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ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T32046	HBED	CHELII,CHEL II,CHEL-II	Others
	HBED (CHELII) is an iron chelator and can be used in research on the treatment of chronic iron overload and acute iron poisoning.		Others
T1111	Pralidoxime Chloride	2-PAM chloride,2-Pyridinealdoxime methochloride,2-PAM (chloride)	AChE
	Pralidoxime Chloride (2-PAM chloride) is a useful agent in the treatment of organophosphate poisoning. Pralidoxime binds to organophosphate-inactivated acetylcholinesterase, used to combat poisoning by organophosphates o...		AChE
T22321	Edetate calcium disodium	EDTA calcium disodium	Others
	Edetate calcium disodium(EDTA calcium disodium) , a chelating agent, is primarily used for the management of severe lead poisoning.		Others
T19084	1-Naphthyl acetate		AChE
	1-Naphthyl acetate is usually used in a rapid staining method for identification of macrophages. 1-Naphthyl acetate is a potent chromogenic substrate for the detection of erythrocyte acetylcholinesterase (AChE) activity....		AChE
T0765	Fomepizole	Antizol-Vet,4-Methylpyrazole,Antizol	P450 , CAT , AChR
	Fomepizole (4-Methylpyrazole) is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole(4-Methylpyrazole) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that cata...		P450 , CAT , AChR
T16949	Sucrose octaacetate		Others
	Sucrose octaacetate is an acetylated derivative of sucrose. Sucrose octaacetate can be used as food additive and also used as an adhesive and plasticizer. Sucrose octaacetate also used in many pesticides, insecticides, a...		Others
T0006	Methylene Blue trihydrate	Methylthionine chloride,Basic blue 9,Methylene Blue	Guanylate cyclase , Microtubule Associated , NO Synthase , Parasite , Monoamine Oxidase
	Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene Blue trihydrate...
T32074	Hgg 12	Hgg-12,Hgg12
	Hgg 12 is used to treat organophosphorus poisoning.
T20118	L-Penicillamine
	L-Penicillamine is a medication primarily. It is used for the treatment of Wilson's disease. It is also used for people with kidney stones who have high urine cystine levels, rheumatoid arthritis, copper poisoning, and l...
T22404	Pralidoxime Iodide	2-PAM	Others
	Pralidoxime Iodide, also named 2-PAM, is an antidote approved for reactivation of inhibited acetylcholinesterase (AChE) in organophosphate poisoning.		Others
T16372	Obidoxime dichloride		Others
	Obidoxime dichloride, a selective oxime agent, effectively reactivates sarin-inhibited acetylcholinesterase (AChE) and mitigates the acute toxicity associated with sarin exposure. It is also utilized as an antidote for o...		Others
T24538	N-Monoacetylcystine	Parvolex,N-Acetylcystine
	N-Monoacetylcystine is a paracetamol poisoning antidote. It is used in the treatment of influenza A virus pandemic.
T69079	Trimedoxime bromide
	Trimedoxime bromide is a cholinesterase reactivator used as an antidote in alkyl phosphate poisoning.
T62857	K203
	K203 is a potent tabun-inhibited AChE reactivator and is an important antidote to organophosphorus poisoning.
T69193	SN-28049
	SN-28049 SN is a DNA intercalating drug that binds selectively to GC-rich DNA and shows curative activity against the Colon 38 adenocarcinoma in mice. SN 28049 has a complex action that may involve poisoning of topo IIal...
T73060	Pralidoxime
	Pralidoxime is a potent antidote for organophosphate poisoning, effectively reactivating acetylcholinesterase (AChE) that has been inhibited by nerve agents. It achieves this reactivation through a direct nucleophilic at...
T72245	Fomepizole hydrochloride	4-Methylpyrazole hydrochloride
	Fomepizole hydrochloride (4-Methylpyrazole), a potent, orally active inhibitor of cytochrome P450 (CYP2E1) and a competitive inhibitor of alcohol dehydrogenase, prevents the conversion of methanol and ethylene glycol int...
T82551	Dinophysistoxin 1	DTX 1
	Dinophysistoxin 1 (DTX 1, 35-methylokadaic acid), a causative agent of diarrhetic shellfish poisoning, exhibits tumor-promoting activity and also acts as a skin irritant [1].
T35772	Emestrin
	Emestrin is a mycotoxin originally isolated from E. striata that has antimicrobial, immunomodulatory, and cytotoxic activities.1,2,3,4,5 It is active against the fungi C. albicans and C. neoformans, as well as the bacter...

Compounds

HBED

T32046

Synonym: CHELII,CHEL II,CHEL-II

Target: Others

Pralidoxime Chloride

T1111

Synonym: 2-PAM chloride,2-Pyridinealdoxime methochloride,2-PAM (chloride)

Target: AChE

edetate calcium disodium

T22321

Synonym: EDTA calcium disodium

Synonym: Antizol-Vet,4-Methylpyrazole,Antizol

Target: P450, CAT, AChR

Methylene Blue trihydrate

T0006

Synonym: Methylthionine chloride,Basic blue 9,Methylene Blue

Target: Guanylate cyclase, Microtubule Associated, NO Synthase, Parasite, Monoamine Oxidase

Hgg 12

T32074

Synonym: Hgg-12,Hgg12

Synonym: Parvolex,N-Acetylcystine

Fomepizole hydrochloride

T72245

Synonym: 4-Methylpyrazole hydrochloride

カタログ番号	製品名	別名	ターゲット
T7438	3,5-Dimethoxyphenol	Phloroglucinol dimethyl ether	Tyrosinase
	3,5-Dimethoxyphenol (Phloroglucinol dimethyl ether) as a marker of Taxus poisoning, being present in all species of Taxus. It has potent tyrosinase-inhibiting activity.		Tyrosinase
T1396	Bemegride	Bemegrid,3-Ethyl-3-methylglutarimide,Agipnon	GABA Receptor
	Bemegride (3-Ethyl-3-methylglutarimide), a central nervous system stimulant, serves as an antidote for barbiturate poisoning.		GABA Receptor
T3S1888	Deltaline	Deltamine 6-acetate,Eldelin	Others
	Use of Deltaline (Eldelin) as versatile antidotes against poisoning of animals and humans.		Others
T21532	Anisodamine	6-Hydroxyhyoscyamine,6-beta-Hydroxyhyoscyamine	AChR
	Anisodamine (6-beta-Hydroxyhyoscyamine) is an antagonist of muscarinic and nicotinic cholinoceptor with similar affinities at the muscarinic receptor as scopolamine and atropine. Anisodamine improve the microcirculation ...		AChR
TN1749	Huperzine C		Others
	Huperzine has the value as pretreatment of organophosphate poisoning, it can be used as a protective agent against organophosphate intoxication.		Others
T16726	Rebeccamycin		Topoisomerase
	Rebeccamycin is an antitumor antibiotic+ inhibits DNA topoisomerase I. Rebeccamycin appears to exert its primary antineoplastic effect by poisoning topoisomerase I. It also has a negligible effect on protein kinase C and...		Topoisomerase
T36068	Brevetoxin B
	Brevetoxin B is a polyketide neurotoxin produced by Karenia species and other dinoflagellates. It binds to site 5 on the alpha subunit of voltage-gated sodium channels (IC50 = 15 nM) on neurons at the neuromuscular junct...

天然物製品

3,5-Dimethoxyphenol

T7438

Synonym: Phloroglucinol dimethyl ether

Target: Tyrosinase

Bemegride

T1396

Synonym: Bemegrid,3-Ethyl-3-methylglutarimide,Agipnon

Target: GABA Receptor

Deltaline

T3S1888

Synonym: Deltamine 6-acetate,Eldelin

Target: Others

Anisodamine

T21532

Synonym: 6-Hydroxyhyoscyamine,6-beta-Hydroxyhyoscyamine

Target: Topoisomerase

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPH-03546	Enterotoxin type G Protein, S. aureus (strain N315), Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death.
TMPH-03543	Enterotoxin type C-3 Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPH-03545	Enterotoxin type E Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPH-03547	Enterotoxin type G Protein, S. aureus (strain Mu50/ATCC 700699), Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death.
TMPH-03548	Enterotoxin type G Protein, S. aureus (strain N315), Recombinant (His)	Staphylococcus aureus	Yeast
	Staphylococcal enterotoxins cause the intoxication staphylococcal food poisoning syndrome. The illness is characterized by high fever, hypotension, diarrhea, shock, and in some cases death.
TMPH-03541	Enterotoxin type C-2 Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPH-03539	Enterotoxin type B Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	Yeast
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPH-03549	Enterotoxin type H Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	Yeast
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules via their alpha domain, in parti...
TMPH-03544	Enterotoxin type D Protein, S. aureus, Recombinant (His & SUMO)	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPH-03542	Enterotoxin type C-2 Protein, S. aureus, Recombinant	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPH-03540	Enterotoxin type B Protein, S. aureus, Recombinant (GST)	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex a...
TMPH-03538	Enterotoxin type A Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	Baculovirus
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, waves of cellular acti...
TMPH-03537	Enterotoxin type A Protein, S. aureus, Recombinant (His)	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, waves of cellular acti...