is a potent inhibitor of ER α-glucosidase. CM-10-18 demonstrated superior in vitro antiviral activity against representative viruses from four viral families causing hemorrhagic fever. CM-10-18 efficiently prote... |
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T18697 |
SNIPER(ER)-87
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Others
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SNIPER(ER)-87 is a chemical compound composed of a derivative of the inhibitor of apoptosis protein (IAP) ligand LCL161 conjugated to the estrogen receptor α (ERα) ligand 4-hydroxytamoxifen using a PEG linker. It effecti... |
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T61923 |
ERRα antagonist-2
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Others
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ERRα antagonist-2 (Compound 11) is a potential Reverse agonist of ERR α (estrogen receptor related receptor α) (IC50=0.80 μ M). ERRα antagonist-2 can inhibit the migration and invasion of ER-negative MDA-MB-231 cells. ER... |
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T63170 |
EB-0156
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Others
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EB-0156 is a potent inhibitor of ER α-glucosidase (α-Glu) I and II with IC50 values of 0.0479 and <0.001 μM, respectively. EB-0156 is an N-substituted valerian derivative with broad-spectrum antiviral activity. EB-0156 h... |
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T62818 |
LSD1/ER-IN-1
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Others
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LSD1/ER-IN-1 (compound 11g) is a potent inhibitor of ER and LSD1 that acts on LSD1 (IC50: 1.55 μM). LSD1/ER-IN-1 showed good anti-proliferative effect on MCF-7 breast cancer cells (IC50: 8.79 μM). |
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T28275 |
OUP-186
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OUP186 |
Others
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OUP-186 is a high affinity and human/rat species-selective antagonist of histamine H3 receptor. OUP-186 suppressed the proliferation of breast cancer cells. The IC50 values at 48 hours for OUP-186 was approximately 50 μM... |
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T61690 |
MEH-IN-1
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Others
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mEH-IN-1 (Compound 62) is a potent inhibitor of microsomal epoxide hydrolase (mEH), with an IC50 value of 2.2 nM. mEH is an α/β-fold hydrolase enzyme that is widely expressed in various mammalian tissues, responsible for... |
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T35676 |
17β-hydroxy Exemestane
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Others
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17β-hydroxy Exemestane is the primary active metabolite of exemestane . It is formed by metabolism of exemestane by the cytochrome P450 (CYP) isoforms CYP1A and CYP4A11. 17β-hydroxy Exemestane is an aromatase inhibitor (... |
