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T9163 |
IRONE
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Others
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Irone is used as a fragrance ingredient. |
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T24885L |
Tiaspirone hydrochloride
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BMY-13859 hydrochloride,Tiaspirone hydrochloride（87691-91-6 Free base) |
Dopamine Receptor
,
5-HT Receptor
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Tiaspirone hydrochloride (BMY-13859 hydrochloride) exhibits antipsychotic activity. Tiaspirone hydrochloride influences the electrophysiological activity of dopaminergic neurons in the substantia nigra zona compacta (A9 ... |
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T4576 |
Perospirone
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Lullan |
Dopamine Receptor
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5-HT Receptor
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Perospirone (Lullan) is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist. |
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T24885 |
Tiospirone
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BMY 13859-1 |
Dopamine Receptor
,
5-HT Receptor
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Tiospirone (BMY 13859-1 free base) is a 5-HT2 receptor antagonist and dopamine blocker that inhibits D2, 5-HT1a, 5-HT7, and sigma receptors.Tiospirone is used in the study of neurological disorders such as schizophrenia. |
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T19917 |
Gepirone
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5-HT Receptor
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Gepirone is a 5-HT1A receptor agonist belonging to the buspirone family. Gepirone HCl possesses greater selectivity for the 5-HT1A receptor than SSRIs. |
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T3179 |
Eptapirone
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F 11440 |
5-HT Receptor
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Eptapirone (F 11440) is a highly effective and selective 5-HT1A receptor agonist with marked antidepressant and anxiolytic potential. |
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T7412 |
Tandospirone citrate
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SM-3997 citrate |
5-HT Receptor
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Tandospirone citrate (SM-3997 citrate) is a potent and selective 5-HT1A receptor partial agonist (Ki : 27 nM) |
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T21011 |
Buspirone
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Buspirone free base,Ansial |
5-HT Receptor
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Buspirone (Buspirone free base) is an azaspiro compound which has a role as an anxiolytic drug, a sedative, a serotonergic agonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. |
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T8136 |
Perospirone hydrochloride
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Perospirone HCl,SM-9018 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
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Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist. |
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T2132 |
Buspirone hydrochloride
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Buspirone HCl,Narol,Buspar |
Dopamine Receptor
,
5-HT Receptor
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Buspirone hydrochloride (Buspar) is a 5HT(1A) receptor agonist, used to treat generalized anxiety disorder (GAD). |
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T71138L |
Binospirone
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MDL 73005EF |
5-HT Receptor
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Binospirone (MDL 73005EF) is a 5-HT1A receptor agonist with anxiolytic activity used in the study of glaucoma and movement disorders associated with neurologic dysfunction. |
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T68172 |
Zalospirone
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5-HT Receptor
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Zalospirone is a 5-HT1A receptor agonist that can be used to study anxiety disorders and major depressive disorder. |
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T22871 |
Ipsapirone
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5-HT Receptor
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Ipsapirone is a partial agonist of 5-HT1A receptor and produces an inhibitory effect on 5-HT2 and the α1-adrenergic function at high doses. |
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T83909 |
6-hydroxy Buspirone
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BMY 28674,BMS-52821 |
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6-Hydroxy Buspirone, an active metabolite of the anxiolytic compound buspirone, is produced via the cytochrome P450 (CYP) isoform CYP3A4. This compound exhibits affinity for the serotonin (5-HT) receptor subtype 5-HT1A, ... |
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T27623 |
Ipsapirone hydrochloride
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BAY q 7821,BAY q-7821,BAY q7821,Ipsapirone HCl |
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Ipsapirone, a pyrimidinylpiperazine ligand, is potent and specific for 5-HT1A receptors and has potential therapeutic use in affective disorders. |
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T70183 |
Eptapirone fumarate
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Eptapirone, also known as F11440, is a potent 5HT(1A) receptor agonist with marked anxiolytic and antidepressant potential. The affinity of F 11440 for 5-HT1A binding sites (pKi, 8.33) was higher than that of buspirone (... |
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T71138 |
Binospirone mesylate
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Binospirone mesylate is a putative 5-HT(1A) receptor antagonist. |
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T62215 |
Tandospirone hydrochloride
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Tandospirone (SM-3997) hydrochloride is a potent, selective 5-HT1A receptor partial agonist (Ki: 27 nM) that exhibits anxiolytic and antidepressant activity. tandospirone hydrochloride can be used to study central nervou... |
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T32868 |
Lophirone A
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Lophirone A is a biflavonoid-related polyphenol. |
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TQ0315 |
Tandospirone
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SM-3997 |
5-HT Receptor
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Tandospirone (SM-3997) is a selective partial agonist of 5-HT1A receptor (Ki: 27 nM) that displays selectivity over SR-2, SR-1C, α1, α2, D1 and D2 receptors (Kis: 1300-41000 nM). |
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T69038 |
Teroxirone
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Teroxirone, also known as Triglycidyl Isocyanurate and Tris(2,3-epoxypropyl) Isocyanurate, is a triazene triepoxide with antineoplastic activity. Teroxine alkylates and cross-links DNA, thereby inhibiting DNA replicatio... |
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T16543 |
Pironetin
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Microtubule Associated
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Pironetin binds to α-tubulin and is an effective inhibitor of microtubule polymerization. It also has cell cycle arrest and antitumor activity. Pironetin is an α/β unsaturated lactone isolated from Streptomyces species. |
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T70814 |
Alnespirone
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Alnespirone, also known as S-20499, is a selective 5-HT1A receptor full agonist of the azapirone chemical class. It has both antidepressant and anxiolytic effects. |
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T69034 |
Enilospirone
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Enilospirone is a selective 5-HT1A receptor agonist of the azapirone class. |
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T68715 |
Anaxirone
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Anaxirone is a synthetic triepoxide alkylating agent with potential antineoplastic activity. Anaxirone alkylates DNA via actual or derived epoxide groups, resulting in inhibition of DNA synthesis. This agent has been sho... |
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T26709 |
Azadirone
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Azadirone is a limonoid tetranortriterpene. Azadirone can sensitize cancer cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) through ROS-ERK-CHOP-mediated up-regulation of DR4 and DR5 signaling, do... |
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T24923 |
Umespirone
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Umespirona,Umespironum |
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Umespirone is a potential antipsychotic/anxiolytic drug of the azapirone class. It possesses anxiolytic and antipsychotic properties. |
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T70666 |
Alnespirone hydrochloride
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Alnespirone hydrochloride is a selective 5-HT1A receptor full agonist of the azapirone chemical class. It has both antidepressant and anxiolytic effects. |
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TMIH-0427 |
Perospirone hydrochloride-d8
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Perospirone hydrochloride-d8 is a deuterated compound of Perospirone hydrochloride. Perospirone hydrochloride has a CAS number of 129273-38-7. Perospirone hydrochloride is an atypical antipsychotic agent for the treatmen... |
