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Search Results for " S-adenosyl "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T79919	S-Adenosyl-L-methionine (1,4-butanedisulfonate)	Ademetionine (1,4-butanedisulfonate),S-Adenosyl methionine (1,4-butanedisulfonate),AdoMet (1,4-butanedisulfonate)	Endogenous Metabolite
	S-Adenosyl-L-methionine (SAMe) 1,4-butanedisulfonate functions as an orally active methyl group donor and serves as a dietary supplement known for its significant antidepressant properties. Additionally, it plays anti-pr...		Endogenous Metabolite
T7305	JQEZ5		Histone Methyltransferase
	JQEZ5 is an inhibitor of EZH2 lysine methyltransferase (IC50 = 11.1 nM).		Histone Methyltransferase
T124334	S-Adenosyl-L-methionine tosylate
	S-Adenosyl-L-methionine tosylate is a useful organic compound for research related to life sciences and the catalog number is T124334.
T124985	S-Adenosyl-L-Methionine iodide salt
	S-Adenosyl-L-Methionine iodide salt is a useful organic compound for research related to life sciences and the catalog number is T124985.
T67753	Trifluoromethyl-tubercidin		Influenza Virus
	Trifluoromethyl-tubercidin (TFMT) inhibits host MTr1 and suppresses virus replication. TFMT inhibits MTr1 through interaction at its S-adenosyl-l-methionine binding pocket to restrict influenza virus replication. TFMT wa...		Influenza Virus
T9626	Cycloleucine		NMDAR
	Cycloleucine is an antagonist of NMDA receptor associated glycine receptor with a Ki of 600 μM. Cycloleucine is also a competitive inhibitor of S-adenosyl-methionine mediated methylation with anxiolytic and cytostatic ef...		NMDAR
T6360	3-deazaneplanocin A HCl		Others , Histone Methyltransferase
	3-deazaneplanocin A (DZNeP)HCl, an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM.		Others , Histone Methyltransferase
T35617	Mitoguazone	MGBG,Methyl-GAG	Apoptosis , HIV Protease
	Mitoguazone (Methyl-GAG) is a selective S-adenosyl-methionine decarboxylase inhibitor that penetrates the blood-brain barrier and disrupts polyamine biosynthesis. Mitoguazone is a synthetic polycarbonyl derivative with a...		Apoptosis , HIV Protease
T25385	Eritadenine	Lentysine,D-Eritadenine,Lentinacin
	Eritadenine is a potent S-adenosyl-L-homocysteine hydrolase (SAHH) inhibitor, decreasing total cholesterol levels in plasma.
T35766	SAHO
	SAHO is a sulfoxide form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and a substrate for radical SAM enzymes.1It is reductively cleaved to S-adenosylhomocysteine , 5'-deoxyadenosine , and 5'-thioadenosine s...
T35767	SAHO2
	SAHO2is a sulfone form of the methyl donor S-(5'-adenosyl)-L-methionine chloride and is a substrate for radical SAM enzymes.1It is reductively cleaved to 5'-deoxyadenosine and 5'-thioadenosine sulfinic acid by the radica...
T11500	GSK3368715	EPZ019997	Histone Methyltransferase
			Histone Methyltransferase
T36869	5'-chloro-5'-Deoxyadenosine (hydrate)
	5'-chloro-5'-Deoxyadenosine (hydrate) is a nucleoside analog used as a substrate in polyketide biosynthesis. S-(5'-adenosyl)-L-methionine can be converted to 5'-chloro-5'-deoxyadenosine in a reaction catalyzed by a SAM-d...
T75389	Catechol O-methyltransferase
	Catechol O-methyltransferase (COMT) is a magnesium-dependent enzyme that mediates the transfer of methyl groups from S-adenosyl methionine to the hydroxyl group on dopamine, thus converting it to 3-methoxytyramine. COMT ...
T36802	Bisubstrate Inhibitor 78
	Bisubstrate inhibitor 78 is an inhibitor of nicotinamide N-methyltransferase (NNMT; IC50= 1.41 μM).1It binds the NNMT active site in the binding pockets for the NNMT substrates S-adenosyl-L-methionine (SAM) and nicotinam...
T37679	3-hydroxy Palmitic Acid
	3-hydroxy Palmitic acid is a form of the 16:0 lipid palmitic acid . The lipid A part of lipopolysaccharides contain various 3-hydroxy fatty acids, making oxylipins such as 3-hydroxy palmitic acid useful as chemical marke...

Compounds

S-Adenosyl-L-methionine (1,4-butanedisulfonate)

T79919

Synonym: Ademetionine (1,4-butanedisulfonate),S-Adenosyl methionine (1,4-butanedisulfonate),AdoMet (1,4-butanedisulfonate)

Target: Endogenous Metabolite

JQEZ5

T7305

Synonym:

Target: Histone Methyltransferase

S-Adenosyl-L-methionine tosylate

T124334

Synonym:

Target:

S-Adenosyl-L-Methionine iodide salt

T124985

Synonym:

Target:

Trifluoromethyl-tubercidin

T67753

Synonym:

Target: Influenza Virus

3-deazaneplanocin A HCl

T6360

Synonym:

Target: Others, Histone Methyltransferase

Mitoguazone

T35617

Synonym: MGBG,Methyl-GAG

Target: Apoptosis, HIV Protease

Eritadenine

T25385

Synonym: Lentysine,D-Eritadenine,Lentinacin

Target: Histone Methyltransferase

5'-chloro-5'-Deoxyadenosine (hydrate)

T36869

Synonym:

Target:

Catechol O-methyltransferase

T75389

Synonym:

Target:

Bisubstrate Inhibitor 78

T36802

Synonym:

Target:

3-hydroxy Palmitic Acid

T37679

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T4447	S-(5'-Adenosyl)-L-methionine tosylate	SAMe,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt	Others
	S-(5'-Adenosyl)-L-methionine tosylate (SAMe) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases [1]. S-(5'-Adenosyl)-L-methioni...		Others
T6752	S-Adenosyl-L-methionine disulfate tosylate	Ademetionine disulfate tosylate	DNA/RNA Synthesis
	S-Adenosyl-L-methionine disulfate tosylate (Ademetionine disulfate tosylate) is the disulfate-tosylate mixed salt of a mixture of diastereoisomers of the ademetionine ions. Ademetionine possesses anti-inflammatory activi...		DNA/RNA Synthesis
T7475	S-Adenosyl-L-methionine	AdoMet,Ademetionine,SAMe,S-Adenosyl methionine	Others , Endogenous Metabolite
	S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.		Others , Endogenous Metabolite
T4116	S-Adenosyl-DL-Methionine	Ademetionine,S-ADENOSYL-L-METHIONINE	Others
	S-Adenosyl-DL-Methionine (Ademetionine) is a ubiquitous methyl donor involved in a wide variety of biological reactions, including those mediated by DNA and protein methyltransferases. SAM reportedly ameliorates depressi...		Others
TN6669	S-(5'-Adenosyl)-L-methionine chloride
	S-(5'-Adenosyl)-L-methionine chloride is a natural product. The catalog number is TN6669 and the CAS number is 24346-00-7. S-(5'-Adenosyl)-L-methionine chloride can be used as a reference standard.
T74497	S-Adenosyl-L-methionine iodide
	S-(5'-Adenosyl)-L-methionine iodide, also known as S-Adenosyl-L-methionine iodide, is a vital methyl donor present in all living organisms [1].
T5066	Nε,Nε,Nε-Trimethyllysine chloride	Lys(Me)3-OH Chloride,Nε,Nε,Nε-Trimethyllysine hydrochloride	Others , Endogenous Metabolite
	Nε,Nε,Nε-Trimethyllysine chloride (Lys(Me)3-OH Chloride) is a methylated derivative of the amino acid lysine. It is a component of histone proteins, a precursor of carnitine and a coenzyme of fatty acid oxidation. Nε,Nε,...		Others , Endogenous Metabolite

天然物製品

S-(5'-Adenosyl)-L-methionine tosylate

T4447

Synonym: SAMe,S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt

Target: Others

S-Adenosyl-L-methionine disulfate tosylate

T6752

Synonym: Ademetionine disulfate tosylate

Target: DNA/RNA Synthesis

S-Adenosyl-L-methionine

T7475

Synonym: AdoMet,Ademetionine,SAMe,S-Adenosyl methionine

Target: Others, Endogenous Metabolite

S-Adenosyl-DL-Methionine

T4116

Synonym: Ademetionine,S-ADENOSYL-L-METHIONINE

Target: Others

S-(5'-Adenosyl)-L-methionine chloride

TN6669

Synonym:

Target:

S-Adenosyl-L-methionine iodide

T74497

Synonym:

Target:

Nε,Nε,Nε-Trimethyllysine chloride

T5066

Synonym: Lys(Me)3-OH Chloride,Nε,Nε,Nε-Trimethyllysine hydrochloride

Target: Others, Endogenous Metabolite

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-00893	AHCY Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Adenosylhomocysteine is a competitive inhibitor of S-adenosyl-L-methionine-dependent methyl transferase reactions; therefore adenosylhomocysteinase may play a key role in the control of methylations via regulation of the...
TMPH-01682	METTL7B Protein, Human, Recombinant (His)	Human	E. coli
	Thiol S-methyltransferase that catalyzes the transfer of a methyl group from S-adenosyl-l-methionine to hydrogen sulfide and other thiol compounds including dithiothreitol, 7alpha-thiospironolactone, L-penicillamine, and...
TMPH-03434	BIO3 Protein, S. cerevisiae, Recombinant (His & Myc)	Saccharomyces cerevisiae	E. coli
	Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM a...
TMPH-00573	DAPA aminotransferase Protein, E. coli, Recombinant (His & Myc)	E. coli	E. coli
	Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM a...
TMPH-01712	TRMT112 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Acts as an activator of both rRNA/tRNA and protein methyltransferases. Together with methyltransferase BUD23, methylates the N(7) position of a guanine in 18S rRNA. The heterodimer with HEMK2/N6AMT1 catalyzes N5-methylat...
TMPY-02340	HNMT Protein, Human, Recombinant (GST)	Human	E. coli
	HNMT (Histamine N-methyltransferase) is a Protein Coding gene. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. HNMT, the major enzyme for the metabol...
TMPY-01265	RIZ1 Protein, Human, Recombinant (GST)	Human	E. coli
	PR domain containing 2, with ZNF domain (PRDM2), also known as zinc finger protein RIZ, is a member of histone methyltransferase (HMT) class enzymes that methylate lysine residues of histones or proteins. HMTs contain a ...
TMPY-01272	RIZ1 Protein, Human, Recombinant	Human	E. coli
	PR domain containing 2, with ZNF domain (PRDM2), also known as zinc finger protein RIZ, is a member of histone methyltransferase (HMT) class enzymes that methylate lysine residues of histones or proteins. HMTs contain a ...
TMPY-01285	METTL11A Protein, Human, Recombinant	Human	E. coli
	Methyltransferase-like protein 11A, also known as METTL11A, is a member of the methyltransferase superfamily and METTL11 family. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a don...
TMPY-01284	METTL11A Protein, Human, Recombinant (GST)	Human	E. coli
	Methyltransferase-like protein 11A, also known as METTL11A, is a member of the methyltransferase superfamily and METTL11 family. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a don...
TMPY-01306	DNMT2 Protein, Human, Recombinant (GST)	Human	Baculovirus-Insect Cells
	DNMT2, also known as tRNA (cytosine-5-)-methyltransferase, DNA methyltransferase homolog HsaIIP, and TRDMT1, is a member of the DNA methyltransferase family of enzymes. DNMT2 enzymes have been widely conserved during evo...