Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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10 mg | 在庫あり | ¥ 7,000 | |||
25 mg | 在庫あり | ¥ 10,000 | |||
50 mg | 在庫あり | ¥ 14,500 | |||
100 mg | 在庫あり | ¥ 21,000 | |||
200 mg | 在庫あり | ¥ 28,500 | |||
500 mg | 在庫あり | ¥ 60,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 9,000 |
説明 | Bexarotene (LGD1069) is a retinoid analogue that is used to treat the skin manifestations of cutaneous T cell lymphoma (CTCL). |
キナーゼ試験 | Biacore studies: Competition assays are performed on a Biacore S51. A Series S Sensor chip CM5 is derivatized for immobilization of a PentaHis antibody for capture of the His-tagged p53. The level of capture is ~ 200 response units (1 response unit corresponds to 1 pg of protein per mm 2). The concentration of MDM2 protein is kept constant at 300 nM. Test compounds are dissolved in DMSO at 10 mM and further diluted to make a concentration series of inhibitor in each MDM2 test sample. The assays are run at 25 °C in running buffer (10 mM Hepes, 0.15 M NaCl, 2% DMSO). MDM2-p53 binding in the presence of inhibitor is calculated as a percentage of binding in the absence of inhibitor and IC50 is calculated using Microsoft Excel |
別名 | Ro 26-4455, Targretin, LGD1069 |
分子量 | 348.48 |
分子式 | C24H28O2 |
CAS No. | 153559-49-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL (57.39 mM), Sonication is recommended.
Ethanol: 7 mg/mL (20 mM)), Heating is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Bexarotene 153559-49-0 Autophagy Metabolism Retinoid Receptor Ro 26-4455 cutaneous Targretin lymphoma selective,?retinoid inhibit Retinoic acid receptors antineoplastic LGD 1069 LGD-1069 T-cell LGD1069 RAR/RXR Inhibitor anti-cancer Retinoid X receptors RXR inhibitor