|
T69868 |
ZIKV-IN-K22
|
|
Others
|
|
ZIKV-IN-K22 is a potent antiviral agent against a broad range of coronaviruses by targeting membrane-bound viral RNA replication, effectively inhibiting ZIKV with IC50 of 2.1 μM. |
|
T69867 |
BN80933
|
|
Others
|
|
BN80933 is a dual inhibitor of lipid peroxidation and neuronal nitric oxide synthase; Neuroprotectant. |
|
T4531 |
GSK2200150A
|
|
Antibacterial
|
|
GSK2200150A is an anti-tuberculosis (TB) agent identified by high-throughput screening (HTS) campaign. |
|
T6850L |
GSK2292767 FA
|
GSK2292767 FA(1254036-66-2 Free base) |
PI3K
|
|
GSK2292767 FA is a potent and selective inhibitor of PI3Kδ (pIC50 : 10.1).GSK2292767 FA is more than 500-fold more selective than other PI3K isoforms.GSK2292767 FA can be used in the study of respiratory diseases. |
|
T11481 |
GSK2239633A
|
|
CCR
|
|
|
|
T2281 |
GSK2256098
|
GSK 2256098,GSK-2256098,GTPL7939 |
Apoptosis
,
FAK
|
|
GSK2256098 (GTPL7939) is a small molecule FAK kinase inhibitor. |
|
T15430 |
GSK2256294A
|
GSK 2256294 |
Others
,
Epoxide Hydrolase
|
|
GSK2256294A (GSK 2256294) is potent, selective inhibitor of recombinant human, rat and mouse sEH with IC50 of 27 pM, 61 pM and 189 pM, respectively. |
|
T6850 |
GSK2292767
|
|
PI3K
|
|
GSK2292767 is a potent and selective PI3Kδ inhibitor. |
|
T25469 |
GSK223
|
GSK 223,GSK-223 |
Others
|
|
GSK223 is an iE-DAP-stimulated IL-8 release inhibitor via the NOD1 signaling pathway. |
|
T11482 |
GSK2245035
|
|
Others
|
|
GSK2245035 is a highly selective intranasal TLR7 agonist with preferential Type-1 interferon (IFN)-stimulating properties (pEC50s: 9.3 and 6.5 for IFNα and TFNα). It effectively suppresses allergen-induced Th2 cytokine p... |
|
T27459 |
GSK2263167
|
GSK-2263167,GSK 2263167 |
Others
|
|
GSK2263167 is an agonist of S1P1 receptor. |
|
T74660 |
M4K2234
|
|
Others
|
|
M4K2234 (compound 26b), an ALK2 inhibitor, demonstrates selective inhibition of ALK2 and ALK5 with IC50 values of 5 nM and 2144 nM, respectively. Serving as a chemical probe for ALK1 and ALK2 protein kinases, M4K2234 hol... |
|
T27457 |
GSK2210875
|
GSK-2210875,GSK 2210875 |
Others
|
|
GSK2210875 is a mGluR5 antagonist with oral activity. |
|
T69830 |
GSK2239633
|
|
Others
|
|
GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2... |
