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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T1994 | Pictilisib | RG7321,GDC-0941 | Apoptosis , PI3K , Autophagy |
Pictilisib (GDC-0941) (GDC-0941) is a potent pan inhibitor of class I catalytic subunits of PI3K (IC50s: 3/33/3/75 nM for p110α/β/δ/γ). | |||
T11381 | Pictilisib dimethanesulfonate | GDC-0941 dimethanesulfonate,GDC-0941 2 MeSO3H salt | Apoptosis , DNA-PK , PI3K , mTOR , Autophagy |
Pictilisib dimethanesulfonate (GDC-0941 2 MeSO3H salt) is a potent inhibitor of PI3Kα/δ with IC50 of 3 nM, with modest selectivity against p110β (11-fold) and p110γ (25-fold). |