T15244 |
Ertugliflozin L-pyroglutamic acid
|
1210344-83-4
|
98%
|
|
Ertugliflozin L-pyroglutamic acid (PF-04971729 L-pyroglutamic acid) is a selective and orally active hSGLT2 inhibitor with an IC50 of 0.877 nM. Ertugliflozin L-p...
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T68174 |
Sergliflozin A
|
360775-96-8
|
98%
|
|
Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia.
|
T7217 |
Bexagliflozin
|
1118567-05-7
|
|
|
Bexagliflozin (EGT1442) is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 5.6 μM and 2 nM for human SGLT1 and SGLT2, r...
|
T28757 |
Sergliflozin etabonate
|
408504-26-7
|
95.59%
|
|
Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity.
|
T67849 |
O-Desethyl Dapagliflozin
|
864070-37-1
|
97.09%
|
|
O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.
|
T38843 |
Enavogliflozin
|
1415472-28-4
|
97.81%
|
|
Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.
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T16083 |
Mizagliflozin
|
666843-10-3
|
98.66%
|
|
Mizagliflozin (GSK-1614235 free base) is a sodium-glucose transporter inhibitor( Ki of 27 nM for human SGLT1). Mizagliflozin displays 303-fold selectivity over S...
|
T5016 |
Tofogliflozin (hydrate)
|
1201913-82-7
|
98.78%
|
|
Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2(IC50 of 2.9 nM and Ki values of 2.9 nM, 14.9 nM, and 6.4 nM for human,...
|
T15656 |
KGA-2727
|
666842-36-0
|
98.95%
|
|
KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2/K...
|
T34286 |
Remogliflozin etabonate
|
442201-24-3
|
99%
|
|
Remogliflozin etabonate (GSK189075A) is a prodrug of regaliflozin and an inhibitor SGLT2 with Ki values of 1.95, 2.14, 8.57, and 43.1μM for hSGLT2, rSGLT2, rSGLT...
|
T4999 |
Ertugliflozin
|
1210344-57-2
|
99.27%
|
|
PF-04971729 (Ertugliflozin (PF-04971729)) is a potent and selective inhibitor of the sodium-dependent glucose cotransporter 2 (SGLT2).
|
T3547 |
Sotagliflozin
|
1018899-04-1
|
99.37%
|
|
Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potential antihyperglyce...
|
T4460 |
Dapagliflozin ((2S)-1,2-propanediol, hydrate)
|
960404-48-2
|
99.39%
|
|
Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-t...
|
T9590 |
T-1095
|
209746-59-8
|
99.56%
|
|
T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).
|
T2922 |
Phlorizin
|
60-81-1
|
99.68%
|
|
Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .
|
T2389 |
Dapagliflozin
|
461432-26-8
|
99.74%
|
|
Dapagliflozin (BMS-512148) is a selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity.
|
T2924 |
Phloretin
|
60-82-2
|
99.76%
|
|
Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a ...
|
T1782 |
Canagliflozin
|
842133-18-0
|
99.76%
|
|
Canagliflozin (JNJ 28431754AAA), a sodium-glucose transporter 2( SGLT2) and P-Glycoprotein inhibitor, is used in type 2 diabetes.
|
TN1856 |
Leachianone A
|
97938-31-3
|
99.79%
|
|
Leachianone A (Isokurarinone) is a potential antitoxic agent, it shows inhibitory effects on cadmium- Induced cytotoxicity.
|
T1766 |
Empagliflozin
|
864070-44-0
|
99.89%
|
|
Empagliflozin (BI 10773) is an SGLT-2 inhibitor (IC50=3.1 nM) that is potent and selective, with more than 300-fold selectivity for SGLT-1/4/5/6. Empagliflozin i...
|