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Search Results for " amylase "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T63750	α-Amylase-IN-1		Antioxidant , Amylase
	α-Amylase-IN-1 is an α-Amylase inhibitor (IC50: 0.5509 μM). α-Amylase-IN-1 has antioxidant activity with an IC50 value of 53.49 μM for scavenging of DPPH free radicals, and can be used in the study of diabetes and oxidat...		Antioxidant , Amylase
T78359	β-Amylase
	β-Amylase exhibits significant starch-degrading activity and is utilized in a range of biochemical studies [1].
T76161	Bacterial α-Amylase
	Bacterial α-Amylase, often employed in biochemical research [1], facilitates the hydrolysis of internal α-1,4-glycosidic bonds within starch, resulting in low molecular weight products such as glucose, maltose, and malto...
T80714	α-Amylase-IN-4
	α-Amylase-IN-4 (Compd 10y) exhibits the highest level of amylase inhibition, demonstrating an IC50 value of 17.83 ± 0.14 μg/mL [1].
T60447	α-Amylase-IN-3
	α-Amylase-IN-3 (Compound 4) is a non-competitive inhibitor of α-Amylase with an IC50 value of 18.04 μM. α-Amylase-IN-3 has radical scavenging activities with IC50 values of 16.04 μM for DPPH and 16.99 μM for ABTS, respec...
T72828	α-Amylase-IN-2
	α-Glucosidase-IN-3, an oxime ester derivative of oleanolic acid (OA), exhibits inhibitory activity against α-glucosidase (IC50 = 1.28 µM) and α-amylase (IC50 = 3.8 µM).
T78878	α-Amylase/α-Glucosidase-IN-5		Glucosidase
	α-Amylase/α-Glucosidase-IN-5 (compound 4l) functions as a dual inhibitor, effectively inhibiting both α-glucosidase (Glucosidase) and α-amylase (Amylases) with IC50 values of 5.96 μM and 1.62 μM, respectively, exhibiting...		Glucosidase
T61706	α-Amylase/α-Glucosidase-IN-2
	α-Amylase/α-Glucosidase-IN-2 (compound 5) exhibits strong inhibition activity towards both α-amylase and α-glucosidase enzymes, with IC 50 values of 13.02 μM and 13.09 μM, respectively. This compound shows promise for in...
T79225	α-Amylase/α-Glucosidase-IN-3		Glucosidase
	α-Amylase/α-Glucosidase-IN-3 (Compound 17) serves as a dual inhibitor targeting both α-Amylase and α-Glucosidase, exhibiting IC50 values of 0.70 μM and 1.10 μM, respectively. It is applicable for type-II diabetes mellitu...		Glucosidase
T60255	α-Amylase/α-Glucosidase-IN-1
	α-Amylase/α-Glucosidase-IN-1 (compound 33) is an effective inhibitor of α-amylase/α-glucosidase with IC 50 s of 2.01, 2.09 μM for α-amylase and α-glucosidase, respectively. Kinetic studies predict that α-Amylase/α-Glucos...
T80715	α-Amylase/α-Glucosidase-IN-6
	α-Amylase/α-Glucosidase-IN-6 (compound 5j) serves as a potent dual inhibitor of both α-amylase and α-glucosidase, exhibiting IC50 values of 17.0 µM and 40.1 µM, respectively. It demonstrates anti-hyperglycemic activities...
T79402	α-Amylase/α-Glucosidase-IN-4		Glucosidase
	α-Amylase/α-Glucosidase-IN-4 (compound 5), a dual inhibitor targeting α-amylase (Amylases) and α-glucosidase (Glucosidase), exhibits potent inhibition with IC50 values of 1.10 μM and 0.15 μM respectively. This compound i...		Glucosidase
T20711	Hemipyocyanine	528-71-2	Amylase
	Hemipyocyanine (528-71-2) is the virulence factor of Gram-negative, aerobic rod bacterium Pseudomonas aeruginosa. Hemipyocyanine is an α-Amylase inhibitor.		Amylase
T0517	Pancreatin	Pancreatic enzymes,pancrelipase	Others
	Pancreatin (pancrelipase) is a mixture of several digestive enzymes secreted by the exocrine cells of the pancreas. It is composed of amylase, lipase and protease.		Others
T73745	Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside
	Ethylidene-4-nitrophenyl-α-D-Maltoheptaoside (pNP-G7), a substrate of α-amylase, is employed to assess α-amylase activity [1].
T78627	Chinese gallotannin		Others
	Chinese gallotannin, a non-specific promiscuous inhibitor of α-amylase, exhibits a K(i) value of 0.82 μg/mL against human salivary α-amylase and shows potential for diabetes research [1].		Others
T24203	Jmv 170	Jmv-170,Jmv170
	Jmv 170 is the C-terminal heptapeptide of cholecystokinin. It has partial agonist CCK activity on pancreatic amylase release.
T25522	Ici 216140	m216140,Ici216140,m 216140,Ici-216140,m-216140
	ICI 216140 is a GRP/bombesin receptor 2 antagonist (IC50: 2 nM in vitro). At 2 mg/kg, it can decrease bombesin-stimulated pancreatic amylase secretion in rats. At 1 mM, it has been proved to attenuate bombesin-stimulated...
TP1241	Adrenocorticotropic Hormone (ACTH) (18-39), human	ACTH (18-39), human
	Adrenocorticotropic Hormone (ACTH) (18-39) is known as the Corticotropin-like Intermediate Lobe Peptide. It stimulates insulin secretion as well as amylase and protein secretion in a dose-dependent manner similar to thos...
TP1916	[D-Phe12,Leu14]-Bombesin
	Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC50 value of 2 μM. Inhibits amylase release in vitro (IC50 = 4 μM) and attenuates bombesin-mediated suppression of food intake in vivo.
T78376	Rimtoregtide
	Rimtoregtide, a polypeptide, markedly attenuates the elevations in blood amylase and lipase levels associated with acute pancreatitis, suggesting its potential utility in the research of pancreatitis and acute pancreatit...
T64230	α-Glucosidase-IN-3
	α-Glucosidase-IN-3 is an oleanolic acid oxime ester derivative targeting α-glucosidase and α-amylase with an IC50 value of 0.35 μM for α-glucosidase.
T36864	GRP (human) (trifluoroacetate salt)
	Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to (Ki = 300 nM) and stimulates amylase secretion in rat pancreatic AR42J cells (EC50 = 0.3 nM). GRP increases proliferation of ...
T37834	G3-CNP
	G3-CNP is a colorimetric substrate for α-amylases.1Upon hydrolysis by α-amylases, 2-chloro-4-nitrophenol is released which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity. G3-CNP has...
T74255	HPA-IN-1
	HPA-IN-1 (Compound 1) serves as a potent and selective inhibitor of human pancreatic α-amylase (HPA), demonstrating specificity with IC50 values of 12.0 μM for HPA and 410.4 μM for α-glucosidase [1].
T75707	BIM-26226
	BIM-26226, a gastrin-releasing peptide, serves as a potent and selective antagonist to the bombesin receptor, effectively inhibiting BN- or GRP-stimulated amylase release with IC50 values in the nanomolar range. It is ut...
T76262L	Cagrilintide acetate
	Cagrilintide acetate, a long-acting acylated amylase analogue and non-selective AMYR/CTR agonist, effectively reduces food intake and induces significant weight loss in a dose-dependent manner, making it a valuable compo...
T79644	Antidiabetic agent 2		Glucosidase
	Compound 56 (Antidiabetic agent 2) is a glucose-uptake promoter that inhibits DPP-4, PTP-1B, α-amylase, and α-glucosidase, with IC50 values of 0.036, 0.042, 0.241, and 0.185 μM, respectively. This agent effectively decre...		Glucosidase
T76461	[Nle8] Somatostatin (1-28)
	[Nle8] Somatostatin (1-28), a derivative of somatostatin (1-28) with norleucine (Nle) substituting for methionine at position 8, enhances amylase release and elevates cyclic AMP levels in pancreatic acini [1].
T37835	2-Chloro-4-nitrophenyl-α-D-glucopyranoside
	Carbohydrates conjugated with 2-chloro-4-nitrophenyl (CNP) serve as chromogenic substrates in assays for enzymes that release CNP from the conjugated carbohydrate. For example, CNP-β-D-maltoheptaoside and CNP-α-maltotrio...
T35669	Neuromedin C (trifluoroacetate salt)
	Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin , somatostatin, and amylase in rats. Neuromedin C is a truncated form of gastrin-releasing peptide...

Compounds

α-Amylase-IN-1

T63750

Synonym:

Target: Antioxidant, Amylase

Bacterial α-Amylase

α-Amylase/α-Glucosidase-IN-5

T78878

Synonym:

Target: Glucosidase

α-Amylase/α-Glucosidase-IN-2

T61706

Synonym:

Target:

α-Amylase/α-Glucosidase-IN-3

T79225

Synonym:

Target: Glucosidase

α-Amylase/α-Glucosidase-IN-1

T60255

Synonym:

Target:

α-Amylase/α-Glucosidase-IN-6

T80715

Synonym:

Target:

α-Amylase/α-Glucosidase-IN-4

Synonym: Pancreatic enzymes,pancrelipase

Target: Others

Ethylidene-4-nitrophenyl-a-D-Maltoheptaoside

Synonym: Jmv-170,Jmv170

Target:

Ici 216140

T25522

Synonym: m216140,Ici216140,m 216140,Ici-216140,m-216140

Target:

Adrenocorticotropic Hormone (ACTH) (18-39), human

TP1241

Synonym: ACTH (18-39), human

Target:

[D-Phe12,Leu14]-Bombesin

GRP (human) (trifluoroacetate salt)

[Nle8] Somatostatin (1-28)

T76461

Synonym:

Target:

2-Chloro-4-nitrophenyl-α-D-glucopyranoside

T37835

Synonym:

Target:

Neuromedin C (trifluoroacetate salt)

T35669

Synonym:

Target:

カタログ番号	製品名	別名	ターゲット
T1136	Amylase	Diastase	Others
	Amylase (Diastase) is any one of a group of enzymes which catalyses the breakdown of starch into maltose.		Others
T19615	α-Amylase		Amylase
	α-Amylase, a hydrolase enzyme, catalyzes the hydrolysis of internal α-1,4-glycosidic linkages in starch, producing glucose and maltose.		Amylase
T7544	Fucoidan		Others
	Fucoidan is found in various species of brown seaweed and algae,with anticancer, antiviral, neuroprotective, immune-modulating.		Others
T3322	Trans-Chalcone	Chalcone,Cinnamophenone,Chalkone	Apoptosis , Others , Antifungal , Fatty Acid Synthase
	trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones.		Apoptosis , Others , Antifungal , Fatty Acid Synthase
TN1041	Quercimeritrin	Quercetin-7-O-beta-D-glucopyranoside	Anti-infection , COX , NO Synthase
	Quercimeritrin (Quercetin-7-O-beta-D-glucopyranoside) has antibacterial activity, it shows promising activity against Staphylococcus aureus.		Anti-infection , COX , NO Synthase
T78501	Glucoamylase
	Glucoamylase, an enzyme obtained from various sources such as plants, animals, and microorganisms, is utilized in industrial applications. It is extensively employed in starch saccharification processes and the brewing a...
TN1788	Isookanin		Amylase
	Isookanin shows strong diphenyl(2,4,6-trinitrophenyl)iminoazanium (DPPH) radical-scavenging activity with the IC50 value of 7.9 ± 0.53 μM. Isookanin is a potent inhibitor of α-amylase (IC50=0.447 mg/ml).		Amylase
T2S1682	Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside	Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,pinocembrin-7-o-3-o-galloyl-4-6-hexahydroxydiphenoyl-beta-d-glucoside	Amylase
	Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside can moderately inhibit α-amylase activity, with the IC50 value of 0.03 umol/ml.		Amylase
TN4368	Kaempferol-3,7-di-O-β-glucoside	Kaempferol 3,7-di-O-glucoside	Glucosidase , Amylase
	Kaempferol-3,7-di-O-β-glucoside (Kaempferol 3,7-diglucoside) is a flavonol from Morettia philaena, It can inhibit α-amylase, α-glucosidase and Acetylcholinesterase. Kaempferol-3, 7-di-o-β-Glucoside has neuroprotective ac...		Glucosidase , Amylase
T5690	7,4'-Di-O-methylapigenin	4',7-DIMETHOXY-5-HYDROXYFLAVONE	Amylase
	7,4'-Di-O-methylapigenin (4',7-DIMETHOXY-5-HYDROXYFLAVONE) can inhibit α-glucosidase and α-amylase enzymes and enhance 2-NBDG uptake in L6 cells, it has hypolipidemic effect on mouse pre-adipocyte (3T3L1) cell lines.		Amylase
T2S0731	Trilobatin	P-Phlorizin	Amylase
	Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentially inhibits the lipopolysaccharide (LPS)-induced inflammatory respon...		Amylase
T3S0013	Ethyl trans-caffeate	Ethyl caffeate,Caffeic Acid Ethyl Ester	Others
	1. Ethyl trans-caffeate (Caffeic Acid Ethyl Ester) has anti-inflammatory activity. 2. Ethyl trans-caffeate may as a promising natural compound for future application in chronic liver disease. 3. Ethyl trans-caffeate is a...		Others
TN4010	Erythrocentaurin		Antifection
	Erythrocentaurin has antibacterial activity; it also exhibits a concentration-dependent α-amylase inhibition (IC(50) 1.67 ± 0.28 mg/mL).		Antifection
T40769	Maltooctaose
	Maltooctaose, a defined maltooligosaccharide with a specific length, can be enzymatically synthesized using Pyrococcus furiosus thermostable amylase (PFTA).
T75701	8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside
	8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside (Compound 3), a natural product isolated from Bidens bipinnata, exhibits a 22% inhibition against α-amylase at a concentration of 0.556 mg/mL [1].
T39219	Ficusonolide
	Ficusonolide exhibits significant antidiabetic activity through its interactions with dipeptidyl peptidase-IV (DPP-IV), protein tyrosine phosphatase 1B (PTP-1B), α-glucosidase, and α-amylase.
T3S0964	Thermopsoside	Chrysoeriol-7-O-glucoside	Others
	Chrysoeriol-7-O-glucoside can strongly inhibit the classical pathway of the complement system.Chrysoeriol-7-O-d-glucoside and luteolin-7-O-d-glucoside can inhibit palmitic acid uptake into small intestinal brush border m...		Others
TN6524	Irilone
	Irilone has immunomodulatory, and α-amylase inhibitory activities, it exhibits the selective inhibition toward CYP3 A4 rather than other major human CYPs. Irilone exhibited prominent antioxidant activities with the IC50 ...
T75492	Ellipyrone A
	Ellipyrone A, a γ-pyrone-based macrocyclic polyketide, demonstrates inhibitory activity against dipeptidyl peptidase-4 (IC 50 = 0.35 mM). Additionally, this compound exhibits anti-glycolytic effects on α-glucosidase (IC ...
T79939	Quercetin 3-(6″-caffeoylsophoroside)
	Quercetin 3-(6″-caffeoylsophoroside) is an orally active compound exhibiting α-amylase inhibitory activity, with an IC50 value of 73.66 μg/mL, and demonstrates antidiabetic effects through the reduction of oxidative stre...
T2S0491	Isoeugenol acetate	Isoeugenyl acetate,Acetisoeugenol,Acetylisoeugenol	AChE , Antifungal
	1. Isoeugenol acetate (Acetylisoeugenol) shows good antifungal activities against R. solani and F. oxysporum. 2. Isoeugenol acetate is a mild sensitizer in vivo.		AChE , Antifungal

天然物製品

Synonym: Chalcone,Cinnamophenone,Chalkone

Target: Apoptosis, Others, Antifungal, Fatty Acid Synthase

Quercimeritrin

TN1041

Synonym: Quercetin-7-O-beta-D-glucopyranoside

Target: Anti-infection, COX, NO Synthase

Pinocembrin 7-O-[3''-O-galloyl-4'',6''-hexahydroxydiphenoyl]-β-D-glucoside

T2S1682

Synonym: Pinocembrin 7-O-(3''-galloyl-4'',6''-(S)-hexahydroxydiphenoyl)-beta-D-glucose,pinocembrin-7-o-3-o-galloyl-4-6-hexahydroxydiphenoyl-beta-d-glucoside

Target: Amylase

Kaempferol-3,7-di-O-β-glucoside

TN4368

Synonym: Kaempferol 3,7-di-O-glucoside

Target: Glucosidase, Amylase

7,4'-Di-O-methylapigenin

T5690

Synonym: 4',7-DIMETHOXY-5-HYDROXYFLAVONE

Synonym: Ethyl caffeate,Caffeic Acid Ethyl Ester

8,3′,4′-Trihydroxyflavone-7-O-β-D-glucopyranoside

Synonym: Chrysoeriol-7-O-glucoside

Quercetin 3-(6″-caffeoylsophoroside)

Synonym: Isoeugenyl acetate,Acetisoeugenol,Acetylisoeugenol

Target: AChE, Antifungal

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-03921	Alpha amylase/AMY2A Protein, Rhesus, Recombinant (His)	Rhesus	HEK293 Cells
	Alpha amylase/AMY2A Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.2 kDa and the accession number is H9EX43.
TMPY-00529	Alpha amylase/AMY2A Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293 Cells
	Alpha amylase/AMY2A Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.8 kDa and the accession number is H9EX43.
TMPY-03107	Alpha amylase/AMY2A Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Alpha amylase/AMY2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.3 kDa and the accession number is P04746.
TMPY-00340	Beta Amylase/AMY2B Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	Beta Amylase/AMY2B Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82.4 kDa and the accession number is P19961-1.
TMPY-00503	Beta Amylase/AMY2B Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Beta Amylase/AMY2B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.3 kDa and the accession number is P19961-1.
TMPH-00078	Beta-amylase 1, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc)	Arabidopsis thaliana	E. coli
	Beta-amylase activity. Can use p-nitrophenyl maltopentaoside (PNPG5) as substrate only in reduced form. Can play a minor role in the starch degradation and maltose metabolism in chloroplasts during the night. More active...
TMPH-00079	Beta-amylase 3, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His)	Arabidopsis thaliana	E. coli
	Beta-amylase activity. No alpha-amylase activity. Involved in cold resistance. Mediates the accumulation of maltose upon freezing stress, thus contributing to the protection of the photosynthetic electron transport chain...
TMPH-01636	MGAM Protein, Human, Recombinant (aa 960-1853, His)	Human	Baculovirus Insect Cells
	May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used...
TMPH-03607	HOE-467A Protein, Streptomyces tendae, Recombinant (His & Myc & SUMO)	Streptomyces tendae	E. coli
	Inhibits mammalian alpha-amylases specifically but has no action on plant and microbial alpha-amylases. Forms a tight stoichiometric 1:1 complex with alpha-amylase. HOE-467A Protein, Streptomyces tendae, Recombinant (His...
TMPH-01635	MGAM Protein, Human, Recombinant (aa 87-954, His)	Human	Baculovirus Insect Cells
	May serve as an alternate pathway for starch digestion when luminal alpha-amylase activity is reduced because of immaturity or malnutrition. May play a unique role in the digestion of malted dietary oligosaccharides used...