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Search Results for " integration "

ターゲット

13

阻害剤

14

リコンビナントタンパク質

2

ライブラリー

カタログ番号 製品名 別名 ターゲット
T12575 Unesbulin PTC596 Apoptosis , BMI-1
Unesbulin (PTC596) is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1).
T60742 HIV-1 integrase inhibitor 8 HIV Protease
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1].
T35617 Mitoguazone MGBG,Methyl-GAG Apoptosis , HIV Protease
Mitoguazone (Methyl-GAG) is a selective S-adenosyl-methionine decarboxylase inhibitor that penetrates the blood-brain barrier and disrupts polyamine biosynthesis. Mitoguazone is a synthetic polycarbonyl derivative with a...
T71786 CID-1304264
CID-1304264 is an HIV-1 Rev pre-integration inhibitor.
T68364 GS-9160
GS-9160 is a novel and potent inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase (IN) that specifically targets the process of strand transfer. It is an authentic inhibitor of HIV-1 integration, since tre...
T38896 VPM peptide
VPM peptide functions as a protease-cleavable dithiol cross-linker. It is capable of integration into the PEG-diacrylate (PEG-DA) macromer backbone, resulting in the formation of PEG hydrogel.
T26968 CCT036477 CCT 036477,CCT-036477
CCT036477 is a selective inhibitor of wingless-type MMTV integration site family dependent transcription. CCT036477reduces the transcriptional activity of the T-cell factor and lymphoid enhancer factor transcription fact...
T18473 N3-PEG3-vc-PAB-MMAE Others
N3-PEG3-vc-PAB-MMAE, a drug-linker conjugate designed for Antibody-Drug Conjugates (ADC), features the integration of monomethyl auristatin E (MMAE), a tubulin inhibitor, via a 3-unit polyethylene glycol (PEG) linker. Th...
T69782 GS-9822
GS-9822 is a novel LEDGIN, an inhibitor that targets the binding pocket of LEDGF/p75 which is a cellular cofactor that substantially contributes to HIV integration site selection, displaying a block-and-lock phenotype in...
T82894 BETA-1
BETA-1, a twisted intramolecular charge transfer (TICT)-aggregation-induced emission (AIE) integration molecule, exhibits cyan fluorescence in lipid droplets (LDs) and red fluorescence in mitochondria, facilitating the d...
T64096 Integrase-LEDGF/p75 allosteric inhibitor 1
Integrase-LEDGF/p75 allosteric inhibitor 1 is an orally active integrase-LEDGF/p75 (IN-LEDGF/p75) allosteric inhibitor. It inhibits HIV-1 DNA integration and exhibits antiviral effects, acting on the HIV-1 recombinant mo...
T78059 Glucagon (Human) Hyperglycemic-glycogenolytic factor,Glukagon Others
Glucagon significantly impacts protein and amino acid metabolism. It hinders the integration of amino acids into the proteins of the liver, muscle, and pancreas, augmenting nitrogen excretion and stimulating hepatic urea...
T83958 CELT-327
CELT-327 is a potent, selective fluorescent hA2B/A3 adenosine receptor antagonist, exhibiting K_i values of 35.6 nM at A2B and 45.7 nM at A3 receptors. It efficiently labels HCT116 cells expressing A2B adenosine receptor...

Recombinant Proteins

カタログ番号 製品名 Species Expression System
TMPY-03210 EVI2A Protein, Human, Recombinant (hFc) Human HEK293 Cells
EVI2A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.2 kDa and the accession number is P22794-1.
TMPY-06917 PU.1/SPI1 Protein, Human, Recombinant (His) Human E. coli
PU.1/SPI1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 32.04 kDa and the accession number is P17947.
TMPY-06912 PU.1/SPI1 Protein, Mouse, Recombinant (His) Mouse E. coli
PU.1/SPI1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 32.31 kDa and the accession number is P17433.
TMPH-03041 IHF-alpha Protein, MenB, Recombinant (His) MenB E. coli
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control.
TMPH-03042 IHF-beta Protein, MenB, Recombinant (His) MenB E. coli
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. IHF-beta Protein, MenB, ...
TMPH-00755 Integrase Protein, Escherichia phage lambda, Recombinant (His) Escherichia phage lambda E. coli
Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. Int...
TMPH-00317 BipD Protein, Burkholderia pseudomallei, Recombinant (His & Myc) Burkholderia pseudomallei E. coli
Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and th...
TMPK-00957 MFAP5 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-assoc...
TMPK-01217 MFAP5 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-assoc...
TMPH-01522 HIV-2 (subtype A, isolate ROD) Protein Vpx (His) HIV-2 P. pastoris (Yeast)
Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by...
TMPH-00028 Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP) AAV-2 E. coli
Plays an essential role in the initiation of viral DNA synthesis. Binds specifically to an inverted terminal repeat element (ITR) on the 3' and 5' ends of the viral DNA, where it cleaves a site specifically to generate a...
TMPY-04554 JNK1 Protein, Human, Recombinant (GST) Human Baculovirus Insect Cells
Mitogen-activated protein kinase 8 (MAPK8), also known as JNK1, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellula...
TMPY-04260 P38 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as prol...
TMPH-00616 DNA-binding protein H-NS Protein, E. coli, Recombinant (His) E. coli E. coli
A DNA-binding protein implicated in transcriptional repression (silencing). Also involved in bacterial chromosome organization and compaction. H-NS binds tightly to AT-rich dsDNA and inhibits transcription. Binds upstrea...
EVI2A Protein, Human, Recombinant (hFc)
TMPY-03210
Species: Human
Expression System: HEK293 Cells
PU.1/SPI1 Protein, Human, Recombinant (His)
TMPY-06917
Species: Human
Expression System: E. coli
PU.1/SPI1 Protein, Mouse, Recombinant (His)
TMPY-06912
Species: Mouse
Expression System: E. coli
IHF-alpha Protein, MenB, Recombinant (His)
TMPH-03041
Species: MenB
Expression System: E. coli
IHF-beta Protein, MenB, Recombinant (His)
TMPH-03042
Species: MenB
Expression System: E. coli
Integrase Protein, Escherichia phage lambda, Recombinant (His)
TMPH-00755
Species: Escherichia phage lambda
Expression System: E. coli
BipD Protein, Burkholderia pseudomallei, Recombinant (His & Myc)
TMPH-00317
Species: Burkholderia pseudomallei
Expression System: E. coli
MFAP5 Protein, Human, Recombinant (hFc)
TMPK-00957
Species: Human
Expression System: HEK293 Cells
MFAP5 Protein, Mouse, Recombinant (hFc)
TMPK-01217
Species: Mouse
Expression System: HEK293 Cells
HIV-2 (subtype A, isolate ROD) Protein Vpx (His)
TMPH-01522
Species: HIV-2
Expression System: P. pastoris (Yeast)
Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP)
TMPH-00028
Species: AAV-2
Expression System: E. coli
JNK1 Protein, Human, Recombinant (GST)
TMPY-04554
Species: Human
Expression System: Baculovirus Insect Cells
p38 Protein, Human, Recombinant (His)
TMPY-04260
Species: Human
Expression System: Baculovirus Insect Cells
DNA-binding protein H-NS Protein, E. coli, Recombinant (His)
TMPH-00616
Species: E. coli
Expression System: E. coli
カタログ番号 製品名
L8110 Reprogramming Compound Library

1813 compounds
A unique collection of 1813 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening.
L6210 Tibetan medicine Compound Library

747 compounds
A collection of 747 natural product molecules originated from Tibetan medicine, which can be used for high-throughput and high-content screening.