Powder: -20°C for 3 years | In solvent: -80°C for 1 year
1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for native T-currents[1]. Additionally, 1-Octanol is recognized for its potential as a biofuel, possessing diesel-like properties[2].
説明 | 1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for native T-currents[1]. Additionally, 1-Octanol is recognized for its potential as a biofuel, possessing diesel-like properties[2]. |
ターゲット&IC50 | Ca2+ channel, T-type:4 μM |
In vitro | 1-octanol inhibits native T-currents at subanesthetic concentrations with an IC50 of approximately 4 μM. In contrast, 1-octanol is up to 30-fold less potent in inhibiting recombinant CaV3.3 T-channels heterologously expressed in human embryonic kidney cells[1]. |
別名 | Octanol |
分子量 | 130.23 |
分子式 | C8H18O |
CAS No. | 111-87-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (383.94 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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1-Octanol 111-87-5 Membrane transporter/Ion channel Metabolism Endogenous Metabolite Calcium Channel inhibit fatty 1Octanol 1 Octanol diesel-like alcohol biofuel Ca2+ channels T-currents Ca channels T-channels Inhibitor Octanol saturated inhibitor