Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). It is in development for the treatment of type 2 diabetes mellitus (T2DM). It inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 10,000 | |||
10 mg | 在庫あり | ¥ 14,000 | |||
25 mg | 在庫あり | ¥ 17,000 | |||
50 mg | 在庫あり | ¥ 21,500 | |||
100 mg | 在庫あり | ¥ 27,000 | |||
500 mg | 在庫あり | ¥ 65,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,000 |
説明 | Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-transporter type 2 (SGLT2). It is in development for the treatment of type 2 diabetes mellitus (T2DM). It inhibits subtype 2 of the sodium-glucose transport proteins (SGLT2), which is responsible for at least 90% of the glucose reabsorption in the kidney. |
ターゲット&IC50 | SGLT2: |
In vitro | Dapagliflozin (2S)-1,2-propanediol, hydrate is the S-enantiomer of Dapagliflozin 1,2-propanediol, hydrate. Dapagliflozin inhibits sodium/glucose cotransporter 2 (SGLT2), which results in excretion of glucose into the urine. |
別名 | BMS-512148 (2S)-1,2-propanediol, hydrate, Dapagliflozin propanediol monohydrate |
分子量 | 502.98 |
分子式 | C24H35ClO9 |
CAS No. | 960404-48-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (99.41 mM)
You can also refer to dose conversion for different animals. 詳細
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Dapagliflozin ((2S)-1,2-propanediol, hydrate) 960404-48-2 GPCR/G Protein SGLT Dapagliflozin ((2S) 1,2 propanediol, hydrate) inhibit BMS-512148 (2S)-1,2-propanediol, hydrate Inhibitor Dapagliflozin propanediol Monohydrate Dapagliflozin propanediol Sodium-dependent glucose cotransporters Dapagliflozin propanediol monohydrate BMS-512148 1,2-propanediol, Hydrate Dapagliflozin ((2S)1,2propanediol, hydrate) Dapagliflozin (1,2-propanediol, hydrate) inhibitor