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T75352 |
Photosensitizer-1
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Photosensitizer-1 (Compound CLB-13) is a photosensitizer [1] . |
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T81483 |
Photosensitizer-2
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Photosensitizer-2 (compound 1), an organic D-π-A sensitizer, exhibits antitumor properties and potent phototoxicity due to an acrylic acid moiety. It demonstrates significant activity against HeLa cells, with IC 50 value... |
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T75353 |
Photosensitizer-1 hydrochloride
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Photosensitizer-1 (Compound CLB-13) hydrochloride is a photosensitizer [1] . |
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T79711 |
Antitumor photosensitizer-4
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Apoptosis
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Antitumor Photosensitizer-4 (compound 10b), a conjugate of dasatinib and imatinib, serves as a potent tyrosine kinase inhibitor (TKI) targeting ABCG2. This photosensitizer (PS) induces apoptosis and reactive oxygen speci... |
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T74601 |
Antitumor photosensitizer-3
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Antitumor Photosensitizer-3 (Compound I), a chlorin derivative, effectively induces apoptosis and necrosis in tumor cells upon exposure to 650 nm laser irradiation. This compound demonstrates reduced skin phototoxicity c... |
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T74392 |
Antimicrobial photosensitizer-1
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Antimicrobial Photosensitizer-1 demonstrates significant potential as an effective agent for treating infections caused by pathogenic microorganisms, with notable antimicrobial efficacy observed in S. aureus-infected mou... |
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T82997 |
Antitumor photosensitizer-2
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Compound 11, also known as Antitumor Photosensitizer-2, is a potent photosensitizer with remarkable photodynamic anti-tumor properties and minimal skin photo-toxicity, representing a promising candidate for photodynamic ... |
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T82998 |
Antitumor photosensitizer-1
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Antitumor Photosensitizer-1 (Compound 8) is a potent photosensitizer with remarkable photodynamic anti-tumor properties and minimal skin photo-toxicity, positioning it as a promising new candidate for photodynamic therap... |
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T3213 |
Hematoporphyrin dihydrochloride
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Hematoporphyrin IX dihydrochloride |
Apoptosis
,
Others
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Endogenous Metabolite
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Hematoporphyrin dihydrochloride (Hematoporphyrin IX dihydrochloride) is a substrate for affinity chromatography of heme-binding proteins. |
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T19525 |
PPA-904
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Others
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PPA-904 is a specific phenothiazine photosensitizer,and used in photodynamic therapy. |
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T15501 |
HPPH
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Photochlor |
Others
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HPPH (Photochlor) (Photochlor) is a second-generation photosensitizer. It is used as photodynamic therapy (PDT) agent. |
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T19637 |
Aluminum phthalocyanine chloride
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Phthalocyanine Chloroaluminum,Chloroaluminum Phthalocyanine |
Others
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Aluminum phthalocyanine chloride (Phthalocyanine Chloroaluminum) is an intensely blue-green-colored aromatic macrocyclic compound that is widely used in dyeing. Aluminum phthalocyanine chloride is a powerful photosensiti... |
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T19525L |
PPA-904 FA
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PPA-904 FA（30189-85-6 Free base） |
Antibiotic
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PPA-904 FA is a cationic photosensitizer with broad-spectrum antimicrobial activity for use in photodynamic studies (PDT) studies of chronic leg ulcers and diabetic foot ulcers. |
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T0830 |
Bithionol
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Actamer |
cAMP
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Parasite
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Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bit... |
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TP1535L |
GPLGIAGQ acetate
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GPLGIAGQ acetate(109053-09-0 Free base) |
MMP
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T72049 |
4-N-Nonyloxyphenol
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4-nonoxyphenol,p-Nonyloxyphenol |
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4-N-Nonyloxyphenol (4-nonoxyphenol), a heterogeneous photosensitizer based on kaolinite nanotubes, is a widely used pesticide and endocrine disruptor for the photodegradation of phenol-based pesticides. |
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T3112 |
Verteporfin
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BPD-MA,CL 318952 |
Apoptosis
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YAP
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VDA
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Autophagy
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Verteporfin (BPD-MA) is a YAP inhibitor that inhibits YAP-TEAD interactions. Verteporfin is also a photosensitizer used in photodynamic therapy. Verteporfin also induces apoptosis and inhibits autophagy. |
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T77681 |
3-Methoxy-9H-Carbazole
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Apoptosis
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3-methoxy-9H-carbazole is a photosensitizer, a natural compound from Klauseneria heptaphylla and Klauseneria indica.3-methoxy-9H-carbazole has anti-breast cancer activity and induces apoptosis. |
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T0402 |
Octocrylene
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Octocrilene |
Others
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Octocrylene (Octocrilene) is used as an ingredient in sunscreens and cosmetics. This organic compound can penetrate into the skin where it acts as a photosensitizer. This results in an increased production of free radica... |
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T8909 |
MFCD01917484
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ETHYL 2-AMINO-4-(4-METHOXYPHENYL)-3-THIOPHENECARBOXYLATE |
Others
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MFCD01917484 (ETHYL 2-AMINO-4-(4-METHOXYPHENYL)-3-THIOPHENECARBOXYLATE) is a derivative of thiophene that possesses a variety of properties, including the ability to act as a ligand, catalyst and photosensitizer. It has ... |
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T36466 |
Chlorin E6
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Ce6,Chlorin e6,CE6 |
Parasite
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Chlorin E6 (CE6) is a second-generation photosensitizer with antitumor activity when used in combination with irradiation. In a mouse model of implanted fibrosarcoma, Chlorin E6 (2.5-10 mg/kg, i.v., 50-200 J/cm2 irradiat... |
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T33958 |
PH 1008
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PH1008,PH-1008 |
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PH 1008 is a porphyrin photosensitizer that may be useful as a diagnostic tool. |
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T16978 |
Talaporfin sodium
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ME2906,NPe6,Mono-L-aspartyl chlorin e6 |
Others
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Talaporfin is a photosensitizer used in photodynamic therapy. |
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T19103 |
2-Selenouracil
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Others
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2-Selenouracil is a specialized photosensitizer for photodynamical therapy. |
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T34738 |
Suftalan Zine
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Suftalan Zine is a potential photosensitizer for the treatment of cancer. |
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T29614 |
ACP-0052
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SL052,SL 052,SL-052,ACP 0052 |
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ACP-0052(SL-052, ACP-SL-052) is a photosensitizer based on hypoclintin that may be used in the treatment of prostate cancer. |
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T39967 |
Br-DAPI
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Br-DAPI is a water-soluble, cell-permeable, DNA-binding photosensitizer. |
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T40435 |
Chlorin e6 trimethyl ester
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Chlorin e6 trimethyl ester, a derivative of methyl pheophorbide-a, is an effective photosensitizer for photodynamic therapy (PDT). |
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T83486 |
[Ru(DIP)2TAP]Cl2
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[Ru(DIP)2TAP]Cl2, a Ruthenium(II) polypyridyl compound, serves as a photosensitizer and is utilized in photodynamic therapy (PDT) research. |
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T38970 |
Hematoporphyrin monomethyl ether
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Hematoporphyrin monomethyl ether (HMME), a second-generation porphyrin-related photosensitizer, is a highly selective and low-toxicity compound known for its singular form and high yield of singlet oxygen. It finds exten... |
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T81028 |
TBTDC
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TBTDC serves as a multifunctional organic photosensitizer exhibiting aggregation-induced emission characteristics, optimal for in vivo bioimaging and photodynamic research applications. |
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T34833 |
TH9402
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TH 9402,TH-9402,Xanthylium |
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TH9402 is a dibrominated rhodamine derivative and potent photosensitizer and useful in photodynamic therapy. TH9402 eradicates multiple myeloma (MM) and BC cell lines, while sparing more than 50% of normal pluripotential... |
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T31793 |
Fimaporfin
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TPCS2a,Disulfonated tetraphenyl chlorin |
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Fimaporfin, also known as TPCS2a, is a potent chlorin-based photosensitizer, Fimaporfin is consisted of a mixture of three isomers A, B and C (25%,50%,25%). Fimaporfin has been developed by di-imide reduction of disulfon... |
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T28782 |
Sinoporphyrin sodium
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sinoporphyrin,DVDMS Free,DVDMS |
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Sinoporphyrin sodium significantly suppressed cell proliferation, promoted early apoptotic response, triggered collapse of F-actin filaments and inhibited cell migration. Sinoporphyrin sodium potentially a treatment for ... |
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T29890 |
AlPcS4
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Aluminum phthalocyanine tetrasulfonate tetrasodium,Chloroaluminum tetrasulfophthalocyanine |
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AlPcS4 , also known as aluminum phthalocyanine tetrasulfonate Chloroaluminum tetrasulfophthalocyanine; or AlS4Pc, AlPcS4(a), is a potent photosensitizer, and is potentially useful in cancer sonodynamic therapy and cancer... |
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T78442 |
TSPP tetrasodium
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TSPP tetrasodium, a photosensitizer, has demonstrated significant efficacy in the in vivo regression of cancer and microbial infections (Ex: 413 nm, Em: 640 nm) [1][2]. |
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T34278 |
Redaporfin
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F 2BMet,F2BMet,F-2BMet,LUZ11,LUZ 11,LUZ-11 |
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Redaporfin, also known as F-2BMet or LUZ-11, is a photosensitizer for Photodynamic Therapy (PDT) of cancer. Redaporfin showed a high efficacy in the treatment of male BALB/c mice with subcutaneously implanted colon (CT26... |
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T29922 |
Aluminum phthalocyanine disulfonate disodium
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AlPcS2,AlPcS(2a),Disulfonated aluminum phthalocyanine,ClAlPcS2. Clalpcs,AlS2Pc |
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Aluminum phthalocyanine disulfonate sodium, also known as AlPcS2 disodium or AlS2Pc or AlPcS(2a), is a potent photosensitizer, and is potentially useful in cancer sonodynamic therapy and cancer photodynamic therapy. Alum... |
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T74335 |
PSDalpha
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PSDalpha, an ERα degrader consisting of a photosensitizer (PS), triphenylamine benzothiadiazole (TB), and 17β-estradiol connected via an acetylene bond, demonstrates superior anti-proliferative effects on MCF-7 cells. It... |
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T75000 |
Mal-Pc
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Reactive Oxygen Species
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Mal-Pc, a phthalocyanine-based molecular photosensitizer featuring maleimides, interacts with GSH to diminish its levels and decrease aggregation, enhancing the ROS (Reactive Oxygen Species)-dependent efficacy of photody... |
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T74922 |
ICy-OH
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ICy-OH, a iodinated photosensitizer, serves as a potent anticancer agent, capable of deep tissue imaging (λ ex =640 nm, λ em =690-740 nm) and selectively triggering cell death in pancreatic cancer cells through the cell ... |
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T80963 |
TPEQM-DMA
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TPEQM-DMA, a NIR-II photosensitizer, selectively accumulates in cancerous mitochondria and demonstrates potent type-I phototherapeutic efficacy that inhibits the growth of cancer cells. This efficacy aids in overcoming t... |
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T78903 |
Antibacterial agent 140 chloride
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Antibacterial agent 140 chloride, a first-of-its-kind Ru-based AIEgen photosensitizer, shows promise in detecting and treating Gram-positive bacteria (G+). It effectively discriminates against and exterminates G+ by inte... |
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T74629 |
Benz-AP
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Benz-AP, a potent photosensitizer, generates singlet oxygen inversely related to Human carboxylesterase 2 (hCES2) activity, showcasing enhanced photocytotoxicity in cancer cells within low hCES2 environments. Moreover, u... |
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T80988 |
Thymolphthalexon tetrasodium
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Thymolphthalexon (tetrasodium) is an organic thioxanthone derivative utilized as a biochemical assay reagent due to its potent antioxidant properties. It plays a significant role in researching free radical response, oxi... |
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T77235 |
Methylene Violet 3RAX
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Methylene Violet 3RAX, a phenazine dye, is utilized for staining cell mitochondria and has the capability to alter DNA's molecular structure, disrupt DNA modules, and promote reactive singlet oxygen generation. It inhibi... |
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T79290 |
SRE-II
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DNA/RNA Synthesis
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SRE-II, an amide derivative, serves as an activatable photosensitizer tailored for photodynamic cancer research, exhibiting diminished fluorescence and photosensitizing properties. Upon carboxylesterase-catalyzed amide b... |
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T75317 |
Vitamin K5
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Vitamin K5 (Synkamin), a photosensitizer and antimicrobial agent, serves as a specific PKM2 inhibitor, demonstrating IC 50 values of 28, 191, and 120 μM against PKM2, PKM1, and PKL, respectively. It induces apoptosis in ... |
