|
T9926 |
Omalizumab
|
|
Others
|
|
Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE) |
|
T9901A-006 |
Vonlerolizumab
|
Pogalizumab,RG 7888,MOXR 0916 |
Others
|
|
Vonlerolizumab(MOXR 0916) is a humanized IgG agonistic OX40-specific monoclonal antibody with potential antitumor activity for the study of tumors and immune diseases. |
|
T9962 |
Mepolizumab
|
SB 240563 |
IL Receptor
|
|
Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5. Mepolizumab can be used in studies about severe eosinophilic asthma and eosinophilic granulomatosis with polyangiitis. |
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T9902 |
Atezolizumab
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|
Apoptosis
,
PD-1/PD-L1
,
Autophagy
|
|
Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1 but not the interaction of PD-L2 with PD-1. |
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T9914 |
Vedolizumab
|
|
Integrin
|
|
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis. |
|
T77426 |
Pascolizumab
|
SB-240683 |
IL Receptor
|
|
Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis. |
|
T76781 |
Itolizumab
|
EQ-001 |
Others
|
|
Itolizumab (Anti-Human CD6 Recombinant Antibody) is a recombinant anti-CD6 monoclonal antibody that humanizes the extracellular SRCR distal domain 1 of CD6. Itolizumab slows T cell proliferation and inhibits the producti... |
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T76724 |
Nemolizumab
|
CIM331 |
Interleukin
|
|
Nemolizumab (CIM331) is a humanized monoclonal antibody against human interleukin-31 receptor A that inhibits the binding and subsequent signal transduction of interleukin-31 (IL-31) to its receptor. Nemolizumab can be u... |
|
T9908 |
Pembrolizumab
|
|
PD-1/PD-L1
|
|
Pembrolizumab is a humanized monoclonal antibody inhibiting the PD-1 receptor and the first in the class of agents called the HER2 dimerization inhibitors that impairs the ability of HER2 to bind to other members of the ... |
|
T76909 |
Apolizumab
|
|
|
|
Apolizumab (Hu1D10), a humanized monoclonal antibody targeting the Human leukocyte antigen-DR beta-chain, has been shown to induce apoptosis in chronic lymphocytic leukemia (CLL) cells in vitro [1] [2]. |
|
T76808 |
Fontolizumab
|
|
|
|
Fontolizumab (HuZAF) is a humanized monoclonal antibody targeting IFN-gamma, functioning as an immunosuppressive agent. It is utilized in the study of Crohn’s disease [1]. |
|
T77154 |
Etrolizumab
|
|
|
|
Etrolizumab (rhuMAb Beta7), a gut-selective anti-β7 integrin monoclonal antibody, targets the β7 subunit of α4β7 and αEβ7 integrins specifically, demonstrating affinity with K i values of 18 nM for Human α4β7 and 1800 pM... |
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T76963 |
Certolizumab pegol
|
|
|
|
Certolizumab pegol (Certolizumab) is a recombinant, humanized monoclonal antibody fragment that has been modified with polyethylene glycol (PEG), which selectively targets and neutralizes tumor necrosis factor-alpha (TNF... |
|
T77061 |
Letolizumab
|
|
|
|
Letolizumab (BMS-986004), a monoclonal antibody directed at CD40L, is engineered to express a mutant IgG1 devoid of effector functions, such as Fc binding and complement fixation. It effectively reduces rejection and thr... |
|
T82611 |
Dapirolizumab pegol
|
CDP 7657 |
|
|
Dapirolizumab pegol (CDP 7657), a monoclonal antibody of the Fab'-IgG-κ class, targets CD40LG/TNFSF5 and is conjugated with a pegol moiety. The antibody was initially cloned from the Norway rat (Rattus norvegicus). |
