Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Fesoterodine ((R) Fesoterodine) is an orally active, competitive mAChR antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. It is used for the overactive bladder (OAB).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 11,000 | |||
10 mg | 在庫あり | ¥ 18,000 | |||
25 mg | 在庫あり | ¥ 29,500 | |||
50 mg | 在庫あり | ¥ 43,500 | |||
100 mg | 在庫あり | ¥ 63,000 |
説明 | Fesoterodine ((R) Fesoterodine) is an orally active, competitive mAChR antagonist with pKi values of 8.0, 7.7, 7.4, 7.3, 7.5 for M1, M2, M3, M4, M5 receptors, respectively. It is used for the overactive bladder (OAB). |
ターゲット&IC50 | M2 mAChR:7.7(pKi), M3 mAChR:7.4(pKi), M1 mAChR:8.0(pKi) |
In vivo | Fesoterodine (0.01-1 mg/kg; i.v.) reduces the micturition pressure and increases bladder capacity and ICIs (intercontraction intervas) at the lowest dose tested of 0.01 mg/kg [3]. |
別名 | (R) Fesoterodine |
分子量 | 411.58 |
分子式 | C26H37NO3 |
CAS No. | 286930-02-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 50 mg/mL (121.48 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Fesoterodine 286930-02-7 Neuroscience AChR Desfesoterodine OAB muscarinic overactive Inhibitor (R) Fesoterodine SPM7605 mAChR orally 5-HMT antimuscarinic bladder Muscarinic acetylcholine receptor inhibit receptor inhibitor