Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
500 mg | 在庫あり | ¥ 10,500 | |||
1 g | 在庫あり | ¥ 13,000 | |||
5 g | 在庫あり | ¥ 45,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 12,000 |
説明 | Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) . |
ターゲット&IC50 | SGLT1 (human):300 nM(Ki), SGLT2 (human):39 nM(Ki) |
In vivo | In the treatment of diabetes, obesity, and stress-induced hyperglycemia, Phlorizin exerts its therapeutic effects by inhibiting the sodium-glucose cotransporters located in the proximal renal tubules and the intestinal mucosa. This inhibition results in renal glucosuria and impedes the absorption of glucose in the intestines. |
植物由来 |
別名 | Floridzin, NSC 2833, Phloridzin |
分子量 | 436.41 |
分子式 | C21H24O10 |
CAS No. | 60-81-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 43.6 mg/mL (100 mM)
DMSO: 60 mg/mL (137.49 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Phlorizin 60-81-1 GPCR/G Protein Membrane transporter/Ion channel SGLT ATPase Floridzin Na+/K+ ATPase Sodium potassium pump Inhibitor NSC-2833 inhibit NSC2833 NSC 2833 Sodium-dependent glucose cotransporters Phloridzin inhibitor