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T11847L |
Liarozole
|
R75251 dihydrochloride |
P450
,
Retinoid Receptor
|
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Liarozole (R75251 dihydrochloride) is a cytochrome P450 (CYP450) dependent inhibitor, orally active, it also a potent inhibitor of estrogen (via inhibition of aromatase) and testicular androgen synthesis (inhibition of 1... |
|
T20419 |
Raloxifene
|
Pharoxifene,Raloxifenum,Keoxifene,LY-139481 |
Estrogen Receptor/ERR
,
Others
|
|
Raloxifene (LY-139481) is a selective oestrogen receptor modulator. It has effects on bone and breast cancer and cardiovascular disease risk. |
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T11098 |
Droloxifene
|
3-Hydroxytamoxifen |
Estrogen Receptor/ERR
|
|
Droloxifene (3-Hydroxytamoxifen), a tamoxifen derivative, is an oral active and selective estrogen receptor modulator.Droloxifene induced p53 expression and apoptosis in McF-7 cells.Fluroxifene has anti-estrogen and anti... |
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T31124 |
CW 008
|
CW-008,CW008 |
|
|
CW 008 is an activator of the cAMP/PKA/CREB pathway. It promotes osteogenic differentiation of human bone marrow derived mesenchymal stem cells in vitro and increases bone mass and bone volume density in ovariectomized m... |
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T40245 |
Miroestrol
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|
|
|
Miroestrol is a potent phytoestrogen compound with multifaceted biological effects. It induces a mammogenic effect and demonstrates neuroprotective properties, along with the ability to prevent bone loss in ovariectomize... |
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T35676 |
17β-hydroxy Exemestane
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|
|
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17β-hydroxy Exemestane is the primary active metabolite of exemestane . It is formed by metabolism of exemestane by the cytochrome P450 (CYP) isoforms CYP1A and CYP4A11. 17β-hydroxy Exemestane is an aromatase inhibitor (... |
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T83766 |
Moexiprilat
|
RS 10029 |
|
|
Moexiprilat, an active metabolite of the prodrug moexipril formed through side chain ester hydrolysis in vivo, functions as an angiotensin-converting enzyme (ACE; IC50 = 2.1 nM) inhibitor. At a concentration of 10 nM, it... |
