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T9353 |
OXOMEMAZINE
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AChR
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Histamine Receptor
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Oxomemazine is a phenothiazine-based histamine H1-receptor blocker with pronounced antimuscarinic activity. Oxomemazine is a selective antagonist of mycotoxins M1 receptors, showing high (Ki=84 nM, M1 receptors) and low ... |
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T8383 |
Cyclopentolate Hydrochloride
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AChR
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Cyclopentolate Hydrochloride is a muscarinic acetylcholine receptors antagonist with Kis of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively. |
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T5023 |
Propiverine hydrochloride
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Others
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Calcium Channel
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AChR
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Propiverine is a widely used antimuscarinic drug with a mixed mode of action in the treatment of symptoms associated with overactive bladder (OAB). |
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T9419 |
Fesoterodine
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(R) Fesoterodine |
AChR
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Fesoterodine ((R) Fesoterodine) is an orally active, competitive mAChR antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. It is used for the overactive bladder (OAB). |
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T0786 |
Clidinium bromide
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Ro 2-3773 |
AChR
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Clidinium bromide (Ro 2-3773) , a synthetic anticholinergic agent, has been shown in experimental and clinical researchers to have a pronounced antisecretory and antispasmodic effect on the gastrointestinal tract. It can... |
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T1475 |
Fesoterodine fumarate
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Toviaz,SPM 907 |
AChR
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Fesoterodine fumarate (Toviaz) is the fumarate salt form of fesoterodine, a competitive muscarinic receptor antagonist with muscle relaxant and urinary antispasmodic properties. Fesoterodine is rapidly hydrolyzed in vivo... |
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T0862 |
Diphenidol hydrochloride
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Diphenidol HCl,Difenidol hydrochloride |
Sodium Channel
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AChR
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Diphenidol hydrochloride (Difenidol hydrochloride), a muscarinic antagonist, is employed as an anti-vertigo and as an antiemetic drug. |
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T2138 |
Oxyphencyclimine Hydrochloride
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Spazamin,Daricon,Ulcociclinina |
AChR
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Oxyphencyclimine Hydrochloride (Ulcociclinina) is a synthetic tertiary amine and antimuscarinic agent with antispasmodic and antisecretory activities. |
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T1474 |
Otilonium bromide
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Octylonium bromide,SP63 |
Calcium Channel
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AChR
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Otilonium bromide (SP63) , an antimuscarinic, is utilized as a spasmolytic agent. |
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T7002 |
Trihexyphenidyl hydrochloride
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Triesifenidile,Benzhexol hydrochloride,Tremin,Artane hydrochloride |
AChR
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Trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is an antiparkinsonian agent of the antimuscarinic class. |
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T7555 |
Piperidolate hydrochloride
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AChR
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Piperidolate hydrochloride is an antimuscarinic, could restrain the abnormal activity caused by acetylcholine. inhibits intestinal cramp induced by acetylcholine (rats and dogs). |
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T0427 |
Homatropine Methylbromide
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Homatropine methobromide |
AChR
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Homatropine Methylbromide is the methyl bromide salt of homatropine, a synthetic tertiary amine alkaloid with antimuscarinic properties. |
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T2222 |
Carbinoxamine Maleate Salt
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Lergefin,CarbinoxaMine Maleate |
Histamine Receptor
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Carbinoxamine Maleate Salt (Lergefin) is an ethanolamine class of H1 antihistamines with mild antimuscarinic and sedative properties. |
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T9420 |
Prifinium bromide
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Others
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Prifinium bromide is a quaternary ammon antimuscarinic. It inhibits hyperkinesia of the digestive organs and urinary tract and has a spasmolytic action. |
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T9877 |
Tiquizium
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AChR
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Tiquizium has effective Antimuscarinic effect, and causes significant bronchodilation in patients with chronic obstructive pulmonary disease. |
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T1197 |
Trimebutine maleate
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Debridat,Polibutin |
Calcium Channel
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Opioid Receptor
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Trimebutine maleate (Polibutin) is a weak mu-opioid agonist and has antimuscarinic effects. Trimebutine is an agonist of peripheral mu, delta, and kappa opiate receptors served as a spasmolytic drug for therapy of both c... |
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T0918 |
Trimebutine
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Mebutin |
Opioid Receptor
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Trimebutine (Mebutin) is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu-opioid agonist effects. It is marketed for the treatment of irritabl... |
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T67956L |
Litoxetine HCl
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litoxetine HCL(86811-09-8 Free base) |
5-HT Receptor
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Litoxetine HCl is a selective 5-hydroxytryptamine (5-HT) reuptake inhibitor (SSRI) and mixed 5-hydroxytryptamine antagonist used in the treatment of urinary incontinence. Litoxetine HCl in the absence of antimuscarinic c... |
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T28523 |
Revatropate
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UK-112 166,UK 112166,UK-112,166 |
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Revatropate, a selective muscarinic antagonist, is an antimuscarinic drug. |
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T11275 |
Fesoterodine L-mandelate
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Others
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Fesoterodine L-mandelate is a efficacious antimuscarinic agent for the overactive bladder (OAB). |
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T0703L |
Flavoxate
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Uronid,Spasuret,Bladuril,Urispas |
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Flavoxate is an anticholinergic with antimuscarinic effects. |
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T31678 |
Espatropate
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UK-88060 |
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Espatropate is a bronchodilator with antimuscarinic activity. |
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T28941 |
Telenzepine
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Telenzepine is a potent and selective M1 antimuscarinic. |
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T34936 |
Tridihexethyl chloride
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Propethonum,Pathilon,Tridihexethyl |
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Tridihexethyl is an anticholinergic, antimuscarinic, and antispasmolytic drug, which can be used to treat acquired nystagmus or peptic ulcer disease. |
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T23998 |
Dihexyverine HCl
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Olimplex,Neospasmina,Diverine,Dihexyverine hydrochloride,Seclin |
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Dihexyverine HCl is an antimuscarinic with effects similar to those of atropine. |
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T23852 |
Caramiphen
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Caramiphen is an antimuscarinic and anticholinergic agent that acts as an antagonist of the NMDA receptor. |
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T0346 |
Camylofine
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Avacan,Acamylophenine,Camylofin,Adopon |
Others
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AChR
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Camylofine (Avacan) is an antimuscarinic, used for relaxing smooth muscle. |
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T69234 |
Piperilate HCl
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Piperilate HCl is an antispasmodic, antimuscarinic agent. It is a muscarinic cholinergic receptor antagonist. |
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T71889 |
Esoxybutynin Chloride
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Esoxybutynin Chloride is (S)-enantiomer of oxybutynin chloride. Esoxybutynin exerts antimuscarinic properties. |
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T71107 |
Caramiphen hydrochloride
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Caramiphen hydrochloride is the salt form of Caramiphne (free base), which is an antimuscarinic and anticholinergic agent. It acts as an antagonist of NMDA receptor. |
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T71268 |
Esoxybutynin Free Base
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Esoxybutynin is S-enantiomer of oxybutynin. Esoxybutynin exerts antimuscarinic properties. Racemic oxybutynin is used clinically to treat urinary incontinence. |
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T61309 |
(R)-Oxybutynin
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(R)-Oxybutynin (Aroxybutynin) is an orally active muscarinic receptor antagonist, which exhibits antimuscarinic, antispasmodic, and anticholinergic activity. This compound, being the (R)-isomer of Oxybutynin, competitive... |
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T61438 |
Propiverine
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Propiverine is a potent antimuscarinic agent that effectively inhibits cellular calcium influx, leading to the reduction of muscle spasm. It exhibits neurotropic and musculotropic effects specifically on the smooth muscl... |
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T35616 |
Migrastatin
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Migrastatin is a bacterial metabolite that has been found inStreptomyceswith antimuscarinic and anticancer activities.1,2It binds to M1-5muscarinic acetylcholine receptors (Kis = >200, 200, 31, 43, and >200 μM, respectiv... |
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T36204 |
Methylatropine (nitrate)
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Methylatropine is an antagonist of muscarinic acetylcholine receptors (IC50= <0.1 nM in a radioligand binding assay using isolated porcine brain membranes) and a derivative of atropine .1,2It reduces acetylcholine-induce... |
