Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.
説明 | ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS. |
ターゲット&IC50 | BRD4 BD2:3 nM (Kd), BRD4 BD2:4 nM (IC50), BRD3 BD2:13 nM (IC50), BRDT BD2:18 nM (IC50), BRD2 BD2:8 nM (IC50) |
別名 | ABBV744 |
分子量 | 491.55 |
分子式 | C28H30FN3O4 |
CAS No. | 2138861-99-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (91.54 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ABBV-744 2138861-99-9 Chromatin/Epigenetic Microbiology/Virology Proteases/Proteasome Epigenetic Reader Domain HIV Protease Inhibitor Antitumor Selective Oral inhibit Potent ABBV744 Drug-like Human immunodeficiency virus LNCaP CYP3A4 HIV ABBV 744 inhibitor