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T22408 |
Proflavine
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3,6-Diaminoacridine |
Antibacterial
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Proflavine (3,6-Diaminoacridine) (3,6-Diaminoacridine) is a disinfectant bacteriostatic against many gram-positive bacteria and is a topical antiseptic used mainly in wound dressings. |
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T0438 |
Proflavine Hemisulfate
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3,6-Diaminoacridine hemisulfate,Proflavin hemisulfate |
Others
,
Potassium Channel
,
DNA
,
Thrombin
,
Antibacterial
,
Autophagy
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Proflavine Hemisulfate (3,6-Diaminoacridine hemisulfate) is the hemisulfate salt form of proflavine, an acridine-derived fluorescent contrast and disinfectant agent that can potentially be used for cellular imaging and a... |
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T5585 |
AM-92016 hydrochloride
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Potassium Channel
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AM-92016 is a specific blocker of rectifier potassium current. AM-92016 delays rectifier potassium channel and repolarizes the membrane thereby restricting the duration of the nerve impulse. |
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T22745 |
DPO-1
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Potassium Channel
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DPO-1 is a blocker of IKur ultrarapid delayed rectifier potassium current and KV1.5 channels |
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T27205 |
DPI 201-106
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DPI-201-106 |
Sodium Channel
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DPI-201-106 is a cardioselective inhibitor of the TTX-resistant h1 Na channel inactivation. DPI-201-106 inhibits the L-type calcium current, and inward and delayed rectifier potassium currents. |
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T7505 |
Azimilide Dihydrochloride
|
NE-10064 Dihydrochloride |
Potassium Channel
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Azimilide Dihydrochloride (NE-10064 Dihydrochloride), a novel class III antiarrhythmic agent, blocks both the slowly activating (IKs) and rapidly activating (IKr) components of the delayed rectifier potassium current |
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T3574 |
Sematilide hydrochloride
|
CK-1752A,CK-1752,Sematilide HCl |
Potassium Channel
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Sematilide hydrochloride (CK-1752) is a class III antiarrhythmic. It is a selectively delayed rectifier K+ current (IKr) channel blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, resulting in the ... |
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T6476 |
Dofetilide
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UK 68789,UK-68798,Tikosyn |
Potassium Channel
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Dofetilide (UK 68789) is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ik... |
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T15555 |
IK1 inhibitor PA-6
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Potassium Channel
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IK1 inhibitor PA-6 (PA-6) is a selective and potent inhibitor of IK1 (KIR2.x ion-channel-carried inward rectifier current)(IC50 of 12-15 nM for human and mouse KIR2.x currents). |
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T31011 |
Coralyne chloride
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Topoisomerase
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Coralyne chloride is a protoberberine with strong anticancer activity. It can be used to prepare Coralyne derivatives, a fluorescent DNA-based molecular rectifier built into DNA duplexes through site-specific insertion. ... |
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T22662 |
Chromanol 293B
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Others
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slow delayed rectifier K+ current (IKs) blocker |
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T24948 |
VU625
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VU007625,VU 625,VU 007625,VU-625,VU-007625 |
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VU625 is an effective inhibitor of Aedes aegypti inward rectifier potassium channels. |
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T70194 |
AM92016
|
|
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AM92016 is a specific blocker of the time dependent delayed rectifier potassium current. AM92016 does not show any β-adrenoceptor blocking activity. |
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T5336L |
Zacopride
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Racemic zacopride |
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Zacopride is a selective agonist of inward rectifier potassium current (I K1) channel, inhibiting ventricular arrhythmias without affecting atrial arrhythmias. |
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T14189 |
Almokalant
|
H 234/09 |
Potassium Channel
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Almokalant is a class III antiarrhythmic drug, acts as a potassium channel blocker. And it inhibits a specific component (Ikr) of the time-dependent delayed rectifier K+ current. |
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T15460 |
Halofantrine hydrochloride
|
WR-171669,SKF-102886 |
Others
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Halofantrine hydrochloride is a blocker of delayed rectifier potassium current. Halofantrine hydrochloride also via the inhibition of the human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial agent. |
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T61685 |
Ibutilide
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|
|
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Ibutilide (U70226E free base) is a potent antiarrhythmic compound that extends the action potential duration. It effectively blocks the rapidly activating delayed rectifier potassium current (I Kr ) in AT-1 cells [1]. |
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T80510 |
Tertiapin-RQ
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Potassium Channel
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Tertiapin-RQ, an inward rectifier potassium (K+) channel-blocking peptide, exhibits antidepressant effects [1]. |
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T17240 |
VU041
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|
Others
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VU041 is an inhibitor of Anopheles gambiae and Aedes aegypti inward rectifier potassium 1 channels (IC50: 2.5 μM and 1.7 μM, respectively). VU041 inhibits appreciably is mammalian Kir2.1 (IC50: 12.7 μM) and has less inhi... |
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TP2114 |
Tertiapin-Q
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|
|
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A high affinity blocker for inward-rectifier K+ channels, this compound is a stable derivative of the bee venom toxin tertiapin. Binds to ROMK1 (Kir1.1) and GIRK1/4 (Kir3.1/3.4) channels with high affinity (Ki values are... |
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T36740 |
Guanosine 5’-diphosphate (sodium salt hydrate)
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|
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Guanosine 5’-diphosphate (GDP) is a purine nucleotide and biosynthetic precursor of guanosine 5’-triphosphate .1It has been used to study the conformations of GTPases.2GDP (100 μM) activates sulfonylurea receptor 2B (SUR... |
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T80426 |
Jingzhaotoxin-IX
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Sodium Channel
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Jingzhaotoxin-IX is a C-terminally amidated peptide neurotoxin consisting of 35 amino acid residues. It inhibits both tetrodotoxin-resistant and tetrodotoxin-sensitive isoforms of voltage-gated sodium channels, as well a... |
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T83749 |
Tertiapin LQ TFA
|
TPNLQ |
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Tertiapin LQ, a peptide derivative of honeybee venom peptide tertiapin, acts as an inhibitor of inwardly rectifying potassium (Kir) channels. Specifically, it targets and inhibits heteromultimeric potassium channels, inc... |
