Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 15,500 | |||
5 mg | 在庫あり | ¥ 37,500 | |||
10 mg | 在庫あり | ¥ 60,500 | |||
25 mg | 在庫あり | ¥ 122,500 | |||
50 mg | 在庫あり | ¥ 178,000 | |||
100 mg | 在庫あり | ¥ 248,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 41,000 |
説明 | AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity. |
ターゲット&IC50 | TNF-α:8.4(human mononuclear cells), 8.1(whole blood), 9.0 (alveolar macrophages) |
In vitro | AZD7624 effectively suppresses LPS-induced TNFα production in human mononuclear cells, whole blood, and alveolar macrophages in vitro, exhibiting potent anti-inflammatory activity. This inhaled p38 inhibitor demonstrates significant efficacy with pIC50 values of 8.4, 8.1, and 9.0[1], respectively, highlighting its potential therapeutic application. |
別名 | AZD-7624 |
分子量 | 491.56 |
分子式 | C27H30FN5O3 |
CAS No. | 1095004-78-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (101.72 mM)
You can also refer to dose conversion for different animals. 詳細
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