store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
10 mg | 在庫あり | ¥ 8,000 | |||
25 mg | 在庫あり | ¥ 13,000 | |||
50 mg | 在庫あり | ¥ 18,500 | |||
100 mg | 在庫あり | ¥ 26,000 | |||
200 mg | 在庫あり | ¥ 38,500 | |||
500 mg | 在庫あり | ¥ 65,000 |
説明 | Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities. |
ターゲット&IC50 | c-Kit:100 nM, PDGFRβ:39 nM, PDGFRα:51 nM, FGFR1:46 nM, VEGFR1:22 nM, VEGFR3:5.2 nM, VEGFR2:4 nM |
In vitro | Lenvatinib is a small-molecule tyrosine kinase inhibitor that inhibits vascular endothelial growth factor receptor (VEGFR1-3), fibroblast growth factor receptor (FGFR1-4), platelet-derived growth factor receptor α (PDGFRα), stem cell factor receptor (KIT), and rearranged during transfection (RET).?These receptors are important for tumor angiogenesis, and lenvatinib inhibits tumor angiogenesis by inhibiting function of these receptors[1]. |
別名 | E7080 (mesylate) |
分子量 | 522.96 |
分子式 | C22H23ClN4O7S |
CAS No. | 857890-39-2 |
store under nitrogen
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 8 mg/mL (15.2 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Lenvatinib mesylate 857890-39-2 Angiogenesis Apoptosis Tyrosine Kinase/Adaptors VEGFR FGFR PDGFR c-Kit c-RET Inhibitor E-7080 inhibit E7080 (mesylate) RET Vascular endothelial growth factor receptor Fibroblast growth factor receptor CD117 SCFR Lenvatinib Mesylate E7080 E 7080 Platelet-derived growth factor receptor Lenvatinib inhibitor