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Cell Counting Kit-8 (CCK-8)
Inhibitor Cocktails
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| Cat. No. | 製品名 | CAS No. | Purity | Chemical Structure |
|---|---|---|---|---|
| T5854 | AM580 | 102121-60-8 | 98% |
|
| AM580 is a retinoic acid receptor agonist that is selective for RARα( IC50 : 8 nM ) | ||||
| T6696 | Tazarotene | 118292-40-3 | 98% |
|
| Tazarotene is a synthetic, topical retinoid. Tazarotene induces the expression of tazarotene-induced gene 3 (TIG3), a tumor suppressor gene. In psoriasis, tazaro... | ||||
| T1002 | Etodolac | 41340-25-4 | 98% |
|
| Etodolac inhibits the activity of cyclooxygenase I and II, thereby preventing the formation of prostaglandin which is involved in the induction of pain, fever, a... | ||||
| T1330 | Acitretin | 55079-83-9 | 98% |
|
| Acitretin is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. | ||||
| T7586 | Trifarotene | 895542-09-3 | 98% |
|
| trifarotene is a potent and selective RARγ agonist with 65-fold and 16-fold selectivitiy for the RARγ (EC50=7.7 nM) over RARα (EC50=500 nM) and RARβ (EC50=125 nM... | ||||
| T0499 | Oxybenzone | 131-57-7 | 98% |
|
| Oxybenzone is an organic compound used in sunscreens. It is a derivative of benzophenone. | ||||
| T10261 | AGN 196996 | 958295-17-5 | 98% |
|
| AGN 196996 is a potent and selective inhibitor of RARα (Ki: 2 nM).AGN 196996 has very low affinity for RARβ and RARγ, with a Ki of 1087 nM and 8523 nM, respectiv... | ||||
| T5843 | Tarenflurbil | 51543-40-9 | 98% |
|
| R-flurbiprofen is the non-cyclooxygenase inhibiting R-enantiomer of the non-steroidal anti-inflammatory drug flurbiprofen, which was assessed as a remedy for Alz... | ||||
| T3000 | Magnolol | 528-43-8 | 98% |
|
| Magnolol is a dual agonist of RXRα( EC50=10.4 μM) and PPARγ(EC50=17.7 μM). It blocks TNF-α-induced NF-KB activation. | ||||
| T16425 | PA452 | 457657-34-0 | 98% |
|
| PA452 is a selective antagonist of retinoic X receptor (RXR) and suppresses the effect of Retinoic acid on Th1/Th2 development. | ||||
| T1051 | Retinoic acid | 302-79-4 | 98% |
|
| Tretinoin binds to and activates retinoic acid receptors (RARs), thereby inducing changes in gene expression that lead to cell differentiation, decreased cell pr... | ||||
| T22192 | BMS 195614 | 253310-42-8 | 98% |
|
| BMS 195614 is a selective RARα antagonist. BMS 195614 can bind to the RARα subunit. | ||||
| T7370 | Talarozole | 201410-53-9 | 98% |
|
| Talarozole is an oral systemic all-trans retinoic acid metabolism blocking agent (RAMBA). Talarozole inhibits both CYP26A1 and CYP26B1 with IC50s of 5.4 and 0.46... | ||||
| T4538 | Palovarotene | 410528-02-8 | 98% |
|
| Palovarotene is an agonist of nuclear retinoic acid receptor γ (RAR-γ). | ||||
| T6410 | Bexarotene | 153559-49-0 | 98% |
|
| Bexarotene is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL). | ||||
| T6694 | Tamibarotene | 94497-51-5 | 98% |
|
| Tamibarotene is an orally active, synthetic retinoid, developed to overcome all-trans retinoic acid (ATRA) resistance, with potential antineoplastic activity. | ||||
| T22920 | LE135 | 155877-83-1 | 98% |
|
| LE135 is a potent RAR antagonist that binds selectively to RARα (Ki of 1.4 μM) and RARβ (Ki of 220 nM), and has a higher affinity to RARβ. LE135 is highly select... | ||||
| T22049 | BMS 753 | 215307-86-1 | 98% |
|
| BMS 753 is an agonist of isotype-selective retinoic acid receptor α (RARα, Ki= 2 nM). | ||||
| T14089 | AC-261066 | 870773-76-5 | 98% |
|
| AC-261066 is an orally available and isoform-selective agonist of RARβ2 with a pEC50 of 8.0. | ||||
| T15811 | LY2955303 | 1433497-19-8 | 98% |
|
| LY2955303 is an effective and selective antagonist of retinoic acid receptor gamma (RARγ, Ki = 1.09 nM). | ||||
