|
T1264 |
Ciprofibrate
|
Win35833 |
PPAR
|
|
Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity. |
|
T70289 |
Terpendole E
|
|
|
|
Terpendole E is an atypical L5 site inhibitor. |
|
T10900 |
CUDA
|
|
PPAR
,
Epoxide Hydrolase
|
|
CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases the activity of peroxisome proliferator-activated receptor (PPAR... |
|
T10505 |
PPARα-MO-1
|
|
PPAR
|
|
PPARα-MO-1 is a potent modulator of PPARα. |
|
T1415 |
Gemfibrozil
|
CI-719,Jezil,Decrelip,Lopid |
P450
,
Adrenergic Receptor
,
PPAR
|
|
Gemfibrozil (CI-719) interacts with peroxisome proliferator-activated receptors (PPARalpha) resulting in PPARalpha-mediated stimulation of fatty acid oxidation and an increase in lipoprotein lipase (LPL) synthesis. Gemfi... |
|
T5532 |
BMS-687453
|
|
PPAR
|
|
BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays. |
|
T25198 |
C-333H
|
C333H |
|
|
C-333H is a new PPARalpha/gamma dual agonist. |
|
T70141 |
MDK80908
|
|
|
|
MDK80908, also known as PPARalpha/gamma agonist N15, is a dual PPARα/γ agonist, ameliorating insulin resistance and gluconeogenesis in vivo and vitro. MDK80908 has CAS#1821380-90-8. |
|
T70290 |
YUN90389
|
|
|
|
YUN90389, also known as PPARalpha/delta-IN-11, is a the first reported pparα/δ dual antagonist. YUN90389 was first reported in Bioorganic & Medicinal Chemistry Letters (2019), 29(3), 503-508. YUN90389 has CAS#1673590-38-... |
