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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T13896 | Soya fatty acids | Others | |
Soya fatty acids is a class of polyunsaturated fatty acids isolated from soybean. | |||
T8642 | 4-CMTB | GPR | |
4-CMTB is a selective agonist of FFA2 and GPR43.It also is a positive allosteric modulator (pEC50=6.38). | |||
T6043 | PF-3845 | FAAH , Autophagy | |
PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2. | |||
T11557 | FASN-IN-3 | Fatty Acid Synthase | |
FASN-IN-3 is an inhibitor of fatty acid synthase (FASN). | |||
T7947 | FT113 | Fatty Acid Synthase | |
FT113 is a novel potent inhibitor of fatty acid synthase (fasn, IC50 : 213 nM),and exhibits anti-cancer activity | |||
T0686 | Orlistat | Ro-18-0647,Tetrahydrolipstatin | Apoptosis , Others , Fatty Acid Synthase |
Orlistat (Tetrahydrolipstatin) is an Intestinal Lipase Inhibitor. The mechanism of action of orlistat is as a Lipase Inhibitor. | |||
T7796 | TUG-1375 | GPR | |
TUG-1375 is an Agonist of Thiazolidine Free Fatty Acid Receptor 2 | |||
T28353 | PDP-EA | FAAH | |
PDP-EA is an activator of fatty acid amide hydrolase(FAAH) and enhances the amidohydrolase activity of FAAH. | |||
T17181 | TVB-3664 | Fatty Acid Synthase | |
TVB-3664 significantly decreases tubulin palmitoylation and mRNA expression. TVB-3664 is a reversible and highly bioavailable fatty acid synthase inhibitor (IC50: 18 nM and 12 nM for human and mouse cell palmitate synthe... | |||
T15810 | LY2922470 | GPR | |
LY2922470 reduces glucose levels along with significant enhancements in insulin and GLP-1, which is the potential for the treatment of type 2 diabetes mellitus (T2DM). LY2922470 is an effective, selective, and orally ava... | |||
T2684 | JNJ-1661010 | JNJ1661010,Takeda-25,JNJ 1661010 | FAAH |
JNJ-1661010 (Takeda-25) is an effective and specific FAAH inhibitor (IC50: 10/ 12 nM for rat/human), shows >100-fold selectivity for FAAH-1 than FAAH-2. | |||
T17180 | TVB-3166 | Apoptosis , Others , Fatty Acid Synthase | |
TVB-3166 induces apoptosis and inhibits in-vivo xenograft tumor growth. TVB-3166 is a reversible and selective fatty acid synthase inhibitor (IC50s: 42 nM and 81 nM for biochemical FASN and cellular palmitate synthesis,... | |||
T9967 | MAGL-IN-5 | Lipid | |
MAGL-IN-5 is a non-selective lipase inhibitor. | |||
T3215 | JNJ-42165279 | JNJ42165279 | FAAH , Autophagy |
JNJ-42165279 covalently inactivates the FAAH enzyme but is highly selective with regard to other enzymes, ion channels, transporters, and receptors. JNJ-42165279 (10 μM) exhibits high selectivity against a panel of 50 re... | |||
T12580 | PTUPB | COX , Epoxide Hydrolase | |
PTUPB is a potent and dual inhibitor of sEH and COX-2 enzymes(IC50 of 0.9 nM and 1.26 μM, respectively). | |||
T21729 | (±)-Lisofylline | Others | |
(±)-Lisofylline is an enantiomer-specific, alkyl-substituted methylxanthine, which has specific and potent activity in down-regulating leukocyte activation. (±)-Lisofylline is an anti-inflammatory agent. | |||
T7798 | FGH10019 | FGH-10019 | NPC1L1 , Fatty Acid Synthase |
FGH10019 is a novel inhibitor of sterol regulatory element-binding protein (SREBP) ( IC50 :1 μM). | |||
T8646 | URB937 | FAAH | |
URB937 is an inhibitor of FAAH and increases anandamide levels(IC50 : 26.8 nM). | |||
T7688 | 4-Nonylphenylboronic acid | FAAH | |
4-Nonylphenylboronic acid is a inhibitor of FAAH. | |||
T11458 | GPR40/FFAR1 modulator 1 | GPR | |
GPR40/FFAR1 modulator 1 is a Gq-coupled free fatty acid receptor 1 (GPR40/FFAR1) agonist and allosteric modulator. | |||
T3433 | TUG-891 | TUG 891,TUG891 | GPR |
TUG-891 is a G protein-coupled receptor (GPCR) expressed in intestine, adipocytes, and pro-inflammatory macrophages that is activated by long chain free fatty acids. | |||
T2601 | Vidofludimus | SC12267,4sc-101 | Dehydrogenase , DNA/RNA Synthesis , Interleukin |
Vidofludimus (SC12267) (4SC-101, SC12267) is a novel small molecule inhibitor of dihydroorotate dehydrogenase (DHODH). | |||
T29350 | 2-Hexyldecanoic acid | Pentadecane-7-carboxylic Acid,Isopalmitic Acid,7-Pentadecanecarboxylic acid,C16 Guerbet fatty acid,2-Hexyldecansaeure | |
2-Hexyldecanoic acid is a biochemical. | |||
T4323 | PF-04457845 | PF04457845,PF 04457845 | FAAH , Autophagy |
PF-04457845 is a greatly and effctive FAAH inhibitor, and for hFAAH(IC50=7.2±0.63 nM) and rFAAH(IC50=7.4±0.62 nM). | |||
T2351 | Fasiglifam | TAK875 | GPR |
Fasiglifam (TAK875) is a potent, selective and orally bioavailable GPR40 agonist. | |||
T9808 | Tetradecylthioacetic acid | PPAR | |
Tetradecylthioacetic acid is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxidation and increases its biological activity, including acti... | |||
T7092 | NADPH tetrasodium salt | Others , Ferroptosis , Endogenous Metabolite | |
NADPH tetrasodium salt is the reduced form of the electron acceptor nicotinamide adenine dinucleotide phosphate, which acts as an electron donor in a variety of biological reactions. NADPH tetrasodium salt is also an end... | |||
T2338 | JZL195 | FAAH , Lipase , Autophagy | |
JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor. | |||
T4534 | BMS-309403 | FABP | |
BMS-309403 is an effective, selective and cell-permeable inhibitor of fatty acid binding protein 4 (FABP4) with a Ki of less than 2 nM. | |||
T11267 | FASN-IN-1 | TVB-2460 | Fatty Acid Synthase |
FASN-in-1 is an effective, specific inhibitor of fatty acid synthase (FASN), a compound specifically designed to target and inhibit the activity of the enzyme involved in fatty acid synthesis, potentially disrupting fatt... | |||
T8927 | WWL 154 | WWL-154 | FAAH |
WWL 154 is an serine hydrolase (SH) and fatty acid amide hydrolase FAAH-4 inhibitor. | |||
T9722 | YTX-465 | Stearoyl-CoA Desaturase (SCD) | |
YTX-465 is an inhibitor of both stearoyl-CoA desaturase(IC50s = 39 nM) and Ole1 (IC50s = 30.4 μM). | |||
T9266 | Fatostatin | Lipid , Fatty Acid Synthase | |
Fatostatin is a specific inhibitor of SREBP activation, it impairs the activation of SREBP-1 and SREBP-2. Fatostatin binds to SCAP (SREBP cleavage-activating protein), and inhibits the ER-Golgi translocation of SREBPs. | |||
T7482 | 3-chloro-5-hydroxybenzoic Acid | GPR | |
3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 : 16 μM) | |||
TQ0020 | AMG 837 calcium hydrate | GPR | |
AMG 837 calcium hydrate is a potent GPR40 agonist with an EC50 of 13 nM. AMG 837 calcium hydrate also shows highly selective over GPR41, GPR43, and GPR120 (EC50 > 10,000 nM). | |||
T15802 | LY2183240 | FAAH , Autophagy | |
LY2183240 inhibits fatty acid amide hydrolase (FAAH) activity (IC50 = 12.4 nM). LY2183240 is a novel and highly effective blocker of anandamide uptake (IC50 = 270 pM). | |||
T7127 | DC260126 | Apoptosis , GPR | |
DC260126 is a small-molecule antagonist of FFA1 (GPR40) | |||
T1325 | Carprofen | Ridamyl,Imadyl,Rimadyl | FAAH , COX , Autophagy |
Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities. | |||
T3354 | BIA 10-2474 | BIA10-2474 | FAAH , Autophagy |
BIA 10-2474 is a long-acting reversible inhibitor of fatty acid amide hydrolase (FAAH) that increases levels of the neurotransmitter anandamide in the central nervous system and in peripheral tissues (that is, the rest o... | |||
T22027 | AH-7614 | AH 7614 | GPR |
AH-7614 (AH 7614) is a selective and potent free fatty acid receptor 4 (FFA4/GPR120) antagonist. | |||
T4312 | GPR120 Agonist 2 | GPR120 receptor agonist | GPR |
GPR120 Agonist 2 is a potent and selective GPR120 receptor agonist. | |||
T15413 | GPR120 Agonist 3 | GPR120-IN-1 | GPR |
GPR120 Agonist 3 (GPR120-IN-1) is a selective agonist of Gpr120 ( logEC50: -7.62). | |||
T7832 | Ibrolipim | NO-1886 | LPL Receptor |
Ibrolipim (NO-1886) attenuates high glucose-induced endothelial dysfunction in cultured human umbilical vein endothelial cells via PI3K/Akt pathway. | |||
T22967 | MEDICA16 | MEDICA 16 | GPR , Others , ATP Citrate Lyase |
Free fatty acid 1 (FFA1/GPR40) receptor agonist | |||
T12437 | PF429242 dihydrochloride | S1P Receptor | |
PF429242 dihydrochloride is a reversible and competitive inhibitor of S1P (IC50 of 175 nM). | |||
T1889 | CP-640186 | CP 640186 | Acetyl-CoA Carboxylase |
CP-640186 is an isozyme-nonselective Acetyl-CoA carboxylase (ACCase) inhibitor. The IC50s of CP-640186(CP 640186) is 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively. | |||
T36841 | IPI-9119 | Fatty Acid Synthase | |
IPI-9119 is an orally active, selective and irreversible FASN inhibitor (IC50 = 0.3 nM). | |||
T11256 | FAAH inhibitor 1 | Benzothiazole analog 3 | FAAH |
FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM. | |||
T12306 | OMDM-5 | Cannabinoid Receptor , Endogenous Metabolite , TRP/TRPV Channel | |
OMDM-5 is a selective anandamide cellular uptake (ACU)inhibitor(Ki of 4.8 μM). | |||
T3171 | GSK137647A | GSK 137647 | GPR |
GSK137647A (GSK 137647) is a selective FFA4 agonist. |
カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
TN4662 | Nonanal | Others | |
Nonanal is a growth factor for wood-rotting fungi. Nonanal is a potential attractant for the pine shoot beetle. | |||
TQ0260 | Cerulenin | Antibiotic , Antifungal , Fatty Acid Synthase | |
Cerulenin is a natural inhibitor of fatty acid synthase (FAS). It is produced by the fungus Cephalosporium caeruleus. | |||
T8276 | Methyl palmitoleate | Others | |
Palmitoleic acid methyl ester is an ester version of palmitoleic acid, an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue. | |||
T2824 | Pedunculoside | Others , Fatty Acid Synthase | |
Pedunculoside is extracted from Ilex rotunda Thunb. | |||
T8192 | Pentacosanoic acid | Others , Endogenous Metabolite | |
Pentacosanoic acid, belongs to the class of organic compounds known as very long-chain fatty acids. | |||
T14862 | Caprylic/Capric Triglyceride | Others | |
Caprylic/Capric Triglyceride, a compound consisting of triglycerides and esters derived from fractionated vegetable oil, and fatty acids from coconut and palm kernel oils, serves as a food additive and is utilized in cos... | |||
T13719 | Hexadecanal | Palmitaldehyde | Endogenous Metabolite |
Hexadecanal (Palmitaldehyde) is a free fatty aldehyde present in animals. | |||
T7529 | Yamogenin | Others | |
Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek. | |||
TN6953 | Lignoceric Acid | tetracosanoic acid | Endogenous Metabolite |
Lignoceric Acid (tetracosanoic acid) is a 24-carbon saturated (24:0) fatty acid and a by-product of lignin production, which is synthesized in the developing brain. | |||
T5567 | Tetradecanedioic acid | Tetradecanedicarboxylate | Others , Endogenous Metabolite |
Tetradecanedioic acid (Tetradecanedicarboxylate) is a long-chain fatty acid that is a type of endogenous metabolite. It can serve as a candidate biomarker for drug-drug interactions mediated by organic anion transporting... | |||
T2919 | Sesamin | Fagarol,Fsesamin | Others |
Sesamin (Fsesamin) is a lignan extracted from Sesamum indicum L. | |||
T10857 | Coenzyme A | Endogenous Metabolite | |
Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine. | |||
T7967 | Methyl behenate | Others | |
Methyl behenate is a natural compound, is an ester form of docosanoic acid . | |||
T9512 | Linoleyl alcohol | CIS,CIS-9,12-OCTADECADIENOL | Others |
Linoleyl alcohol (CIS,CIS-9,12-OCTADECADIENOL), fatty alcohol, is a structural analog of Linoleic acid with no a-carboxyl group[1]. | |||
T5S0246 | Pseudoprotodioscin | Others , Fatty Acid Synthase | |
1. Pseudoprotodioscin has moderate cytotoxicity. | |||
T3324 | Lycorine | Galanthidine,Narcissine,Amarylline,Belamarine,Licorine | Apoptosis , Virus Protease , Antibacterial , AChR , Fatty Acid Synthase |
Lycorine (Narcissine) inhibits protein synthesis and may inhibit ascorbic acid biosynthesis, although studies on the latter are controversial and inconclusive. | |||
TJS0387 | Desoxyrhaponticin | Deoxyrhapontin,Deoxyrhaponticin | Apoptosis , Fatty Acid Synthase |
1. Desoxyrhaponticin (Deoxyrhaponticin) is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least... | |||
T2859 | Biochanin A | 4-Methylgenistein,Olmelin | EGFR , FAAH , Autophagy |
Biochanin A (4-Methylgenistein) is an isoflavone derivative isolated from red clover Trifolium pratense with anticarcinogenic properties. Biochanin A is a naturally occurring fatty acid amide hydrolase (FAAH) inhibitor. | |||
T11590 | (-)-Hydroxycitric acid | Garcinia acid | ATP Citrate Lyase |
(-)-Hydroxycitric acid (Garcinia acid) (Garcinia acid) is the principal acid of fruit rinds of Garcinia cambogia. It is a potent and competitive inhibitor of ATP citrate lyase. (-)-Hydroxycitric acid suppresses fatty aci... | |||
T7647 | Eicosadienoic acid | Endogenous Metabolite | |
Eicosadienoic acid is a rare, natural n-6 polyunsaturated fatty acid found mainly in animal tissues. | |||
T5368 | Eicosapentaenoic Acid | Histone Demethylase , Others , Endogenous Metabolite | |
Eicosapentaenoic Acid (EPA) is a ω-3 fatty acid abundantly available in marine organisms. | |||
TN1965 | N-Benzyllinolenamide | N-Benzyllinolenamide | FAAH , Autophagy |
N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM). | |||
T0846 | L-Carnitine | L(-)-Carnitine,Levocarnitine | Endogenous Metabolite , Fatty Acid Synthase |
L-Carnitine (L(-)-Carnitine) is an amino acid derivative. L-Carnitine facilitates long-chain fatty acid entry into mitochondria, delivering substrate for oxidation and subsequent energy production. Fatty acids are utiliz... | |||
T10024 | 1-Octanol | Octanol | Calcium Channel , Endogenous Metabolite |
1-Octanol, a saturated fatty alcohol, functions as an inhibitor of T-type calcium channels (T-channels), showing an inhibitory concentration (IC50) of 4 μM for native T-currents[1]. Additionally, 1-Octanol is recognized ... | |||
T7464 | 3,3-Dimethylglutaric acid | 3,3-Dimethylpentanedioate | Others , Endogenous Metabolite |
3,3-Dimethylglutaric acid (3,3-Dimethylpentanedioate) is a compound found in human urine. | |||
T12139 | N-(3-Methoxybenzyl)Palmitamide | FAAH | |
N-(3-Methoxybenzyl)Palmitamide is a promising FAAH inhibitor, treatment of pain, inflammation and CNS degenerative disorders. | |||
T3121 | Betulin | Trochol,betulinic alcohol,betuline,betulinol,Betulol | Apoptosis , Endogenous Metabolite , Lipid , Fatty Acid Synthase |
Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene. It is commonly isolated from the bark of birch trees where it forms up to 30% of the dry weight of the extractive and is fo... | |||
T19180 | Adrenic Acid | cis-7,10,13,16-Docosatetraenoic acid | Endogenous Metabolite |
Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) is a member of the class of compounds known as very-long-chain fatty acids. Adrenic Acid can be found in blood and in human myelin tissue. | |||
T3919 | Ginsenoside Rb2 | Ginsenoside C | GPR , Others , Influenza Virus , Endogenous Metabolite |
Ginsenoside Rb2 (Ginsenoside C) found in species of Panax, upregulating GPR120 gene expression. | |||
T3950 | Tridecanoic acid | n-Tridecoic Acid,n-Tridecanoic Acid,Tridecylic Acid | Others , Endogenous Metabolite , Antibacterial |
Tridecanoic acid (Tridecylic Acid) is a 13-carbon saturated fatty acid found in dairy products and also as a product of anaerobic biodegradation of n-hexadecane. It has been identified as a substrate of phospholipase A2. | |||
T3S2105 | N-Benzylpalmitamide | Macamide 1,N-Benzylhexadecanamide | Others , FAAH , Autophagy |
N-Benzylpalmitamide (Macamide 1) inhibits fatty acid amide hydrolase (FAAH) in a time-dependent manner and could potentially offer a good alternative for the treatment of pain, inflammation and CNS degenerative disorders... | |||
T3322 | Trans-Chalcone | Chalcone,Cinnamophenone,Chalkone | Apoptosis , Others , Antifungal , Fatty Acid Synthase |
trans-Chalcone (Chalkone) is an aromatic ketone that forms the central core for a variety of important biological compounds, which are known collectively as chalcones. | |||
T19676 | Tributyrin | NSC661583,NSC 661583,NSC-661583 | Apoptosis |
Tributyrin (Glyceryl tributyrate), a neutral short-chain fatty acid triglyceride, is a stable and rapidly absorbed prodrug of Butyric Acid. Tributyrin diffuses through biological membranes and is metabolized by intracell... | |||
T1286 | Vincamine | Angiopac,Oxybral,Devincan,Novicet,Equipur,Perval | GPR , Others |
Vincamine (Perval) is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cerebrovascular disorders. | |||
T4P2931 | Linoleic acid | 9,12-octadecadienoic acid,acidelinoleique,9,12-Linoleic acid | Others , Endogenous Metabolite |
Linoleic acid (9,12-octadecadienoic acid) is an essential fatty acid. Prostaglandin precursor. | |||
T4S1173 | Agrimol B | Sirtuin , PPAR | |
1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb. | |||
T3P2904 | α-Linolenic acid | Alpha-Linolenic Acid,Linolenic acid | Akt , PI3K |
α-Linolenic acid (Alpha-Linolenic Acid) is an essential fatty acid belonging to the omega-3 fatty acids group. It is highly concentrated in certain plant oils and has been reported to inhibit the synthesis of prostagland... | |||
T4859 | 1-Monomyristin | rac-Glycerol 1-myristate,Glyceryl myristate,Monomyristin,2,3-Dihydroxypropyl tetradecanoate | Others , FAAH , Endogenous Metabolite , Antibacterial , Autophagy , Antifungal |
1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) , a 1-monoglyceride of myristic acid, has antibacterial activity against several Gram-positive bacterial strains. 1-Myristoyl-rac-glycerol is used in colloidal chemistr... | |||
TQ0251 | (Z)-2-decenoic acid | (Z)-dec-2-enoic acid,cis-2-Decenoic acid,cis-dec-2-enoic acid | Others |
(Z)-2-decenoic acid (cis-dec-2-enoic acid) is an unsaturated short-chain fatty acid secreted by Pseudomonas aeruginosa. It can induce a dispersion response in biofilms formed by gram-negative and gram-positive bacteria. ... | |||
T4S1421 | Praeruptorin B | Praeruptorin D | NPC1L1 , Fatty Acid Synthase |
Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs). It can also significantly up-regulate CYP3A4 expression and activity via the PXR-mediated pathway. | |||
T18927 | Br-Mmc | 4-Bromomethyl-7-methoxycoumarin | Others |
Br-Mmc (4-Bromomethyl-7-methoxycoumarin) is used as a new fluorescence label for fatty acids. It is used for the determination of fatty acids by HPLC or TLC. | |||
T5223 | Heneicosanoic acid | Heneicosylic Acid,C21:0 | Others , Endogenous Metabolite |
Heneicosanoic acid (C21:0) (HEA) is a fatty acid found in human milk fat. HEA is also a part of the phospholipids of the articular cartilage boundary lubricant. HEA is a constituent of red blood cell fatty acids. | |||
T9514 | 1-Dodecanol | Endogenous Metabolite | |
1-Dodecanol is an endogenous metabolite and a saturated fatty alcohol from coconut oil fatty acids. It has a floral odor and is used in detergents, Lepidopteran pheromone/sex attractant, lubricating oils, pesticides and ... | |||
T4944 | Nervonic acid | cis-15-Tetracosenoic acid,Selacholeic acid | Endogenous Metabolite |
Nervonic acid (Selacholeic acid) is a long chain unsaturated fatty acid that is enriched in sphingomyelin. It consists of choline, sphingosine, phosphoric acid, and fatty acid. Nervonic acid may enhance the brain functio... | |||
T8032 | 4-Pentenoic acid | Others , Endogenous Metabolite | |
4-Pentenoic acid, also known as allyl acetic acid or 4-pentenate, belongs to the class of organic compounds known as straight chain fatty acids. These are fatty acids with a straight aliphatic chain. 4-Pentenoic acid is ... | |||
T31708 | Ethyl caprate | Decanoic acid, ethyl ester,Ethyl decylate,Ethyl decanoate,Ethyl caprinate,Capric acid ethyl ester | |
Ethyl caprate, also known as Ethyl decanoate, is a fatty acid ester formed from capric acid and ethanol. This ester is a frequent product of fermentation during winemaking, especially at temperatures above 15 °C. | |||
T8049 | Pentadecanoic acid | Others , Endogenous Metabolite | |
Pentadecylic acid is a saturated fatty acid. | |||
T3949 | Myristic acid | Crodacid,Tetradecanoic acid,n-Tetradecanoic acid | Others , Endogenous Metabolite |
Myristic acid (Crodacid) , a 14 carbon saturated fatty acid, is a rare molecule in cells and is a substrate of some fatty acid desaturases. This compound has the ability to acylate proteins by covalently binding to the N... | |||
T5369 | Docosahexaenoic Acid | Cervonic acid,DHA | Others , Endogenous Metabolite |
Docosahexaenoic Acid (DHA) is an essential fatty acid and an omega-3 fatty acid abundant in brain and retina. | |||
T5246 | Trans-2-butene-1,4-dicarboxylic acid | trans-2-Butene-1,4-dicarboxylic Acid,3-Hexenedioic Acid,trans-3-Hexenedioic Acid,β-Hydromuconic Acid | Others , Endogenous Metabolite |
Trans-2-butene-1,4-dicarboxylic acid (3-Hexenedioic Acid) is a normal human unsaturated dicarboxylic acid metabolite with increased excretion in patients with Dicarboxylic aciduria caused by fatty acid metabolism disorde... | |||
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カタログ番号 | 製品名 | Species | Expression System |
---|---|---|---|
TMPY-06686 | FASN Protein, Mouse, Recombinant (His) | Mouse | E. coli |
FASN Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.23 kDa and the accession number is P19096. | |||
TMPJ-01073 | FABP5 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty acid-binding protein 5 (FABP5) is a cytoplasm protein that belongs to the fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytopl... | |||
TMPJ-00785 | FABP3 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is in... | |||
TMPY-06683 | FASN Protein, Human, Recombinant (His) | Human | E. coli |
FASN Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35.26 kDa and the accession number is P49327. | |||
TMPH-00933 | ADTRP Protein, Human, Recombinant (His & Myc) | Human | E. coli |
ADTRP Protein, Human, Recombinant (His & Myc) is expressed in in vitro E. coli expression system. | |||
TMPJ-00671 | FABP7 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty Acid-Binding Protein 7 (FABP7) is a cytoplasm protein that belongs to the Fatty-acid Binding Protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytopl... | |||
TMPY-02051 | FABP2 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty acid binding protein (FABP) is one of the intracellular proteins, with a low molecular weight of approximately 15 kDa, that plays important roles in the transportation and metabolism of long-chain fatty acids. FABP... | |||
TMPY-01878 | L-FABP Protein, Human, Recombinant (His) | Human | E. coli |
Fatty acid-binding protein, liver, also known as Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, FABP1 and FABPL,is a cytoplasm protein which belongs to thecalycin superfamily and Fatty-acid bindi... | |||
TMPY-01482 | FABP4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
FABP4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is P04117. | |||
TMPH-03519 | ACP Protein, S. aureus, Recombinant (His) | Staphylococcus aureus | P. pastoris (Yeast) |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHi... | |||
TMPY-02174 | FABP5 Protein, Human, Recombinant | Human | E. coli |
Fatty acid-binding protein, also known as Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Psoriasis-associated fatty acid-binding protein homolog, E-FABP and FABP5, is a cytoplasm protein whic... | |||
TMPY-00605 | FABP3 Protein, Mouse, Recombinant | Mouse | E. coli |
FABP3 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.8 kDa and the accession number is P11404. | |||
TMPY-02239 | FABP3 Protein, Human, Recombinant | Human | E. coli |
FABP3 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.9 kDa and the accession number is P05413. | |||
TMPY-02103 | FABP4 Protein, Human, Recombinant (29 Ala/Thr, His) | Human | E. coli |
FABP4 Protein, Human, Recombinant (29 Ala/Thr, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16 kDa and the accession number is P15090. | |||
TMPH-03520 | ACP Protein, S. aureus, Recombinant (His & SUMO) | Staphylococcus aureus | E. coli |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli ex... | |||
TMPY-03276 | BLBP Protein, Human, Recombinant | Human | E. coli |
BLBP, also known as FABP7, is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic l... | |||
TMPH-00572 | ACP Protein, E. coli, Recombinant (His & SUMO) | E. coli | E. coli |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. | |||
TMPH-03518 | ACP Protein, S. aureus, Recombinant (GST) | Staphylococcus aureus | E. coli |
Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (GST) is expressed in E. coli expressio... | |||
TMPH-03431 | ACC1 Protein, S. cerevisiae, Recombinant (aa 217-775, His) | Saccharomyces cerevisiae | E. coli |
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nucle... | |||
TMPH-03432 | ACC1 Protein, S. cerevisiae, Recombinant (aa 2-581, His) | Saccharomyces cerevisiae | E. coli |
Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase. Involved in the synthesis of very-long-chain fatty acid synthesis which is required to maintain a functional nucle... | |||
TMPY-01118 | SLC27A4/FATP4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
SLC27A4/ATG4B complex might act as a new potential therapeutic target of lung tumor chemotherapy. The solute carrier 27A (SLC27A) gene family encodes fatty acid transport proteins (FATPs) and includes 6 members. Autism s... | |||
TMPH-03448 | EHT1 Protein, S. cerevisiae, Recombinant (His) | Saccharomyces cerevisiae | E. coli |
Displays enzymatic activity both for medium-chain fatty acid (MCFA) ethyl ester synthesis and hydrolysis (esterase activity). MCFA are toxic for yeast and this enzyme could thus be involved in their detoxification by est... | |||
TMPY-02249 | FABP6 Protein, Human, Recombinant | Human | E. coli |
Gastrotropin, also known as Fatty acid-binding protein 6, Ileal lipid-binding protein, ILBP, Intestinal 15 kDa protein, Intestinal bile acid-binding protein, I-BABP and FABP6, is a cytoplasm protein which belongs to t... | |||
TMPJ-00292 | CD36 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal ... | |||
TMPH-02825 | ACOX1 Protein, Mouse, Recombinant (Myc) | Mouse | E. coli |
Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. First enzyme of the fatty acid beta-oxidation pathway.; Shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing ch... | |||
TMPH-02764 | ACSL4 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
ACSL4 Protein, Mouse, Recombinant (His) is expressed in E. coli. | |||
TMPH-00160 | Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc) | Bacillus megaterium | E. coli |
Cytochrome P450 BM-3 Protein, Bacillus megaterium, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPH-00955 | ALOX12 Protein, Human, Recombinant (His) | Human | E. coli |
ALOX12 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPJ-00529 | FABP6 Protein, Human, Recombinant (His) | Human | E. coli |
Fatty Acid-Binding Protein 6 (FABP6) is cytoplasmic protein that binds long-chain fatty acids and other hydrophobic ligands which belongs to the calycin superfamily. FABP6 expression is restricted in the small intestine ... | |||
TMPY-02481 | ACOX1 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, ... | |||
TMPH-01634 | MLYCD Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Catalyzes the conversion of malonyl-CoA to acetyl-CoA. In the fatty acid biosynthesis MCD selectively removes malonyl-CoA and thus assures that methyl-malonyl-CoA is the only chain elongating substrate for fatty acid syn... | |||
TMPH-03524 | KAS III Protein, S. aureus, Recombinant (His & Myc) | Staphylococcus aureus | E. coli |
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may ther... | |||
TMPJ-00834 | ACADM Protein, Human, Recombinant (His) | Human | E. coli |
Medium-Chain Specific Acyl-CoA Dehydrogenase (ACADM) is a mitochondrial fatty acid beta-oxidation that belongs to the acyl-CoA dehydrogenase family. ACADM is a homotetramer enzyme that catalyzes the initial step of the m... | |||
TMPK-00764 | Apolipoprotein A-II/APOA2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
APOA2 is a protein implicated in triglyceride, fatty acid and glucose metabolism. In pigs, the APOA2 gene is located on pig chromosome 4 (SSC4) in a QTL region affecting fatty acid composition, fatness and growth traits.... | |||
TMPK-00795 | Apolipoprotein A-II/APOA2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
APOA2 is a protein implicated in triglyceride, fatty acid and glucose metabolism. In pigs, the APOA2 gene is located on pig chromosome 4 (SSC4) in a QTL region affecting fatty acid composition, fatness and growth traits.... | |||
TMPH-03755 | Ppard Protein, Human, Recombinant (His) | Human | E. coli |
Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosape... | |||
TMPH-02618 | CYP2E1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electr... | |||
TMPY-01140 | ACOT13/THEM2 Protein, Human, Recombinant (His) | Human | E. coli |
The metabolites of fatty acyl-Coenzyme A (CoA) and metabolic enzymes contribute to lipid biosynthesis, signal transduction, and gene transcription. Members of the acyl-CoA thioesterase (Acot) gene family hydrolyze fatty ... | |||
TMPH-01410 | GPR84 Protein, Human, Recombinant (hFc) | Human | P. pastoris (Yeast) |
Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and ... | |||
TMPH-03711 | PPAR gamma Protein, Xenopus laevis, Recombinant (His) | Xenopus laevis | E. coli |
Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the receptor binds to a promoter element in the gene for acyl-CoA oxidase and activates its transcript... | |||
TMPH-02716 | HADH Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10). Plays a role in the control of insulin secretion ... | |||
TMPH-01325 | FAAH2 Protein, Human, Recombinant (His) | Human | E. coli |
Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatt... | |||
TMPH-01612 | LSR Protein, Human, Recombinant (His) | Human | E. coli |
Probable role in the clearance of triglyceride-rich lipoprotein from blood. Binds chylomicrons, LDL and VLDL in presence of free fatty acids and allows their subsequent uptake in the cells. | |||
TMPH-03337 | MGLL Protein, Rat, Recombinant (His) | Rat | P. pastoris (Yeast) |
Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception o... | |||
TMPH-02822 | PNLIP Protein, Mouse, Recombinant (His & SUMO) | Mouse | E. coli |
Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activ... | |||
TMPH-00564 | FabG Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. | |||
TMPH-00433 | Ex-FABP Protein, Coturnix coturnix japonica, Recombinant (His & Myc) | Coturnix coturnix japonica | E. coli |
Siderocalin-like lipocalin tightly binding a variety of bacterial ferric siderophores, also binds long-chain unsaturated fatty acids such as linoleic acid, oleic acid, arachidonic acid and, with a lower affinity, long ch... | |||
TMPH-03291 | FABP3 Protein, Rat, Recombinant (His & Myc) | Rat | HEK293 Cells |
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. | |||
TMPH-01626 | LIPA Protein, Human, Recombinant (GST) | Human | E. coli |
Catalyzes the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. LIPA Protein, Human, Recombinant (GST) is expressed in ... | |||
TMPH-02245 | HADHB Protein, Human, Recombinant (GST) | Human | E. coli |
Mitochondrial trifunctional enzyme catalyzes the last three of the four reactions of the mitochondrial beta-oxidation pathway. The mitochondrial beta-oxidation pathway is the major energy-producing process in tissues and... | |||
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L7000 | Bioactive Lipid Compound Library | 385 compounds | |
A unique collection of 385 bioactive lipids related compounds for high throughput screening (HTS) and high content screening (HCS), including Agonists & Antagonists, Endocannabinoids, Farnesyl/geranylgeranyl derivates, ... | |||
L2510 | Lipid Metabolism Compound Library | 492 compounds | |
A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS). | |||
L1120 | AMPK-Targeted Compound Library | 80 compounds | |
80 well-chosen unique AMPK-targeted small molecules; | |||
L2540 | Gut Microbial Metabolite Library | 607 compounds | |
A unique collection of 607 gut microbial metabolites which can be used for HTS and HCS; |