|
T8348 |
Phentolamine
|
|
Adrenergic Receptor
|
|
Phentolamine mesylate is an alpha-1 and alpha-2 selective adrenergic receptor antagonist |
|
T8485 |
THIQ
|
|
Melanocortin Receptor
|
|
THIQ is a selective melanocortin-4 receptor (MC4R) agonist (hMC4R and rMC4R with IC50 of 1.2 nM and 0.6 nM , respectively). |
|
T8405 |
Vardenafil hydrochloride
|
|
PDE
|
|
Vardenafil hydrochloride is a New Phosphodiesterase Type 5(PDE5) Inhibitor, in the Treatment of Erectile Dysfunction in Men With Diabetes |
|
T0096 |
Vardenafil
|
Vivanza,Levitra,Vardenafil hydrochloride |
PDE
|
|
|
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T4612 |
NS309
|
|
EGFR
,
Potassium Channel
,
HER
|
|
NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK channels and 10-90 nM for IK channels). It can also activat... |
|
T4097 |
Vardenafil hydrochloride trihydrate
|
Vardenafil HCl Trihydrate,BAY38-9456 |
PDE
|
|
Vardenafil hydrochloride trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively. |
|
T1275 |
Phentolamine mesylate
|
Phentolamine methanesulfonate,Phentolamine mesilate |
Adrenergic Receptor
|
|
Phentolamine mesylate (Phentolamine methanesulfonate) is a nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEAS... |
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T2334 |
Avanafil
|
TA1790 |
PDE
|
|
Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction. |
|
T16079 |
Mirodenafil
|
SK3530 |
PDE
|
|
Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction. |
|
TQ0126 |
Mirodenafil dihydrochloride
|
SK-3530 dihydrochloride |
PDE
|
|
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction. |
|
T4480 |
Vardenafil dihydrochloride
|
Levitra,Vardenafil Hydrochloride |
PDE
|
|
Vardenafil dihydrochloride (Levitra) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively. |
|
T27122 |
Dasantafil
|
SCH446132,SCH-446132,SCH 446132 |
PDE
|
|
Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction. |
|
T0467 |
Sildenafil citrate
|
UK-92480 citrate |
Apoptosis
,
PDE
,
Autophagy
|
|
Sildenafil citrate (UK-92480 citrate) , a cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) Inhibitor, is used extensively for erectile dysfunction and less commonly for pulmonary hypertensio... |
|
TP1097 |
Melanotan I
|
[Nle4,D-Phe7]-α-MSH,Afamelanotide,MT-I |
Others
|
|
Melanotan I is a non-specific melanocortin receptor (MCR) agonist, an α-melanocyte-stimulating hormone (α-MSH) analog, which is injected subcutaneously to increase the amount of melanin in the skin Melanotan I is used as... |
|
T7346 |
Lodenafil
|
Hydroxyhomosildenafil |
PDE
|
|
Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED) |
|
T6147 |
Nortadalafil
|
Demethyl Tadalafil |
PDE
|
|
Nortadalafil (Demethyl Tadalafil) is demethyl Tadalafil, which is a PDE5 inhibitor, treating erectile dysfunction (ED) ; and under the name Adcirca for the treatment of pulmonary arterial hypertensio. |
|
T9847 |
TLC2976-0103
|
|
|
|
ROCK1-IN-1 is an inhibitor of ROCK1 with a K i value of 540 nM. ROCK1-IN-1 can be used in the research of hypertension, glaucoma and erectile dysfunction [1]. |
|
T22019 |
ABT 724 trihydrochloride
|
|
Dopamine Receptor
|
|
ABT 724 trihydrochloride is an effective and selective agonist of the D4 receptor (EC50 = 12.4 nM, 14.3 nM, and 23.2 nM for human, rat and ferret, respectively). ABT-724 trihydrochloride can be used in erectile dysfuncti... |
|
T29048 |
UK 357903
|
UK357903,UK-357903 |
|
|
UK 357903, a phosphodiesterase 5A (PDE5A) inhibitor, is used potentially for the treatment of erectile dysfunction. |
|
TP1016 |
Aviptadil
|
Vasoactive Intestinal Peptide (human, rat, mouse, rabbit, canine, porcine) |
|
|
Aviptadil (INN) is an analog of vasoactive intestinal polypeptide (VIP) for the treatment of erectile dysfunction. |
|
T29194 |
Yonkenafil HCl
|
Yonkenafil hydrochloride |
|
|
Yonkenafil HCl, a PDE5 inhibitor, is used potentially for the treatment of erectile dysfunction. |
|
T79091 |
Bivamelagon hydrochloride
|
MC-4R Agonist 2 hydrochloride |
Melanocortin Receptor
|
|
MC-4R Agonist 2 hydrochloride (Example 1) serves as an MC4R agonist, with applications in researching obesity, diabetes, inflammation, and erectile dysfunction. [1] |
|
T83536 |
(R)-Avanafil
|
(R)-TA1790 |
|
|
(R)-Avanafil ((R)-TA1790) is a selective phosphodiesterase type 5 (PDE5) inhibitor with an IC50 of 5.2 nM, utilized for the research of erectile dysfunction [1]. |
|
T70019 |
Tadalafil hydroxypiperidone
|
|
|
|
Tadalafil hydroxypiperidone is an impurity of Tadalafil -- a phosphodiesterase 5-inhibitor used for the treatment of erectile dysfunction. |
|
T70629 |
Acetaminotadalafil
|
|
|
|
Acetaminotadalafil is a new analogue of Tadalafil used for the treatment of erectile dysfunction. It acts as a phosphodiesterase 5 inhibitor. |
|
T73473 |
TPN729
|
|
|
|
TPN729, a selective inhibitor of phosphodiesterase type 5 (PDE5), demonstrates potent activity with an IC50 of 2.28 nM. Primarily impacting erectile function, this compound holds significant potential for erectile dysfun... |
|
T20024 |
Tadalafil, (6R ,12aS)-
|
Tadalafil (6R ,12aS)- Lilly,Tadalafil specified impurity A,(-)-Tadalafil (6R ,12aS) diastereomer |
|
|
Tadalafil is a carboline derivative and Phosphodiesterase 5 Inhibitor. It is used primarily to treat Erectile dysfunction, Benign Prostatic Hyperplasia, and Primary Pulmonary Hypertension. |
|
T73354 |
TPN729MA
|
TPN729 maleate |
|
|
TPN729MA (TPN729 maleate), a selective phosphodiesterase type 5 (PDE5) inhibitor, exhibits potent activity with an IC50 value of 2.28 nM and has applications in researching erectile dysfunction by impacting erectile func... |
|
T37325 |
Lodenafil carbonate
|
|
|
|
Lodenafil carbonate, a prodrug dimer that delivers Lodenafil in vivo, is an orally active inhibitor of phosphodiesterase type 5 (PDE5), indicated for the treatment of erectile dysfunction (ED)[1][2]. |
|
T74372 |
N-Desalkyludenafil
|
|
|
|
N-Desalkyludenafil, a metabolite of Udenafil, functions as a PDE5 inhibitor and is utilized in the study of erectile dysfunction [1]. |
|
T69127 |
Moxisylyte
|
|
|
|
Moxisylyte, also known as thymoxamine, is a drug used in urology for the treatment of erectile dysfunction. It is an α1-adrenergic antagonist. Moxisylyte is also used for the short-term treatment of primary Reynaud's syn... |
|
T79090 |
Bivamelagon
|
MC-4R Agonist 2 |
Melanocortin Receptor
|
|
MC-4R Agonist 2 (Example 1), a melanocortin 4 receptor (MC4R) agonist, is employed in the research of conditions such as obesity, diabetes, inflammation, and erectile dysfunction [1]. |
