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T38238 |
2'-Deoxy-2'-fluorocytidine
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Nucleoside Antimetabolite/Analog
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Influenza Virus
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2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency o... |
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T11281L |
FGI-106 tetrahydrochloride
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Virus Protease
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HCV Protease
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Influenza Virus
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HIV Protease
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T1414 |
Sodium 2-mercaptoethanesulfonate
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Mitexan,Uromitexan,Mesna,Mesnum,Mesnex |
Others
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Sodium 2-mercaptoethanesulfonate (Uromitexan) is a sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from antineoplastic agents, such as ifosfamide or cyclophosphamide. |
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T5963 |
Menadione bisulfite sodium
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Sodium menadione bisulfite,Menadione sodium bisulfite,Vitamin K3 sodium bisulfite |
Others
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Menadione bisulfite sodium (Vitamin K3 sodium bisulfite) is used clinically in China to treat hemorrhagic diseases caused by vitamin K deficiency and globally as a vitamin K supplement. |
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T12001 |
Menaquinone-7
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Vitamin MK-7,Vitamin K2-7,Vitamin K2(35) |
Others
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Menaquinone-7 (Vitamin K2(35)) is a vitamin K2 analog, is originally discovered as the anti-hemorrhagic factors. Menaquinone-7 (Vitamin K2(35)) is identified as the most bioactive cofactor for the carboxylation reaction ... |
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T21967 |
MEG hemisulfate
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Mercaptoethylguanidine hemisulfate |
NOS
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MEG hemisulfate (Mercaptoethylguanidine hemisulfate) acts as a highly potent and selective suppressor of inducible NO synthase (iNOS), demonstrating EC50 values of 11.5 μM for iNOS, 110 μM for ecNOS, and 60 μM for bNOS i... |
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T31564 |
Dopamine, lys-pro-amide-
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Dopamine, lys-pro-amide- is equieffective to dopamine as to its protective activity against hemorrhagic shock. |
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T77140 |
Ralpancizumab
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Ralpancizumab, a selective PCSK9 inhibitor, shows potential for use in hemorrhagic stroke [1]. |
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T27590 |
IHVR-11029
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IHVR 11029 |
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IHVR-11029 is a potent inhibitor of ER α-glucosidase. IHVR-11029 is active against multiple hemorrhagic fever viruses and efficiently disrupts the morphogenesis of a broad spectrum of enveloped viruses. |
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T15554 |
IHVR-19029
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Others
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IHVR-19029 is an effective endoplasmic reticulum (ER) α-glucosidases I and II inhibitor (IC50: 0.48 μM for ER a-glucosidase I). IHVR-19029 efficiently blocks the replication of several hemorrhagic fever viruses, such as ... |
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T26589 |
Albifylline
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Albifylline is a xanthine derivates with anti-asthmatic activity. Albifylline may cause a significant reduction of shock-induced leukocyte adhesions to the sinusoidal endothelium in the liver after hemorrhagic shock. Alb... |
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T27050 |
CM-10-18
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CM-1018 |
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CM-10-18 is a potent inhibitor of ER α-glucosidase. CM-10-18 demonstrated superior in vitro antiviral activity against representative viruses from four viral families causing hemorrhagic fever. CM-10-18 efficiently prote... |
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T11281 |
FGI-106
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Others
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FGI-106 is a potent, broad-spectrum inhibitor demonstrating activity against various viruses, including Ebola, Rift Valley Fever, and Dengue Fever, exhibiting EC50 values of 100 nM, 800 nM, and 400-900 nM, respectively. ... |
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T70838 |
RO27-3225 TFA
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RO27-3225, also known as RO273225 is a melanocortin type 4 receptor agonist with EC50 = 1 nM. It may alleviate intestinal dysfuntion and brain damage. It has been investigated for an anti-obesity medication. Ro 27-3225... |
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T80341 |
Seabream hepcidin
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Seabream hepcidin, an antimicrobial peptide, exhibits antibacterial (V. anguillarum), antifungal (S. cerevisiae), and antiviral activities against hemorrhagic septicemia virus [1]. |
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T77166 |
Rovelizumab
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Rovelizumab, a humanized monoclonal leukointegrin antibody, targets CD11/CD18 cell adhesion proteins. It has potential applications in the research of multiple sclerosis (MS), hemorrhagic shock, myocardial infarction (MI... |
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T80154 |
TAT-CIRP
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TAT-CIRP, a trans-activating (Tat) cold-inducible RNA-binding protein-derived peptide, functions as an inhibitor of myeloid differentiation protein 2 (MD2). It has demonstrated significant neuroprotective effects against... |
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T78586 |
Ac-IETD-CHO
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Apoptosis
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Ac-IETD-CHO is a potent, reversible inhibitor of granzyme B and caspase 8, which also impedes Fas-mediated apoptosis, hemorrhagic conditions, and liver failure. Furthermore, this compound hampers cell death induced by cy... |
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TP2184 |
Matrix protein (3-15) [Zaire ebolavirus]
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Others
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matrix protein (3-15) [Zaire ebolavirus] is a peptide of the structural proteins linking the viral envelope with the zaire ebolavirus core. Ebola virus (EBOV) is a member of the family Filoviridae in the order Mononegavi... |
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T75847 |
PG-931 TFA
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PG-931 TFA, a potent and selective agonist of the melanocortin 4 (MC4) receptor (IC50=0.58 nM) compared to the hMC3R (IC50=55 nM) and hMC5R (IC50=2.4 nM), is an analog of SHU 9119. This compound has demonstrated efficacy... |
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T38043 |
Resolvin E4
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Resolvin E4 (RvE4) is a member of the specialized pro-resolving mediator (SPM) family of bioactive lipids.1It is produced from eicosapentaenoic acid by 15-lipoxygenase (15-LO)via15(S)-HpEPE and 15S-hydroxy, 5S-HpEPE inte... |
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T38297 |
Ribavirin-13C5
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Ribavirin-13C5 |
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Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to a... |
