18
1
4
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T38707 | MPC-0767 | ||
MPC-0767, a potent, selective, and orally active hsp90 inhibitor, is the L-alanine ester prodrug of MPC-3100, exhibiting enhanced chemical stability. | |||
T13298 | Verubulin hydrochloride | MPC-6827 hydrochloride | Microtubule Associated |
Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxic activities,with potent anticancer activity in human MX-1 brea... | |||
T21600 | MPC-3100 | ||
MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of Hsp90 with significant antitumor activity [1]. | |||
T17229 | Verubulin | MPC 6827 | Microtubule Associated |
Verubulin is a microtubule-disrupting agent with potent and broad-spectrum in vitro and in vivo cytotoxic activities. | |||
T5376 | Aranidipine | MPC1304 | Calcium Channel |
Aranidipine (MPC1304) (MPC1304) is a calcium channel antagonist with potent and long-lasting antihypertensive effects. | |||
T5843 | Tarenflurbil | MPC7869,(R)-Flurbiprofen,R-flurbiprofen | Retinoid Receptor , Autophagy |
Tarenflurbil ((R)-Flurbiprofen) is the non-cyclooxygenase inhibiting R-enantiomer of the non-steroidal anti-inflammatory drug flurbiprofen, which was assessed as a remedy for Alzheimer's disease. | |||
T1768 | 7ACC2 | Mitochondrial Metabolism , Monocarboxylate transporter | |
7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells. | |||
T2607 | MSDC 0160 | CAY10415,Mitoglitazone,MSDC0160,MSDC-0160 | Others , IGF-1R , Mitochondrial Metabolism |
MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease. | |||
T9235 | GW604714X | 2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]- | Mitochondrial Metabolism |
GW604714X (2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-) were found to be potent inhibitors of mitochondrial respiration supported by pyruvate | |||
T71538 | AMPCP | ||
AMPCP is an Ecto-5'-nucleotidase (CD73) inhibitor. | |||
T74285 | EDMPC | ||
EDMPC, a cationic lipid, exhibits an enhanced capability for DNA delivery to pulmonary tissues. It facilitates intralobar DNA transfer in rodents [1]. | |||
T79693 | PIMPC | GSK-3 | |
PIMPC, a compound endowed with antioxidant and metal-chelating properties, acts as a novel inhibitor of glycogen synthase kinase 3 (GSK-3), and exhibits potential therapeutic effects for Alzheimer's disease [1]. | |||
T39792 | AMPC | ||
AMPC, a powerful and efficient inhibitor of TFF3, demonstrates inhibitory effects on cell proliferation, survival, oncogenicity, and CSC-like behavior in TFF3-positive CMS4 CRC cells. It acts as a promising standalone an... | |||
T60419 | Cyclic HPMPC | ||
Cyclic HPMPC is a potent antiviral agent that enhances arterial oxygen saturation in mice infected with the lethal vaccinia virus (IHD strain) and alleviates congenital guinea pig cytomegalovirus (GPCMV) infection outcom... | |||
T24495 | MPCI | ||
MPCI is a selective melanocortin-4 receptor antagonist. | |||
T4441 | UK-5099 | UK 5099,PF-1005023,UK5099 | Others , Mitochondrial Metabolism |
UK-5099 (PF-1005023) is a specific and potent inhibitor of MPC carrier activity [1]. It potently inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria (IC50: 50 nM) [1]. | |||
T38715 | MSDC-0602K | MSDC-0602K,Azemiglitazone potassium | PPAR |
MSDC-0602K (Azemiglitazone potassium) (Azemiglitazone potassium) is a PPARγ-sparing thiazolidinedione (Ps-TZD) compound that binds to PPARγ with an IC50 of 18.25 μM. It also modulates the mitochondrial pyruvate carrier (... | |||
T4639 | Azemiglitazone | MSDC 0602 | Mitochondrial Metabolism , mTOR |
Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T5782 | Bevirimat | YK FH312,MPC-4326,PA-457 | HIV Protease |
Bevirimat (PA-457) is a first-in-class inhibitor of HIV-1 maturation, blocking the cleavage of the Gag capsid (CA) precursor, CA-SPI, to mature CA protein during virion maturation. |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPH-00695 | OmpC Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Forms pores that allow passive diffusion of small molecules across the outer membrane.; (Microbial infection) Supports colicin E5 entry in the absence of its major receptor OmpF.; (Microbial infection) A mixed OmpC-OmpF ... | |||
TMPH-00696 | OmpC Protein, E. coli, Recombinant | E. coli | E. coli |
Forms pores that allow passive diffusion of small molecules across the outer membrane.; (Microbial infection) Supports colicin E5 entry in the absence of its major receptor OmpF.; (Microbial infection) A mixed OmpC-OmpF ... | |||
TMPH-02376 | OmpC Protein, Klebsiella pneumoniae, Recombinant (His & Myc) | Klebsiella pneumoniae | E. coli |
Forms pores that allow passive diffusion of small molecules across the outer membrane. In K.pneumoniae it has been shown to bind the C1Q component and activate the classical pathway of the complement system. OmpC Protein... | |||
TMPH-00676 | OmpC Protein, E. coli O157:H7, Recombinant (His & Myc & SUMO) | E. coli | E. coli |
Forms pores that allow passive diffusion of small molecules across the outer membrane. |