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Search Results for " insulin-sensitizing "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T28501	Ragaglitazar	NNC61-0029,NN-622,(-)-DRF-2725,NNC-61-0029,NN 622,NNC 61-0029	PPAR
	Ragaglitazar(NNC-61-0029) is a potent dual PPARα and PPARγ agonist that has shown potent lipid-lowering and insulin sensitizing effects in animal models.Ragaglitazar can be used to study type 2 diabetes.		PPAR
T0214	Pioglitazone	U 72107	Ferroptosis , PPAR
	Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione that is indicated for the treatment of type 2 diabetes. Pioglitazone has been linked to rare instances of acute liver injury.		Ferroptosis , PPAR
T69633	TCS-401
	TCS-401 is an insulin receptor sensitizing agent; Selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B).
T21812	LT175
	LT175, a dual PPARα/γ ligand, demonstrates potent insulin-sensitizing effects while exhibiting reduced adipogenic properties. This compound is an orally active partial agonist targeting PPARγ, with EC50 values of 0.22 μm...

Compounds

Ragaglitazar

T28501

Synonym: NNC61-0029,NN-622,(-)-DRF-2725,NNC-61-0029,NN 622,NNC 61-0029

Target: Ferroptosis, PPAR

カタログ番号	製品名	別名	ターゲット
T6368	Abscisic Acid	Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin）	Others , Proton pump , Endogenous Metabolite
	Abscisic Acid (Dormin) is a plant hormone, which is involved in many plant developmental processes, modulates ion homeostasis and metabolism, and inhibits germination and seedling growth.		Others , Proton pump , Endogenous Metabolite
T5431	[10]-Shogaol	10-Shogaol	Antioxidant , COX
	[10]-Shogaol (10-Shogaol) is an extract from ginger displaying antioxidant activity. It also may contain hypolipidemic and insulin-sensitizing effects.		Antioxidant , COX
T5S0620	3-Dehydrotrametenolic acid	Dehydrotrametenolic acid	Apoptosis , Others , Dehydrogenase
	1. 3-Dehydrotrametenolic acid can be a potential anticancer agent against H-ras transformed tumor. 2. Dehydrotrametenolic acid is a promising candidate for a new type of insulin-sensitizing drug.		Apoptosis , Others , Dehydrogenase
T2S2173	(E)-Naringenin chalcone	Isosalipurpol,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone	Others
	Naringenin chalcone (Isosalipurpol) has antiallergic activity Naringenin chalcone suppresses asthmatic symptoms by inhibiting Th2 cytokine production from CD4 T cells. Naringenin chalcone is a potent tomato flavonoid tha...		Others

天然物製品

Abscisic Acid

T6368

Synonym: Abscisin II,Dormin,(+)-ABA,Abscisic Acid (Dormin）

Target: Others, Proton pump, Endogenous Metabolite

[10]-Shogaol

T5431

Synonym: 10-Shogaol

Target: Antioxidant, COX

3-Dehydrotrametenolic acid

T5S0620

Synonym: Dehydrotrametenolic acid

Target: Apoptosis, Others, Dehydrogenase

(E)-Naringenin chalcone

T2S2173

Synonym: Isosalipurpol,Chalconaringenin,trans-2'4'6'4-tetrahydroxychalcone

Target: Others

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-02496	Adipolin Protein, Mouse, Recombinant (E. coli, His)	Mouse	E. coli
	Adipolin Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 37.0 kDa and the accession number is Q8R2Z0.
TMPH-02497	Adipolin Protein, Mouse, Recombinant (His)	Mouse	Baculovirus Insect Cells
	Adipolin Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 33.9 kDa and the accession number is Q8R2Z0.
TMPJ-00262	Serpin A12 Protein, Human, Recombinant (GST)	Human	E. coli
	Vaspin (Visceral Adipose-Specific SERPIN) is a newly described adipokine. Vaspin has three β-sheets, nine α-helices, and one central loop; the structure is part of the set of distinctive features that are descriptive of ...

Adipolin Protein, Mouse, Recombinant (E. coli, His)

TMPH-02496

Species: Mouse

Expression System: E. coli

Adipolin Protein, Mouse, Recombinant (His)

TMPH-02497

Species: Mouse

Expression System: Baculovirus Insect Cells

Serpin A12 Protein, Human, Recombinant (GST)

TMPJ-00262

Species: Human

Expression System: E. coli