Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AS-0141 (Cdc7-IN-6) is a potent Cdc7 kinase inhibitor (IC50=4 nM) with anti-tumor activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 37,500 | |||
5 mg | 在庫あり | ¥ 95,500 | |||
10 mg | 在庫あり | ¥ 142,000 | |||
25 mg | 在庫あり | ¥ 226,000 | |||
50 mg | 在庫あり | ¥ 305,500 | |||
100 mg | 在庫あり | ¥ 411,000 |
説明 | AS-0141 (Cdc7-IN-6) is a potent Cdc7 kinase inhibitor (IC50=4 nM) with anti-tumor activity. |
In vitro | AS-0141 shows potent inhibitory activity (IC50<3 µΜ) in a range of solid tumor cell lines, including those of sarcoma (143B, CADO-ES1, RD-ES, A673), bladder (5673, RT1 12/84), colon and cecum (Colo-205, DLD-l, LS1034, SK-CO-l, SNU-C1), renal (U0.31), melanoma (A2058, A875), head-and-neck (CNE-2Z, RPMI-2650), and gastric (HGC-27) lineages[1]. |
別名 | Cdc7-IN-6, PNT-141, SRA-141 |
分子量 | 465.43 |
分子式 | C21H22F3N5O4 |
CAS No. | 1402057-88-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 76.5 mg/mL (164.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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AS-0141 1402057-88-8 Cell Cycle/Checkpoint CDK Cdc7-IN-6 SRA141 AS0141 PNT-141 AS 0141 SRA-141 PNT 141 SRA 141 PNT141 Inhibitor inhibitor inhibit