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T5051 |
Isopropamide Iodide
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|
AChR
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Isopropamide iodide is a long-acting anticholinergic drug. It is used in the treatment of peptic ulcers and other gastrointestinal disorders. It also acts as a muscarinic receptor antagonist which can be applied to the t... |
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T38612 |
Linaprazan glurate
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|
Others
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Linaprazan glurate inhibits exogenously or endogenously stimulated gastric acid secretion. Linaprazan glurate can be used in studies about gastrointestinal inflammatory diseases and peptic ulcer diseases. |
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T4981 |
Anisotropine Methylbromide
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|
Prostaglandin Receptor
,
AChR
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Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion. |
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T15500 |
HPi1
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Others
,
Antibacterial
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HPi1 is a selective and orally active antimicrobial against Helicobacter pylori (IC50: 0.24 μM and a MIC of 0.08-0.16 μg/mL). HPi1 is inactive against other Xaliproden, including the gut commensals, Lactobacillus reuteri... |
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T0044 |
Oxethazaine
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Oxetacaine |
HBV
,
Sodium Channel
|
|
Oxethazaine (Oxetacaine), a topical anesthetic, is used to prevent acid-induced esophageal pain. |
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T1734 |
Rabeprazole Sulfide
|
Rabeprazole Related Compound E |
Proton pump
,
Antibacterial
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Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors. |
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T0992 |
Carbenoxolone disodium
|
Biogastrone,Duogastrone,Bioral |
Gap Junction Protein
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Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, ... |
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T8388 |
Vonoprazan
|
TAK-438 (free base) |
Proton pump
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Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer and reflux esophagitis |
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T21254 |
Vonoprazan Fumarate
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TAK-438,TAK 438,Vonoprazan Fumurate,TAK438 |
Proton pump
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Vonoprazan Fumarate (TAK438) , a novel potassium-competitive acid blocker, inhibits gastric acid secretion. Vonoprazan Fumarate (TAK438) inhibited H+,K+-ATPase activity in porcine gastric microsomes with IC50 value of 19... |
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T25939 |
Pepticinnamin E
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|
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Pepticinnamin E is a naturally occurring bisubstrate farnesyltransferase inhibitor. |
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T27640 |
Itriglumide
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CR-2945,CR2945,CR 2945 |
|
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Itriglumide, a CCK2 receptor antagonist, is used potentially for the treatment of peptic ulcers, dyspepsia, and gastroesophageal reflux disease (GERD). |
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T29015 |
Trithiozine
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Tresanil,Sulmetozine,Tritiozinum,Tritiozine,Tritiozina |
Others
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Trithiozine (Tritiozinum) exhibits antisecretory and antiulcer capacity. Trithiozine can be used for research on the treatment of peptic ulcer disease and hypersecretory disorders. |
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T23667 |
AGN-201904
|
AGN201904,AGN 201904 |
ATPase
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AGN-201904 is a proton pump inhibitor, an omeprazole prodrug, which delays aging and may be used for the prevention and treatment of peptic ulcers. |
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T25737 |
Linetastine
|
TMK 688,TMK-688,TMK688 |
Lipoxygenase
,
LTR
,
Histamine Receptor
|
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Linetastine (TMK-688) is a 5-lipoxygenase inhibitor (5-LOX) that inhibits leukotriene production and antagonizes the effects of histamine.Linetastine is used in studies of asthma, atherosclerosis, and peptic ulcers. |
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T0246L |
Betahistine mesylate
|
Extovyl,Melopat,Meginalisk |
Histamine Receptor
|
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Betahistine mesylate (Extovyl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. |
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T4195 |
Betahistine
|
PT 9 base,Vasomotal,Serc base |
Histamine Receptor
|
|
Betahistine (Vasomotal) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. Betahisti... |
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T10221 |
Abeprazan hydrochloride
|
DWP14012 hydrochloride,Fexuprazan hydrochloride |
Proton pump
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Abeprazan hydrochloride (Fexuprazan hydrochloride) is an effective reversible potassium-competitive acid blocker with oral activity, inhibiting H+, K+ -atPase by competitive binding to potassium ions without acid activat... |
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T0786 |
Clidinium bromide
|
Ro 2-3773 |
AChR
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Clidinium bromide (Ro 2-3773) , a synthetic anticholinergic agent, has been shown in experimental and clinical researchers to have a pronounced antisecretory and antispasmodic effect on the gastrointestinal tract. It can... |
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T34936 |
Tridihexethyl chloride
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Propethonum,Pathilon,Tridihexethyl |
|
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Tridihexethyl is an anticholinergic, antimuscarinic, and antispasmolytic drug, which can be used to treat acquired nystagmus or peptic ulcer disease. |
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T31743 |
Famotine hydrochloride
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Famotine HCl,UK-2054 |
|
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Famotine Hydrochloride is a histamine H2 receptor antagonist that suppresses acid production in the stomach and commonly treats peptic ulcer disease and gastroesophageal reflux disease. |
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T32224 |
Isopropamide
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Priazimide,Dipramide,Piaccamide,Chloroisopropamide,Dipramid |
|
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Isopropamide (R5) is a long-acting anticholinergic drug. It is used to treat peptic ulcers and other gastrointestinal disorders involving excess gastric acid (gastrointestinal acidosis) and hyperactivity. |
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T70127 |
Famotine
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|
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Famotine is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
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T38058 |
Cimetidine sulfoxide
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|
|
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Cimetidine sulfoxide (Cimetidine sulphoxide) is a metabolite of Cimetidine, functioning as a histamine H2-receptor antagonist with potential applications in treating peptic ulcer disease and upper gastrointestinal hemorr... |
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T68725 |
Famotidine propanamide
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|
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Famotidine propanamide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
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T70090 |
Nizatidine amide
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|
|
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Nizatidine amide is a histamine H2 receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
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T2138L |
Oxyphencyclimine
|
Oxiphencycliminum,Antulcus,Zamanil,Manir,Caridan,Naridan |
|
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Oxyphencyclimine is a muscarinic receptor antagonist (MRA) anticholinergic drug used to treat peptic ulcers. |
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T14051 |
5-Hydroxylansoprazole
|
AG1908 |
Proton pump
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5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole, a gastric proton-pump inhibitor that effectively treats various peptic diseases[1][2]. The metabolism of Lansoprazole occurs through CYP2C19, result... |
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T12914 |
Siltenzepine
|
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Others
|
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Siltenzepine is an agent of anti-acid agent,and used in the treatment of peptic ulcers. |
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T68206 |
Arbortristoside A
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|
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Arbortristoside A is an anti-inflammatory and antinociceptive. This activity may be due to the inhibiting effect of prostaglandin, histamine and serotonin. Arbortristoside A has also been shown to act on ulcerations and ... |
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T61228 |
Pirenzepine
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|
|
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Pirenzepine (LS 519 free base) is a selective antagonist of the M1 muscarinic acetylcholine receptor (mAChR). It effectively inhibits gastric acid secretion and reduces muscle spasm, making it a valuable compound for inv... |
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T71980 |
Omeprazole acid
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|
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Omeprazole acid is a medication used in the treatment of gastroesophageal reflux disease, peptic ulcer disease, and Zollinger–Ellison syndrome. It is also used to prevent upper gastrointestinal bleeding in people who are... |
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T71801 |
Arbaprostil
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|
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Arbaprostil is a synthetic prostaglandin E analog that protects gastric mucosa, prevents ulceration, and promotes healing of peptic ulcers. The protective effect is independent of acid inhibition. It is also a potent inh... |
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T19929 |
Ranitidine-S-oxide
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|
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Ranitidine-S-oxide is a metabolite of Ranitidine. It is commonly used in the treatment of peptic ulcer disease, Zollinger–Ellison syndrome，and gastroesophageal reflux disease. |
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T71049 |
Famotidine disulfide
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|
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Famotidine disulfide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
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T71485 |
Famotidine propionic acid
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|
|
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Famotidine propionic acid is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
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T71509 |
Famotidine sulfamoyl propanamide
|
|
|
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Famotidine sulfamoyl propanamide is a histamine H2-receptor antagonist that inhibits stomach acid production. It is commonly used in the treatment of peptic ulcer disease and gastroesophageal reflux disease. |
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T33314 |
Methantheline Bromide
|
Frenogastrico,Dixamone bromide,Banthine,Asabaine,Methanthelinium bromide |
|
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Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancre... |
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T25104 |
Aprofene
|
aprophen,Aprofenum |
|
|
Aprofene (Aprophen) is an antagonist of muscarinic and nicotinic acetylcholine receptors. It may be used in the therapy of peptic ulcers, endarteritis (inflammation of the inner shell of the artery), cholecystitis (infla... |
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T79656 |
Urease-IN-8
|
|
|
|
Urease-IN-8 (Compound 5e) functions as a competitive inhibitor of urease, with an IC50 value of 3.51 μM and a Ki of 3.11 μM. It is applicable for research pertaining to peptic and gastric ulcers [1]. |
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T78237 |
Urease-IN-6
|
|
|
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Urease-IN-6, a potent Urease inhibitor, exhibits an IC50 value of 14.2 μM and is utilized in the research of peptic and gastric ulcers [1]. |
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T70428 |
Nepaprazole sodium
|
|
|
|
Nepaprazole Na is the salt form of Nepaprazole Free Base, also known as TY-11345, is a proton pump inhibitor potentially for treatment of gastric ulcer. TY-11345 potently inhibited H+/K(+)-ATPase activity in isolated ra... |
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T79652 |
Urease-IN-7
|
|
|
|
Urease-IN-7 (Compound 5k) acts as a competitive inhibitor of the enzyme urease, exhibiting an IC50 value of 3.33 μM and a K_i of 3.62 μM. This compound has potential applications in the study of peptic and gastric ulcers... |
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T36714 |
Sucrose octasulfate (potassium salt)
|
|
|
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Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium agains... |
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TMIH-0163 |
Clidinium Bromide-d5
|
|
|
|
Clidinium Bromide-d5 is a deuterated compound of Clidinium Bromide. Clidinium Bromide has a CAS number of 3485-62-9. Clidinium, a synthetic anticholinergic agent, has been shown in experimental and clinical researchers t... |
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T61643 |
Vonoprazan hydrochloride
|
|
|
|
Vonoprazan hydrochloride, a proton pump inhibitor (PPI), effectively acts as a potassium-competitive acid blocker (P-CAB) with potent antisecretory activity. It notably inhibits H+,K+-ATPase activity in porcine gastric m... |
