13
14
2
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T12575 | Unesbulin | PTC596 | Apoptosis , BMI-1 |
Unesbulin (PTC596) is an orally active and selective inhibitor of B-cell-specific Moloney murine leukemia virus integration site 1 (BMI-1). | |||
T60742 | HIV-1 integrase inhibitor 8 | HIV Protease | |
HIV-1 integrase inhibitor 8 is an inhibitor of HIV-1 integrase. Integration is a required step in HIV replication [1]. | |||
T35617 | Mitoguazone | MGBG,Methyl-GAG | Apoptosis , HIV Protease |
Mitoguazone (Methyl-GAG) is a selective S-adenosyl-methionine decarboxylase inhibitor that penetrates the blood-brain barrier and disrupts polyamine biosynthesis. Mitoguazone is a synthetic polycarbonyl derivative with a... | |||
T71786 | CID-1304264 | ||
CID-1304264 is an HIV-1 Rev pre-integration inhibitor. | |||
T68364 | GS-9160 | ||
GS-9160 is a novel and potent inhibitor of human immunodeficiency virus type 1 (HIV-1) integrase (IN) that specifically targets the process of strand transfer. It is an authentic inhibitor of HIV-1 integration, since tre... | |||
T38896 | VPM peptide | ||
VPM peptide functions as a protease-cleavable dithiol cross-linker. It is capable of integration into the PEG-diacrylate (PEG-DA) macromer backbone, resulting in the formation of PEG hydrogel. | |||
T26968 | CCT036477 | CCT 036477,CCT-036477 | |
CCT036477 is a selective inhibitor of wingless-type MMTV integration site family dependent transcription. CCT036477reduces the transcriptional activity of the T-cell factor and lymphoid enhancer factor transcription fact... | |||
T18473 | N3-PEG3-vc-PAB-MMAE | Others | |
N3-PEG3-vc-PAB-MMAE, a drug-linker conjugate designed for Antibody-Drug Conjugates (ADC), features the integration of monomethyl auristatin E (MMAE), a tubulin inhibitor, via a 3-unit polyethylene glycol (PEG) linker. Th... | |||
T69782 | GS-9822 | ||
GS-9822 is a novel LEDGIN, an inhibitor that targets the binding pocket of LEDGF/p75 which is a cellular cofactor that substantially contributes to HIV integration site selection, displaying a block-and-lock phenotype in... | |||
T82894 | BETA-1 | ||
BETA-1, a twisted intramolecular charge transfer (TICT)-aggregation-induced emission (AIE) integration molecule, exhibits cyan fluorescence in lipid droplets (LDs) and red fluorescence in mitochondria, facilitating the d... | |||
T64096 | Integrase-LEDGF/p75 allosteric inhibitor 1 | ||
Integrase-LEDGF/p75 allosteric inhibitor 1 is an orally active integrase-LEDGF/p75 (IN-LEDGF/p75) allosteric inhibitor. It inhibits HIV-1 DNA integration and exhibits antiviral effects, acting on the HIV-1 recombinant mo... | |||
T78059 | Glucagon (Human) | Hyperglycemic-glycogenolytic factor,Glukagon | Others |
Glucagon significantly impacts protein and amino acid metabolism. It hinders the integration of amino acids into the proteins of the liver, muscle, and pancreas, augmenting nitrogen excretion and stimulating hepatic urea... | |||
T83958 | CELT-327 | ||
CELT-327 is a potent, selective fluorescent hA2B/A3 adenosine receptor antagonist, exhibiting K_i values of 35.6 nM at A2B and 45.7 nM at A3 receptors. It efficiently labels HCT116 cells expressing A2B adenosine receptor... |
カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-03210 | EVI2A Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
EVI2A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 38.2 kDa and the accession number is P22794-1. | |||
TMPY-06917 | PU.1/SPI1 Protein, Human, Recombinant (His) | Human | E. coli |
PU.1/SPI1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 32.04 kDa and the accession number is P17947. | |||
TMPY-06912 | PU.1/SPI1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
PU.1/SPI1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 32.31 kDa and the accession number is P17433. | |||
TMPH-03041 | IHF-alpha Protein, MenB, Recombinant (His) | MenB | E. coli |
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. | |||
TMPH-03042 | IHF-beta Protein, MenB, Recombinant (His) | MenB | E. coli |
This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. IHF-beta Protein, MenB, ... | |||
TMPH-00755 | Integrase Protein, Escherichia phage lambda, Recombinant (His) | Escherichia phage lambda | E. coli |
Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome. Int... | |||
TMPH-00317 | BipD Protein, Burkholderia pseudomallei, Recombinant (His & Myc) | Burkholderia pseudomallei | E. coli |
Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and th... | |||
TMPK-00957 | MFAP5 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-assoc... | |||
TMPK-01217 | MFAP5 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Human basal-like breast cancer (BLBC) is an aggressive malignancy with poor prognosis. Since most current treatments are ineffective, there is an urgent need to identify therapeutic targets for BLBC. Microfibrillar-assoc... | |||
TMPH-01522 | HIV-2 (subtype A, isolate ROD) Protein Vpx (His) | HIV-2 | P. pastoris (Yeast) |
Plays a role in nuclear translocation of the viral pre-integration complex (PIC), thus is required for the virus to infect non-dividing cells. Targets specific host proteins for degradation by the 26S proteasome. Acts by... | |||
TMPH-00028 | Adeno-associated virus 2 (isolate Srivastava/1982) Rep78 Protein (His & MBP) | AAV-2 | E. coli |
Plays an essential role in the initiation of viral DNA synthesis. Binds specifically to an inverted terminal repeat element (ITR) on the 3' and 5' ends of the viral DNA, where it cleaves a site specifically to generate a... | |||
TMPY-04554 | JNK1 Protein, Human, Recombinant (GST) | Human | Baculovirus Insect Cells |
Mitogen-activated protein kinase 8 (MAPK8), also known as JNK1, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellula... | |||
TMPY-04260 | P38 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as prol... | |||
TMPH-00616 | DNA-binding protein H-NS Protein, E. coli, Recombinant (His) | E. coli | E. coli |
A DNA-binding protein implicated in transcriptional repression (silencing). Also involved in bacterial chromosome organization and compaction. H-NS binds tightly to AT-rich dsDNA and inhibits transcription. Binds upstrea... |
カタログ番号 | 製品名 | ||
---|---|---|---|
L8110 | Reprogramming Compound Library | 1813 compounds | |
A unique collection of 1813 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening. | |||
L6210 | Tibetan medicine Compound Library | 747 compounds | |
A collection of 747 natural product molecules originated from Tibetan medicine, which can be used for high-throughput and high-content screening. |